Dr. Santosh Kumar

Lecturer of Pharmacology

Bio

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Education:                          
•  MBBS 2004 Aga Khan University, Karachi, Pakistan
 
Certification / License for medical practice:
•  MERC                                              2012                  Association of American Medical Colleges, USA
•  MD (ECFMG Certification)            2008                  USA
•  Registration with PMDC               2006-2015        Pakistan Medical and Dental Council, Pakistan

Professional Training/ Positions:
•  Lecturer – College of Medicine                 2011-Present     Alfaisal University, Riyadh, KSA
•  Post-Doc                                                    2009-2010          University of Cincinnati, Ohio, USA
•  Clinical Observer & Research Associate  2009-2010         The Jewish Hospital of Cincinnati, Ohio, USA
•  Research Medical Officer                          2006-2008          Aga Khan University, Karachi, Pakistan.
•  Intern                                                          2004-2005          Aga Khan University Hospital, Pakistan.

Research Interests:
•  Cardiovascular Biology:
o Molecular biology of adipose tissue dysregulation in obesity leading to metabolic derangements, including increased cardiovascular risk and insulin resistance.
o Role of homocysteine in cardiovascular and other metabolic disorders.
o Non-invasive determination of electrophysiological functions of the heart
o Non-invasive automated measurement of blood pressure
•  Broad aspects of human development, including early child development.
•  Medical Education

Publications Peer Reviewed Journal Articles/Abstracts:

Arain SA, Kumar S, Yaqinuddin A, Meo SA. Vertical integration of head, neck, and special senses module in undergraduate medical curriculum. Adv Physiol Educ. 2020 Sep 1; 44(3): 344-349. DOI: 10.1152/advan.00173.2019. PMID: 32568004.

Alam SF, Kumar S, Ganguly P. Measurement of homocysteine: a historical perspective. J Clin Biochem Nutr. 2019 Nov; 65(3): 171-177. DOI: 10.3164/jcbn.19-49. PMID: 31777417.

Chatterjee TK, Idelman G, Blanco V, Blomkalns AL, Piegore MG Jr, Weintraub DS, Kumar S, Rajsheker S, Manka D, Rudich SM, Tang Y, Hui DY, Bassel-Duby R, Olson EN, Lingrel JB, Ho SM, Weintraub NL. Histone deacetylase 9 is a negative regulator of adipogenic differentiation. J Biol Chem. 2011 Aug 5;286(31):27836-47. Epub 2011 Jun 16.

Chatterjee TK, Idelman G, Blomkalns AL, Blanco V, Weintraub DS, Piegore MG, Rajsheker S, Kumar S, Manka D, Tang Y, Neltner BS, Rudich SM, Hui DY, Bassel-Duby R, Olson EN, Weintraub NL. Histone Deacetylase 9 (HDAC9) is an Endogenous Inhibitor of Adipocyte Differentiation: Role in Diet-Induced Obesity. Circulation. 2010 Nov; 122(21 Supplement): A15527.

Naqvi KR, Parigi L, Vellani CW, Kumar S. Noninvasive method for determining blood pressure and contours of arterial and volume pulses. Journal of Biomedical Science and Engineering (JBiSE). 2008 Aug; 1(2): 79-84.

Arif H, Aijaz B, Islam M, Aftab U, Kumar S, Shafqat S. Drug compliance after stroke and myocardial infarction: A comparative study. Neurology India. 2007 Jun; 55(2): 130-135.

Saeed SA, Rasheed H, Kumar S, Ali TM, Butt MU, Dhangana R, Jafri A, Zehra S, Gilani AH. Involvement of cyclooxygenase, phospholipase C and MAP kinase pathways in human platelet aggregation mediated by the synergistic interaction of platelet activating factor and arachidonic acid. Pakistan Journal of Biological Sciences. 2003 May; 6(10): 918-924.

Saeed SA, Rasheed H, Kumar S, Ali TM, Butt MU, Saud MF, Dhangana R, Jafri A, Zehra S, Gilani AH. New aspects of cyclooxygenase and signaling inhibitors in arachidonic acid (AA) and platelet activating factor (PAF) mediated platelet aggregation. Biochemical Society Transactions. 2002 Nov; 30(6): A130-Abstract.

