Dr. Ibrahim Salman

Associate Professor of Pharmacology and Physiology, Head of Department of Pharmacy Practice

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Dr Ibrahim Salman, PhD

Dr. Salman is an Associate Professor of Pharmacology and Physiology and an Award-Winning Neuroscientist. He received his undergraduate degree in pharmacy from the University of Baghdad in 2003 and earned his doctorate from the Australian School of Advanced Medicine at Macquarie University (Sydney) in 2015. In 2016, Dr. Salman also obtained a graduate certificate in Applied Pharmacy Practice from the Australian Pharmaceutical Society (APS). He is a certified pharmacist with the Australian Health Practitioner Regulation Agency (AHPRA) and an active member of the APS.

Previously, Dr. Salman was affiliated with the Division of Pulmonology, Allergy, and Immunology in the Department of Pediatrics at the School of Medicine, Case Western Reserve University (CWRU), Cleveland, Ohio, United States. There, he completed his postdoctoral training and subsequently held the position of Senior Research Associate in the same department.

Dr. Salman’s research primarily focuses on the autonomic neuroregulation of cardiovascular and renal functions. He employs experimental rodent models in both normal and disease states to elucidate mechanisms related to altered cardiovascular autonomic control in conditions such as hypertension, metabolic syndrome, and chronic kidney disease. His research approach is multidisciplinary, spanning whole-animal physiology and pharmacology to electrophysiology, including techniques like whole-fiber neural recordings and neurostimulation. He maintains key international collaborations with experts in the US, Australia, and New Zealand. Dr. Salman is one of the few researchers worldwide capable of chronically recording sympathetic nerve activity in rats, and has received numerous research awards, including most recently the 2024 Science PINS Prize for Neuromodulation.

With many years of cumulative research experience, Dr. Salman has contributed to various research papers and abstracts in the field of autonomic neuroscience. He serves as a reviewer for leading medical journals in his field, including the American Journal of Physiology, Frontiers in Physiology, Basic and Clinical Autonomic Neuroscience, Scientific Reports, Acta Physiologica, Experimental and Clinical Hypertension, and Circulation. 

Dr. Salman is also a member of the American Heart Association (USA), the American Physiological Society (USA), the International Society of Hypertension (UK), and the American Society for Pharmacology and Experimental Therapeutics (USA).

Biography

Publications

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Low intensity stimulation of aortic baroreceptor afferent fibers as a potential therapeutic alternative for hypertension treatment

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Low intensity stimulation of aortic baroreceptor afferent fibers as a potential therapeutic alternative for hypertension treatment. (2022). Scientific Reports 12 (1), 1-12, 2022.

Synthesis and Biological Evaluation of Thiazole-Based Fibroblast Growth Factor Receptor-1 Inhibitors.

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Synthesis and Biological Evaluation of Thiazole-Based Fibroblast Growth Factor Receptor-1 Inhibitors. (2022). Anti-Cancer Agents in Medicinal Chemistry, 2022.

Neuromodulation Device

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Neuromodulation Device. (2022). US Patent App. 17 619,567, 2022.

Regional functional and structural abnormalities within the aorta as a potential driver of vascular disease in metabolic syndrome

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Regional functional and structural abnormalities within the aorta as a potential driver of vascular disease in metabolic syndrome. (2021). Experimental Physiology 106 (3), 771-788, 2021, 106, 771-788.

Assessment of the physiological and pathological structural differences along the aorta in a rat model of metabolic syndrome

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Assessment of the physiological and pathological structural differences along the aorta in a rat model of metabolic syndrome. (2021). Circulation 144 (Suppl_1), A13462-A13462, 2021.

Neuromodulation Of The Renal Nerves In Spontaneously Hypertensive Rats

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Neuromodulation Of The Renal Nerves In Spontaneously Hypertensive Rats. (2021). Circulation 144 (Suppl_1), A12867-A12867, 2021.

DIFFERENTIAL EXPRESSION OF VASCULAR DYSFUNCTION OF SMALLER DIAMETER ARTERIES IN A RODENT MODEL OF METABOLIC SYNDROME

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DIFFERENTIAL EXPRESSION OF VASCULAR DYSFUNCTION OF SMALLER DIAMETER ARTERIES IN A RODENT MODEL OF METABOLIC SYNDROME. (2021). Journal of Hypertension 39, e250, 2021.

