Prof. Mohammed Khanfar

Professor of Drug Design and Medicinal Chemistry

Bio

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Prof. Khanfar's Biography

Dr. Khanfar received his undergraduate degree with first class honor in Pharmacy from University of Jordan. He pursued his graduate studies with a master degree in pharmaceutical sciences and then a Ph.D. in drug design from the University of Louisiana at Monroe, Monroe, USA. Dr. Khanfar completed a postdoctoral research fellowship at Center of Molecular Innovation and Drug Discovery (CMIDD), Northwestern University, IL where he conducted research in the laboratory of Prof. Richard B. Silverman (the inventor of the blockbuster drug LyricaTM). His research is currently funded by several national grants and he is a recipient of several national and international awards for his work on drug design and discovery.

Dr. Khanfar is a recipient of the prestigious Alexander von Humboldt (AvH) Foundation Fellowship for experienced researcher. Dr. Khanfar has published more than 50 articles in high impact peer-reviewed journals and one book chapter. He filed two patents in USA, and he is a member of several national and international organizations. Dr. Khanfar's research involves the use of state-of-the-art pharmaceutical, computational and medicinal chemistry technologies to design, synthesize and evaluate new molecules for the treatment of human disease and to probe biological systems with a particular emphasis on cancer and neurodegenerative diseases.

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Khanfar-CV.pdf (242.84 KB)

Publications

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Discovery of check point kinase 1 (Chk1) inhibitors as potential anticancer agents using ligand-based modelling and virtual screening

Journal Article ,
Discovery of check point kinase 1 (Chk1) inhibitors as potential anticancer agents using ligand-based modelling and virtual screening. (2015). Discovery of check point kinase 1 (Chk1) inhibitors as potential anticancer agents using ligand-based modelling and virtual screening. J Sil Vitro Pharmacol, 1, 1–11.

Oleuropein potently inhibits mammalian target of rapamycin: possible involvement of tandem anomeric hyperconjugation–Michael reaction

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Oleuropein potently inhibits mammalian target of rapamycin: possible involvement of tandem anomeric hyperconjugation–Michael reaction. (2015). Oleuropein potently inhibits mammalian target of rapamycin: possible involvement of tandem anomeric hyperconjugation–Michael reaction. Medicinal Chemistry Research, 24, 616–623.

Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

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Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. (2014). Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. Journal Of Molecular Modeling 20 (1), 1-15, 2014, 20, 2080.
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Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

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Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. (2014). Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. Journal Of Molecular Modeling, 20, 2080.

Development and characterization of 3-(benzylsulfonamido) benzamides as potent and selective SIRT2 inhibitors

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Development and characterization of 3-(benzylsulfonamido) benzamides as potent and selective SIRT2 inhibitors. (2014). Development and characterization of 3-(benzylsulfonamido) benzamides as potent and selective SIRT2 inhibitors. European Journal Of Medicinal Chemistry 76, 414-426, 2014, 76, 414–426.
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Development and characterization of 3-(benzylsulfonamido) benzamides as potent and selective SIRT2 inhibitors

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Development and characterization of 3-(benzylsulfonamido) benzamides as potent and selective SIRT2 inhibitors. (2014). Development and characterization of 3-(benzylsulfonamido) benzamides as potent and selective SIRT2 inhibitors. European Journal Of Medicinal Chemistry, 76, 414–426.

The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators

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The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators. (2014). The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators. Journal Of Computer-Aided Molecular Design 28 (5), 509-547, 2014, 28, 509–547.
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The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators

Journal Article ,
The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators. (2014). The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators. Journal Of Computer-Aided Molecular Design, 28, 509–547.

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

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Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. (2014). Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. European Journal Of Medicinal Chemistry 84, 454-465, 2014.
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Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3K$\gamma$) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

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Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3K$\gamma$) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. (2014). Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3K$\gamma$) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. European Journal Of Medicinal Chemistry, 84, 454–465.

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3K$\gamma$) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

Journal Article ,
Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3K$\gamma$) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. (2014). Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3K$\gamma$) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. European Journal Of Medicinal Chemistry, 84, 454–465.

Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron (III)-crosslinked beads as potential controlled release matrices

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Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron (III)-crosslinked beads as potential controlled release matrices. (2014). Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron (III)-crosslinked beads as potential controlled release matrices. Pharmaceutical Development And Technology 19 (7), 856-867, 2014, 19, 856–867.
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Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron (III)-crosslinked beads as potential controlled release matrices

Journal Article ,
Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron (III)-crosslinked beads as potential controlled release matrices. (2014). Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron (III)-crosslinked beads as potential controlled release matrices. Pharmaceutical Development And Technology, 19, 856–867.

Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker

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Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker. (2013). Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker. Journal Of Separation Science, 36, 3200–3205.

The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and pharmacophore modeling

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The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and pharmacophore modeling. (2013). The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and pharmacophore modeling. Medicinal Chemistry Research 22 (10), 4775-4786, 2013, 22, 4775–4786.
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The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and pharmacophore modeling

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The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and pharmacophore modeling. (2013). The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors: biological evaluation and pharmacophore modeling. Medicinal Chemistry Research, 22, 4775–4786.

Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone

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Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone. (2013). Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone. Journal Of Molecular Graphics And Modelling, 42, 39–49.

Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone

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Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone. (2013). Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone. Journal Of Molecular Graphics And Modelling, 42, 39–49.

Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol …

Journal Article ,
Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol …. (2013). Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol …. Journal Of Molecular Graphics And Modelling 42, 39-49, 2013.
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Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity relationship and pharmacophore modeling

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Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity relationship and pharmacophore modeling. (2013). Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity relationship and pharmacophore modeling. Bioorganic & Medicinal Chemistry, 21, 4678–4686.

Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity relationship and pharmacophore modeling

Journal Article ,
Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity relationship and pharmacophore modeling. (2013). Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity relationship and pharmacophore modeling. Bioorganic & Medicinal Chemistry, 21, 4678–4686.

Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity …

Journal Article ,
Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity …. (2013). Protective activity of (1S, 2E, 4R, 6R, 7E, 11E)-2, 7, 11-cembratriene-4, 6-diol analogues against diisopropylfluorophosphate neurotoxicity: Preliminary structure–activity …. Bioorganic & Medicinal Chemistry 21 (15), 4678-4686, 2013.
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Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors

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Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors. (2013). Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors. Journal Of Chemical Information And Modeling 53 (10), 2587-2612, 2013, 53, 2587–2612.
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Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors

Journal Article ,
Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors. (2013). Elaborate ligand-based modeling coupled with multiple linear regression and k nearest neighbor QSAR analyses unveiled new nanomolar mTOR inhibitors. Journal Of Chemical Information And Modeling, 53, 2587–2612.

Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker

Journal Article ,
Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker. (2013). Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker. Journal Of Separation Science 36 (19), 3200-3205, 2013, 36, 3200–3205.
Google scholar Link
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Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhi

Miscellaneous ,
Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhi. (2012). Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhi. American Association for Cancer Research.

Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c …

Journal Article ,
Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c …. (2012). Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c …. Cancer Research 72 (8_Supplement), 4778-4778, 2012.
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Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhi

Miscellaneous ,
Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhi. (2012). Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhi. American Association for Cancer Research.

Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids

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Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids. (2011). Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids. Planta Medica 77 (05), 467-476, 2011, 77, 467–476.
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Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids

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Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids. (2011). Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids. Planta Medica, 77, 467–476.

Latrunculin-Based Macrolides and Their Uses

Miscellaneous ,
Latrunculin-Based Macrolides and Their Uses. (2011). Latrunculin-Based Macrolides and Their Uses.

Methods for evaluation of structural and biological properties of antiinvasive natural products

Book Chapter ,
Methods for evaluation of structural and biological properties of antiinvasive natural products. (2011). Methods for evaluation of structural and biological properties of antiinvasive natural products. In Drug Design and Discovery (pp. 55–71). Humana Press.

Methods for evaluation of structural and biological properties of antiinvasive natural products

Journal Article ,
Methods for evaluation of structural and biological properties of antiinvasive natural products. (2011). Methods for evaluation of structural and biological properties of antiinvasive natural products. Drug Design And Discovery, 55-71, 2011.
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Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors

Journal Article ,
Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors. (2011). Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors. European Journal Of Medicinal Chemistry 46 (4), 1122-1130, 2011, 46, 1122–1130.
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Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors

Journal Article ,
Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors. (2011). Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors. European Journal Of Medicinal Chemistry, 46, 1122–1130.

