Dr. Mattheus F.A. Goosen

Associate Vice President for Research & Graduate Studies

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Biodata Mattheus Goosen

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Large-scale insect cell culture

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Large-scale insect cell culture. (1992). Large-scale insect cell culture. Current Opinion In Biotechnology 3 (2), 99-104, 1992.
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Recombinant protein production in insect cell cultures infected with a temperature-sensitive baculovirus

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Recombinant protein production in insect cell cultures infected with a temperature-sensitive baculovirus. (1992). Recombinant protein production in insect cell cultures infected with a temperature-sensitive baculovirus. Cytotechnology 9 (1), 141-147, 1992.
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Recombinant β‐galactosidase production in serum‐free medium by insect cells in a 14‐L airlift bioreactor

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Recombinant β‐galactosidase production in serum‐free medium by insect cells in a 14‐L airlift bioreactor. (1992). Recombinant β‐galactosidase production in serum‐free medium by insect cells in a 14‐L airlift bioreactor. Biotechnology Progress 8 (6), 567-571, 1992.
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Assessment of virus production and chloramphenicol acetyl transferase expression by insect cells in serum‐free and serum‐supplemented media using a temperature‐sensitive …

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Assessment of virus production and chloramphenicol acetyl transferase expression by insect cells in serum‐free and serum‐supplemented media using a temperature‐sensitive …. (1991). Assessment of virus production and chloramphenicol acetyl transferase expression by insect cells in serum‐free and serum‐supplemented media using a temperature‐sensitive …. Biotechnology And Bioengineering 38 (9), 1091-1099, 1991.
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Mathematical modelling of protein diffusion in microcapsules: A comparison with experimental results

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Mathematical modelling of protein diffusion in microcapsules: A comparison with experimental results. (1991). Mathematical modelling of protein diffusion in microcapsules: A comparison with experimental results. The Canadian Journal Of Chemical Engineering 69 (1), 361-370, 1991.
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Large-scale insect cell culture: methods, applications and products.

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Large-scale insect cell culture: methods, applications and products. (1991). Large-scale insect cell culture: methods, applications and products. Current Opinion In Biotechnology 2 (3), 365-369, 1991.
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Insect cell cultivation techniques for the production of high‐valued products

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Insect cell cultivation techniques for the production of high‐valued products. (1991). Insect cell cultivation techniques for the production of high‐valued products. The Canadian Journal Of Chemical Engineering 69 (2), 450-456, 1991.
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Operation of an Air Lift Reactor for Production of Immunochemicals by Immobilized Hybridoma Cells

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Operation of an Air Lift Reactor for Production of Immunochemicals by Immobilized Hybridoma Cells. (1991). Operation of an Air Lift Reactor for Production of Immunochemicals by Immobilized Hybridoma Cells. Animal Cell Culture And Production Of Biologicals, 135-140, 1991.
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Affinity Separations Using Microcapsules

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Affinity Separations Using Microcapsules. (1990). Affinity Separations Using Microcapsules. Separations For Biotechnology 2, 315-324, 1990.
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Droplet generation

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Droplet generation. (1990). Droplet generation. Us Patent 4,956,128, 1990.
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Kinetics of protein diffusion from a poly (D, L-lactide) reservoir system

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Kinetics of protein diffusion from a poly (D, L-lactide) reservoir system. (1990). Kinetics of protein diffusion from a poly (D, L-lactide) reservoir system. Journal Of Pharmaceutical Sciences 79 (5), 407-410, 1990.
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Vaccines in aquaculture: the search for an efficient delivery system

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Vaccines in aquaculture: the search for an efficient delivery system. (1990). Vaccines in aquaculture: the search for an efficient delivery system. Aquacultural Engineering 9 (1), 23-32, 1990.
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Assessment of chitosan gels for the controlled release of agrochemicals

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Assessment of chitosan gels for the controlled release of agrochemicals. (1990). Assessment of chitosan gels for the controlled release of agrochemicals. Industrial & Engineering Chemistry Research 29 (7), 1205-1209, 1990.
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Multiple membrane microencapsulation

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Multiple membrane microencapsulation. (1990). Multiple membrane microencapsulation. Us Patent 4,942,129, 1990.
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DESIGN AND OPERATION OF AN AIR LIFT REACTOR FOR PRODUCTION OF MONOCLONAL-ANTIBODIES BY IMMOBILIZED HYBRIDOMA CELLS

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DESIGN AND OPERATION OF AN AIR LIFT REACTOR FOR PRODUCTION OF MONOCLONAL-ANTIBODIES BY IMMOBILIZED HYBRIDOMA CELLS. (1990). DESIGN AND OPERATION OF AN AIR LIFT REACTOR FOR PRODUCTION OF MONOCLONAL-ANTIBODIES BY IMMOBILIZED HYBRIDOMA CELLS. Periodicum Biologorum 92 (1), 121-122, 1990.
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Adaptation of insect cells to suspension culture