CENTRAL INTEGRATION OF LEFT VERSUS RIGHT BARORECEPTOR AFFERENT INPUT IN FEMALE SPONTANEOUSLY HYPERTENSIVE RATS

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CENTRAL INTEGRATION OF LEFT VERSUS RIGHT BARORECEPTOR AFFERENT INPUT IN FEMALE SPONTANEOUSLY HYPERTENSIVE RATS. (2021). Journal of Hypertension 39, e250-e251, 2021.

REGIONAL AORTIC VASCULAR DYSFUNCTION IN A RODENT MODEL OF METABOLIC SYNDROME

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REGIONAL AORTIC VASCULAR DYSFUNCTION IN A RODENT MODEL OF METABOLIC SYNDROME. (2021). Journal of Hypertension 39, e255, 2021.

Laterality Influences Central Integration of Baroreceptor Afferent Input in Male and Female Sprague Dawley Rats

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Laterality Influences Central Integration of Baroreceptor Afferent Input in Male and Female Sprague Dawley Rats. (2020). Laterality Influences Central Integration of Baroreceptor Afferent Input in Male and Female Sprague Dawley Rats, 11. (Original work published 2020)

Neuromodulation of baroreceptor reflex

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Neuromodulation of baroreceptor reflex. (2020). US Patent App. 16 643,877, 2020.

Laterality Influences Central Integration of Baroreceptor Afferent Input in Male and Female Sprague Dawley Rats

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Laterality Influences Central Integration of Baroreceptor Afferent Input in Male and Female Sprague Dawley Rats. (2020). Frontiers in Physiology 11, 499, 2020, 11.

A18700 Differential central modulation of right versus left baroreceptor afferent input in hypertension

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A18700 Differential central modulation of right versus left baroreceptor afferent input in hypertension. (2018). Journal of Hypertension 36, e93, 2018.

Abstract P110: low Intensity stimulation of Aortic Baroreceptors as a potential therapeutic alternative for hypertension treatment

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Abstract P110: low Intensity stimulation of Aortic Baroreceptors as a potential therapeutic alternative for hypertension treatment. (2017). Hypertension 70 (suppl_1), AP110-AP110, 2017.

Chronic kidney disease impairs renal nerve and haemodynamic reflex responses to vagal afferent input through a central mechanism

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Chronic kidney disease impairs renal nerve and haemodynamic reflex responses to vagal afferent input through a central mechanism. (2017). Autonomic Neuroscience 204, 65-73, 2017, 204, 65-73. (Original work published 2017)

Major autonomic neuroregulatory pathways underlying short-and long-term control of cardiovascular function

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Major autonomic neuroregulatory pathways underlying short-and long-term control of cardiovascular function. (2016). Current Hypertension Reports 18 (3), 1-18, 2016, 18(3), 18. (Original work published 2016)

Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease

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Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease. (2015). Autonomic Neuroscience: Basic and Clinical 192, 40, 2015, 63(4), 804-810. (Original work published 2014)

Direct conscious telemetry recordings demonstrate increased renal sympathetic nerve activity in rats with chronic kidney disease

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Direct conscious telemetry recordings demonstrate increased renal sympathetic nerve activity in rats with chronic kidney disease. (2015). Frontiers in Physiology 6, 218, 2015, 6, 218. (Original work published 2015)

Abnormal central control underlies impaired baroreflex control of heart rate and sympathetic nerve activity in female Lewis polycystic kidney rats

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Abnormal central control underlies impaired baroreflex control of heart rate and sympathetic nerve activity in female Lewis polycystic kidney rats. (2015). Journal of Hypertension 33 (7), 1418-1428, 2015, 33(7), 1418-1428.

Current approaches to quantifying tonic and reflex autonomic outflows controlling cardiovascular function in humans and experimental animals

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Current approaches to quantifying tonic and reflex autonomic outflows controlling cardiovascular function in humans and experimental animals. (2015). Current Hypertension Reports 17 (11), 1-18, 2015, 17(11), 84. (Original work published 2015)

Cardiovascular autonomic dysfunction in chronic kidney disease: a comprehensive review

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Cardiovascular autonomic dysfunction in chronic kidney disease: a comprehensive review. (2015). Current Hypertension Reports 17 (8), 1-20, 2015, 17(8), 59. (Original work published 2015)

Loranthus ferrugineus: A mistletoe from traditional uses to laboratory bench

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Loranthus ferrugineus: A mistletoe from traditional uses to laboratory bench. (2015). Korean Pharmacopuncture Institute, 2015.