Latrunculin-Based Macrolides and Their Uses

Journal Article ,
Latrunculin-Based Macrolides and Their Uses. (2011). Latrunculin-Based Macrolides and Their Uses. Us Patent App. 12/960,681, 2011.
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Discovery of novel GSK-3$\beta$ inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening

Journal Article ,
Discovery of novel GSK-3$\beta$ inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening. (2010). Discovery of novel GSK-3$\beta$ inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening. Journal Of Medicinal Chemistry, 53, 8534–8545.

3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches

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3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches. (2010). 3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches. European Journal Of Medicinal Chemistry 45 (9), 3662-3668, 2010, 45, 3662–3668.
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Pachycladins A−E, Prostate Cancer Invasion and Migration Inhibitory Eunicellin-Based Diterpenoids from the Red Sea Soft Coral Cladiella pachyclados

Journal Article ,
Pachycladins A−E, Prostate Cancer Invasion and Migration Inhibitory Eunicellin-Based Diterpenoids from the Red Sea Soft Coral Cladiella pachyclados. (2010). Pachycladins A−E, Prostate Cancer Invasion and Migration Inhibitory Eunicellin-Based Diterpenoids from the Red Sea Soft Coral Cladiella pachyclados. Journal Of Natural Products 73 (5), 848-853, 2010.
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Discovery of novel GSK-3$\beta$ inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening

Journal Article ,
Discovery of novel GSK-3$\beta$ inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening. (2010). Discovery of novel GSK-3$\beta$ inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening. Journal Of Medicinal Chemistry, 53, 8534–8545.

3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches

Journal Article ,
3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches. (2010). 3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches. European Journal Of Medicinal Chemistry, 45, 3662–3668.

Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening

Journal Article ,
Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening. (2010). Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand-and structure-based virtual screening. Journal Of Medicinal Chemistry 53 (24), 8534-8545, 2010.
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Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the University of Louisiana at Monroe in Partial Fulfillment of the Requirements for th

Thesis ,
Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the University of Louisiana at Monroe in Partial Fulfillment of the Requirements for th. (2010). Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the University of Louisiana at Monroe in Partial Fulfillment of the Requirements for th. University of Louisiana at Monroe.

Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the …

Journal Article ,
Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the …. (2010). Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the …. University Of Louisiana At Monroe, 2010.
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Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the University of Louisiana at Monroe in Partial Fulfillment of the Requirements for th

Thesis ,
Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the University of Louisiana at Monroe in Partial Fulfillment of the Requirements for th. (2010). Computer-assisted Design and Discovery of Actin Polymerization and GSK-3 [beta] Inhibitors Based on Marine Natural Products: A Dissertation Submitted to the Faculty of the University of Louisiana at Monroe in Partial Fulfillment of the Requirements for th. University of Louisiana at Monroe.

Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors

Journal Article ,
Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors. (2010). Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors. Bioorganic & Medicinal Chemistry 18 (2), 496-507, 2010.
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Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure–activity relationship and molecular modeling studies

Journal Article ,
Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure–activity relationship and molecular modeling studies. (2010). Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure–activity relationship and molecular modeling studies. Chemmedchem: Chemistry Enabling Drug Discovery 5 (2), 274-285, 2010.
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Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

Journal Article ,
Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. (2010). Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. Biochemical Pharmacology 80 (10), 1497-1506, 2010, 80, 1497–1506.
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Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

Journal Article ,
Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. (2010). Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. Biochemical Pharmacology, 80, 1497–1506.

Pachycladins A- E, prostate cancer invasion and migration inhibitory eunicellin-based diterpenoids from the Red Sea soft coral Cladiella pachyclados

Journal Article ,
Pachycladins A- E, prostate cancer invasion and migration inhibitory eunicellin-based diterpenoids from the Red Sea soft coral Cladiella pachyclados. (2010). Pachycladins A- E, prostate cancer invasion and migration inhibitory eunicellin-based diterpenoids from the Red Sea soft coral Cladiella pachyclados. Journal Of Natural Products, 73, 848–853.

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