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Adaptation of insect cells to suspension culture. (1990). Adaptation of insect cells to suspension culture. Journal Of Fermentation And Bioengineering 70 (2), 90-93, 1990.
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Performance of an external loop air-lift bioreactor for the production of monoclonal antibodies by immobilized hybridoma cells

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Performance of an external loop air-lift bioreactor for the production of monoclonal antibodies by immobilized hybridoma cells. (1989). Performance of an external loop air-lift bioreactor for the production of monoclonal antibodies by immobilized hybridoma cells. Applied Microbiology And Biotechnology 30 (3), 264-269, 1989.
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Animal cell culture engineering using alginate polycation microcapsules of controlled membrane molecular weight cut-off

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Animal cell culture engineering using alginate polycation microcapsules of controlled membrane molecular weight cut-off. (1989). Animal cell culture engineering using alginate polycation microcapsules of controlled membrane molecular weight cut-off. Journal Of Membrane Science 41, 323-343, 1989.
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Engineering aspects of insect cell suspension culture: a review

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Engineering aspects of insect cell suspension culture: a review. (1989). Engineering aspects of insect cell suspension culture: a review. Applied Microbiology And Biotechnology 32 (3), 249-255, 1989.
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Toxicity analysis of encapsulation solutions and polymers in the cultivation of insect cells

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Toxicity analysis of encapsulation solutions and polymers in the cultivation of insect cells. (1989). Toxicity analysis of encapsulation solutions and polymers in the cultivation of insect cells. Biotechnology Techniques 3 (1), 61-66, 1989.
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Alginate concentration: a key factor in growth of temperature‐sensitive baculovirus‐infected insect cells in microcapsules

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Alginate concentration: a key factor in growth of temperature‐sensitive baculovirus‐infected insect cells in microcapsules. (1989). Alginate concentration: a key factor in growth of temperature‐sensitive baculovirus‐infected insect cells in microcapsules. Biotechnology And Bioengineering 34 (8), 1085-1091, 1989.
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Delayed release of water-soluble macromolecules from polylactide pellets

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Delayed release of water-soluble macromolecules from polylactide pellets. (1989). Delayed release of water-soluble macromolecules from polylactide pellets. Journal Of Controlled Release 9 (1), 75-85, 1989.
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Growth of baculovirus-infected insect cells in microcapsules to a high cell and virus density

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Growth of baculovirus-infected insect cells in microcapsules to a high cell and virus density. (1988). Growth of baculovirus-infected insect cells in microcapsules to a high cell and virus density. Biotechnology Letters 10 (10), 683-688, 1988.
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Animal cell culture in microcapsules

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Animal cell culture in microcapsules. (1988). Animal cell culture in microcapsules. Chemical Engineering Education 22 (4), 196-200, 1988.
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Microcapsule composition suitable for cardiovascular injection

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Microcapsule composition suitable for cardiovascular injection. (1988). Microcapsule composition suitable for cardiovascular injection. Us Patent 4,789,550, 1988.
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Synthesis of chitosan-alginate microcapsule membranes

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Synthesis of chitosan-alginate microcapsule membranes. (1988). Synthesis of chitosan-alginate microcapsule membranes. Journal Of Bioactive And Compatible Polymers 3 (4), 334-355, 1988.
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Insulin delivery systems and the encapsulation of cells for medical and industrial use

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Insulin delivery systems and the encapsulation of cells for medical and industrial use. (1987). Insulin delivery systems and the encapsulation of cells for medical and industrial use. Crc Critical Reviews In Biocompatibility 3 (1), 1-24, 1987.
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Microencapsulated cells as hormone delivery systems.

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Microencapsulated cells as hormone delivery systems. (1987). Microencapsulated cells as hormone delivery systems. Critical Reviews In Therapeutic Drug Carrier Systems 4 (1), 1-12, 1987.
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Alginate‐polylysine microcapsules of controlled membrane molecular weight cutoff for mammalian cell culture engineering

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Alginate‐polylysine microcapsules of controlled membrane molecular weight cutoff for mammalian cell culture engineering. (1987). Alginate‐polylysine microcapsules of controlled membrane molecular weight cutoff for mammalian cell culture engineering. Biotechnology Progress 3 (4), 231-240, 1987.
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Microencapsulation of living tissue and cells

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Microencapsulation of living tissue and cells. (1987). Microencapsulation of living tissue and cells. Us Patent 4,689,293, 1987.
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Thrombin-Antithrombin III Interactions with a Heparin-Polyvinyl Alcohol Hydrogel

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Thrombin-Antithrombin III Interactions with a Heparin-Polyvinyl Alcohol Hydrogel. (1987). Thrombin-Antithrombin III Interactions with a Heparin-Polyvinyl Alcohol Hydrogel.
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Immobilization of living cells in biocompatible semipermeable microcapsules: biomedical and potential biochemical engineering applications