Abnormal central control underlies impaired baroreflex control of heart rate and sympathetic nerve activity in female Lewis polycystic kidney rats

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Abnormal central control underlies impaired baroreflex control of heart rate and sympathetic nerve activity in female Lewis polycystic kidney rats. (2015). Abnormal, 33(7), 1418-1428. (Original work published 2015)

Opposing changes in thoracic and abdominal aortic biomechanical properties in rodent models of vascular calcification and hypertension

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Opposing changes in thoracic and abdominal aortic biomechanical properties in rodent models of vascular calcification and hypertension. (2014). Opposing Changes in Thoracic and Abdominal Aortic Biomechanical Properties in Rodent Models of Vascular Calcification and Hypertension, 307(2), H143 - H151. (Original work published 2014)

Opposing changes in thoracic and abdominal aortic biomechanical properties in rodent models of vascular calcification and hypertension

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Opposing changes in thoracic and abdominal aortic biomechanical properties in rodent models of vascular calcification and hypertension. (2014). American Journal of Physiology-Heart and Circulatory Physiology 307 (2 …, 2014, 307, H143–H151.

Cardiovascular autonomic dysfunction in chronic kidney disease

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Cardiovascular autonomic dysfunction in chronic kidney disease. (2014). Macquarie University, Faculty of Medicine and Health Sciences, Australian …, 2014.

Articles in PresS. Am J Physiol Heart Circ Physiol (May 16, 2014). doi: 10.1152/ajpheart. 00139.2014

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Articles in PresS. Am J Physiol Heart Circ Physiol (May 16, 2014). doi: 10.1152/ajpheart. 00139.2014. (2014).

Chronic Effects of Andrographis paniculata Chloroform Extract in Spontaneously Hypertensive Rats

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Chronic Effects of Andrographis paniculata Chloroform Extract in Spontaneously Hypertensive Rats. (2012). Journal of Pharmaceutical Sciences and Research 4 (9), 1924, 2012.

Study of surface activity of piroxicam at the interface of palm oil esters and various aqueous phases

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Study of surface activity of piroxicam at the interface of palm oil esters and various aqueous phases. (2012). Pakistan Journal of Pharmaceutical Sciences 25 (2), 429-433, 2012.

291 IMPAIRED RENAL SYMPATHOINHIBITORY RESPONSES TO VAGAL AFFERENT STIMULATION IN CHRONIC KIDNEY DISEASE

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291 IMPAIRED RENAL SYMPATHOINHIBITORY RESPONSES TO VAGAL AFFERENT STIMULATION IN CHRONIC KIDNEY DISEASE. (2012). Journal of Hypertension 30, e86-e87, 2012.

Baroreflex control of the renal sympathetic nerve in autosomal recessive cystic kidney disease

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Baroreflex control of the renal sympathetic nerve in autosomal recessive cystic kidney disease. (2012). Hypertension 60 (2), 494-494, 2012.

Preparation and in vitro evaluation of mebeverine HCl colon-targeted drug delivery system

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Preparation and in vitro evaluation of mebeverine HCl colon-targeted drug delivery system. (2011). Pharmaceutical Development and Technology 16 (4), 331-342, 2011.

Development of a stepping force analgesic meter for a rat arthritic model

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Development of a stepping force analgesic meter for a rat arthritic model. (2011). Sensors 11, 5058-5070, 2011.

Stability studies of nano-scaled emulsions containing ibuprofen for topical delivery

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Stability studies of nano-scaled emulsions containing ibuprofen for topical delivery. (2011). International Journal of Drug Delivery 3 (1), 2011.

Study of pseudoternary phase diagram behaviour and the effect of several tweens and spans on palm oil esters characteristics

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Study of pseudoternary phase diagram behaviour and the effect of several tweens and spans on palm oil esters characteristics. (2011). International Journal of Drug Delivery 3 (1), 2011.