Poster Presentation

Kumar S, Senok A, Rohra DK, Alshedoukhy A. (2013, January). Refinement of PBL evaluation criteria by tutors results in enhanced active engagement of students and objective evaluation  process. Poster presented at: 10th Asia Pacific Medical Education Conference, Singapore.
Vellani C, Kumar S, Yusuf M, Mahmud S. (2008, December). Exercise induced changes in ventricular depolarization vectors. Poster presented at: Health Sciences Research Assembly, Aga Khan University; Karachi, Pakistan.
Vellani C, Kumar S, Naqvi K. (2007, May). Comparison of systolic and diastolic pressures identified by Korotkoff sounds and pressure pulses. Poster presented at: Sixth Annual Research Retreat, Department of Medicine, Aga Khan University; Karachi, Pakistan.
Vellani C, Kumar S, Naqvi K. (2007, April). Identification of systolic and diastolic points in sphygmomanometer cuff pressures by Korotkoff sounds and pressure pulses. Poster presented at: Health Sciences Research Assembly, Aga Khan University; Karachi, Pakistan.
Vellani C, Yusuf M, Mahmud S, Ajaz-ul-Haq, Kumar S. (2006, May). Depolarization Vectors in Reversible Myocardial Ischemia. Poster presented at: Fifth Annual Research Retreat, Department of Medicine, Aga Khan University; Karachi, Pakistan.
Arif H, Islam M, Aijaz B, Aftab U, Kumar S, Shafqat S. (2005, March). Drug compliance in stroke and myocardial infarction patients: a comparative study. Poster presented at: Health Sciences Research Assembly, Aga Khan University; Karachi, Pakistan.
Saeed S, Rasheed H, Kumar S, Ali T, Butt M, Saud M, Dhangana R, Jafri A, Zehra S, Gilani A. (2002, July). New aspects of cyclooxygenase and signaling inhibitors in arachidonic acid (AA) and platelet activating factor (PAF) mediated platelet aggregation. Poster presented at: The Biochemical Society, 677th Meeting, Cardiff University, Wales; Cardiff, Wales, United Kingdom.

Oral Presentation

Vellani C, Yusuf M, Kumar S, Mahmud S. (2009, May). Exercise induced changes in ventricular depolarization vectors. Oral Presentation presented at: Department of Medicine Research Day 2009, Aga Khan University; Karachi, Pakistan.
Vellani C, Yusuf M, Mahmud S, Ajaz-ul-Haq, Kumar S. (2006, February). Depolarization vectors in reversible myocardial ischemia. Oral Presentation presented at: 3rd International Conference on Cardiac Electrophysiology, Armed Forces Institute of Cardiology and National Institute of Heart Diseases; Rawalpindi, Pakistan.

 

Publications

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Histone deacetylase 9 is a negative regulator of adipogenic differentiation

Journal Article Wed, 12/31/2014 - 00:18,
Histone deacetylase 9 is a negative regulator of adipogenic differentiation. (2011). Histone deacetylase 9 is a negative regulator of adipogenic differentiation. Journal Of Biological Chemistry, 286, 27836–27847.

Noninvasive method for determining blood pressure and contours of arterial and volume pulses

Journal Article Wed, 12/31/2014 - 00:18,
Noninvasive method for determining blood pressure and contours of arterial and volume pulses. (2008). Noninvasive method for determining blood pressure and contours of arterial and volume pulses. Journal Of Biomedical Science And Engineering, 1, 79-84.

Drug compliance after stroke and myocardial infarction: A comparative study.

Journal Article Wed, 12/31/2014 - 00:18,
Drug compliance after stroke and myocardial infarction: A comparative study. (2007). Drug compliance after stroke and myocardial infarction: A comparative study. Neurology India, 55.

Involvement of Cyclooxygenase, Phospholipase C and Map Kinase Pathways in Human Platelet Aggregation Mediated by the Synergistic Interaction of Platelet Activating Factor and Arachidonic Acid

Journal Article Wed, 12/31/2014 - 00:18,
Involvement of Cyclooxygenase, Phospholipase C and Map Kinase Pathways in Human Platelet Aggregation Mediated by the Synergistic Interaction of Platelet Activating Factor and Arachidonic Acid. (2003). Involvement of Cyclooxygenase, Phospholipase C and Map Kinase Pathways in Human Platelet Aggregation Mediated by the Synergistic Interaction of Platelet Activating Factor and Arachidonic Acid. Pakistan Journal Of Biological Sciences, 6, 918–924.

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Classes

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PBL Year-2 Semester-3

Twice weekly problem-based learning (PBL) sessions for both male and female batches, for academic year 2012-13.

Professional Skills (PRO-365)

During Spring semester only for CNS-361 and SSS-362 blocks.

PBL Year-2 Semester-4

Twice weekly problem-based learning sessions for both male and female batches, for academic year 2012-13.

PBL Year-2 Semester-3

Twice weekly problem-based learning (PBL) sessions, for academic year 2013-14.

PBL Year-3 Semester-5

Twice weekly problem-based learning (PBL) sessions for both male and female batches - Standby, for academic year 2013-14.

PBL Year-3 Semester-6

Twice weekly problem-based learning sessions for both male and female batches, for academic year 2013-14.

PBL Year-3 Semester-5

Twice weekly problem-based learning sessions for both male and female batches, for academic year 2014-15.