Dr. Khaled Abdelmonem Elnahriry

Senior Lecturer of Medicinal Chemistry

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Dr. Khaled Elnahriry

Dr. Khaled A. Elnahriry is a medicinal chemist with a distinguished academic and research career, currently serving as a Senior Lecturer in the Department of Pharmaceutical Sciences at Alfaisal University, Riyadh, Saudi Arabia. He holds a PhD in Medicinal Chemistry from the Monash Institute of Pharmaceutical Sciences (MIPS), Monash University, Australia, completed in October 2023. His doctoral research focused on the structural and functional characterisation of novel peptide toxins derived from Australian sea anemones, utilising advanced methodologies such as nuclear magnetic resonance (NMR) spectroscopy, peptide synthesis, and recombinant protein expression. This research led to the discovery of peptides with potential therapeutic applications, including cytotoxic, KV channel-blocking, and TRPV1-blocking (analgesic) activities, contributing significantly to drug discovery.

Dr. Elnahriry’s academic journey also includes a Master of Science in Pharmaceutical Sciences, specialising in Phytochemistry and Analytical Chemistry, from Suez Canal University, Egypt, where he developed validated RP-HPLC and HPTLC methods for the quality control and stability studies of phytopharmaceuticals. His foundational education began with a Bachelor of Science in Pharmaceutical Sciences from the same institution.

In addition to his academic accomplishments, Dr. Elnahriry has extensive teaching experience. He has taught undergraduate pharmaceutical sciences courses in diverse international settings, including Australia and Egypt, covering subjects such as medicinal chemistry, pharmacognosy, phytochemistry, and analytical methods.

Dr. Elnahriry’s research expertise spans chemical synthesis, chromatographic and spectrometric techniques, molecular biology, and protein structure determination. He has published extensively in high-impact journals, with notable contributions to the understanding of bioactive peptides from marine organisms. His work has been showcased at various scientific conferences worldwide, earning him recognition and multiple awards, including scholarships from Monash University and international publication awards from Suez Canal University.

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Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni.

Journal Article ,
KA, et al. E. (2023). Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni. BBA-Proteins Proteom, 1872(1).

Genomic, functional, and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family

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LM*, E. K. A. (2023). Genomic, functional, and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family. BMC Biol, 21(1).

Alkyne-Bridged α-Conotoxin Vc1.1 potently reverses mechanical allodynia in neuropathic pain models

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Alkyne-Bridged α-Conotoxin Vc1.1 potently reverses mechanical allodynia in neuropathic pain models. (2021). J Med Chem. , 64(6), 12.

Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa

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Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa. (2019). TOXICON, 168(1).

Validated HPLC method for simultaneous estimation of khellol glucoside, khellin and visnagin in Ammi visnaga L. fruits and pharmaceutical preparations.

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Validated HPLC method for simultaneous estimation of khellol glucoside, khellin and visnagin in Ammi visnaga L. fruits and pharmaceutical preparations. (2015). Nat Prod Res., 29(7).

Validated HPLC and HPTLC Methods for Simultaneous Determination of Colchicine and Khellin in Pharmaceutical Formulations.

Journal Article ,
Validated HPLC and HPTLC Methods for Simultaneous Determination of Colchicine and Khellin in Pharmaceutical Formulations. (2013). J Chromatogr Sci., 51(3).

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