Characterization of renal hemodynamic and structural alterations in rat models of renal impairment: role of renal sympathoexcitation.

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Characterization of renal hemodynamic and structural alterations in rat models of renal impairment: role of renal sympathoexcitation. (2011). Journal of Nephrology 24 (1), 68-77, 2011.

Influence of high dietary sodium intake on functional contribution of renal α1a-adrenoceptor of SHR

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Influence of high dietary sodium intake on functional contribution of renal α1a-adrenoceptor of SHR. (2011). Advances in Clinical and Experimental Medicine 20 (1), 47-55, 2011.

In vitro permeation and in vivo anti-inflammatory and analgesic properties of nanoscaled emulsions containing ibuprofen for topical delivery

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In vitro permeation and in vivo anti-inflammatory and analgesic properties of nanoscaled emulsions containing ibuprofen for topical delivery. (2011). International Journal of Nanomedicine 6, 387, 2011.

Modification and validation of an HPLC method for quantification of piroxicam

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Modification and validation of an HPLC method for quantification of piroxicam. (2011). International Journal of Drug Delivery 3 (1), 2011.

Renal sympathetic nervous system hyperactivity in early streptozotocin‐induced diabetic kidney disease

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Renal sympathetic nervous system hyperactivity in early streptozotocin‐induced diabetic kidney disease. (2011). Neurourology and Urodynamics 30 (3), 438-446, 2011.

A Special Focus on the Role of α1D-Adrenoreceptors in the Assessment of Renal Tubular Sodium Re-absorptive Responses in Spontaneously Hypertensive Rats Subjected to High Sodium …

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A Special Focus on the Role of α1D-Adrenoreceptors in the Assessment of Renal Tubular Sodium Re-absorptive Responses in Spontaneously Hypertensive Rats Subjected to High Sodium …. (2011). YAKUGAKU ZASSHI 131 (3), 431-436, 2011.

Stability studies of nano-cream containing piroxicam

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Stability studies of nano-cream containing piroxicam. (2010). International Journal of Drug Delivery 2 (4), 2010.

High fructose feeding causes stiffer arteries in sprague-dawley rats

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High fructose feeding causes stiffer arteries in sprague-dawley rats. (2010). Journal of Investigative Medicine 58 (2), 446, 2010.

Formulation and characterization of palm oil esters based nano-cream for topical delivery of piroxicam

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Formulation and characterization of palm oil esters based nano-cream for topical delivery of piroxicam. (2010). International Journal of Drug Delivery 2 (4), 2010.

Role of renal sympathetic nervous system in the control of renal potassium handling.

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Role of renal sympathetic nervous system in the control of renal potassium handling. (2010). Journal of Nephrology 23 (3), 291-296, 2010.

HPLC and Anti-Inflammatory Studies of the Flavonoid Rich Chloroform Extract Fractionof Orthosiphon Stamineus Leaves

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HPLC and Anti-Inflammatory Studies of the Flavonoid Rich Chloroform Extract Fractionof Orthosiphon Stamineus Leaves. (2010). Molecules 15 (6), 4452-4466, 2010.

Vasorelaxant effect of diterpenoid lactones from Andrographis paniculata chloroform extract on rat aortic rings

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Vasorelaxant effect of diterpenoid lactones from Andrographis paniculata chloroform extract on rat aortic rings. (2010). Pharmacognosy Research 2 (4), 242, 2010.

Pharmacological mechanisms underlying the vascular activities of Loranthus ferrugineus Roxb. in rat thoracic aorta

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Pharmacological mechanisms underlying the vascular activities of Loranthus ferrugineus Roxb. in rat thoracic aorta. (2010). Journal of Ethnopharmacology 127 (1), 19-25, 2010, 127, 19–25.

Antioxidant and hepatoprotective effects of Murdannia bracteata methanol extract

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Antioxidant and hepatoprotective effects of Murdannia bracteata methanol extract. (2010). Journal of Acupuncture and Meridian Studies 3 (3), 197-202, 2010.

Cardiovascular activity of the n-butanol fraction of the methanol extract of Loranthus ferrugineus Roxb.

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Cardiovascular activity of the n-butanol fraction of the methanol extract of Loranthus ferrugineus Roxb. (2010). Brazilian Journal of Medical and Biological Research 43, 186-194, 2010, 43, 186–194.

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