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Immobilization of living cells in biocompatible semipermeable microcapsules: biomedical and potential biochemical engineering applications. (1986). Immobilization of living cells in biocompatible semipermeable microcapsules: biomedical and potential biochemical engineering applications. Polymers In Medicine Ii, 235-246, 1986.
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In vitro and in vivo release of insulin from poly (lactic acid) microbeads and pellets

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In vitro and in vivo release of insulin from poly (lactic acid) microbeads and pellets. (1986). In vitro and in vivo release of insulin from poly (lactic acid) microbeads and pellets. Journal Of Controlled Release 4 (1), 47-62, 1986.
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Optimization of microencapsulation parameters: semipermeable microcapsules as a bioartificial pancreas

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Optimization of microencapsulation parameters: semipermeable microcapsules as a bioartificial pancreas. (1985). Optimization of microencapsulation parameters: semipermeable microcapsules as a bioartificial pancreas. Biotechnology And Bioengineering 27 (2), 146-150, 1985.
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Slow release injectable insulin composition

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Slow release injectable insulin composition. (1985). Slow release injectable insulin composition. Us Patent 4,492,684, 1985.
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Injectable microencapsulated islet cells as a bioartificial pancreas

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Injectable microencapsulated islet cells as a bioartificial pancreas. (1984). Injectable microencapsulated islet cells as a bioartificial pancreas. Microencapsulation And Artificial Cells, 87-99, 1984.
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Prolonged survival of transplanted islets of Langerhans encapsulated in a biocompatible membrane

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Prolonged survival of transplanted islets of Langerhans encapsulated in a biocompatible membrane. (1984). Prolonged survival of transplanted islets of Langerhans encapsulated in a biocompatible membrane. Biochimica Et Biophysica Acta (Bba)-Molecular Cell Research 804 (1), 133-136, 1984.
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Properties of a heparin‐poly (vinyl alcohol) hydrogel coating

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Properties of a heparin‐poly (vinyl alcohol) hydrogel coating. (1983). Properties of a heparin‐poly (vinyl alcohol) hydrogel coating. Journal Of Biomedical Materials Research 17 (2), 359-373, 1983.
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Microencapsulation of crystalline insulin or islets of Langerhans: an insulin diffusion study

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Microencapsulation of crystalline insulin or islets of Langerhans: an insulin diffusion study. (1983). Microencapsulation of crystalline insulin or islets of Langerhans: an insulin diffusion study. Artificial Organs 7 (2), 208-212, 1983.
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Long-acting insulin: slow release of insulin from a biodegradable matrix implanted in diabetic rats

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Long-acting insulin: slow release of insulin from a biodegradable matrix implanted in diabetic rats. (1983). Long-acting insulin: slow release of insulin from a biodegradable matrix implanted in diabetic rats. Diabetes 32 (5), 478-481, 1983.
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Injectable, biocompatible islet microcapsules as a bioartificial pancreas

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Injectable, biocompatible islet microcapsules as a bioartificial pancreas. (1983). Injectable, biocompatible islet microcapsules as a bioartificial pancreas. Progress In Artificial Organs, 769, 1983.
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Microencapsulation of the islands of Langerhans and the artificial pancreas

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Microencapsulation of the islands of Langerhans and the artificial pancreas. (1982). Microencapsulation of the islands of Langerhans and the artificial pancreas. Journees Annuelles De Diabetologie De L'hotel-Dieu, 161-168, 1982.
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Insulin-albumin microbeads: an implantable, biodegradable system

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Insulin-albumin microbeads: an implantable, biodegradable system. (1982). Insulin-albumin microbeads: an implantable, biodegradable system. Biomaterials, Medical Devices, And Artificial Organs 10 (3), 205-218, 1982.
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The fate of surface bound heparin

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The fate of surface bound heparin. (1982). The fate of surface bound heparin.
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INVALIDATION OF CONCERNS WITH LONG–TERM USE OF HEPARIN: THROMBIN/ANTITHROMBIN III INTERACTIONS

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INVALIDATION OF CONCERNS WITH LONG–TERM USE OF HEPARIN: THROMBIN/ANTITHROMBIN III INTERACTIONS. (1982). INVALIDATION OF CONCERNS WITH LONG–TERM USE OF HEPARIN: THROMBIN/ANTITHROMBIN III INTERACTIONS. Asaio Journal 28 (1), 451-455, 1982.
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Irreversible immobilization of heparin for biomaterials

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Irreversible immobilization of heparin for biomaterials. (1981). Irreversible immobilization of heparin for biomaterials. Dev. Biochem 12 (463), 1981.
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Inactivation of thrombin by antithrombin III on a heparinized biomaterial

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Inactivation of thrombin by antithrombin III on a heparinized biomaterial. (1980). Inactivation of thrombin by antithrombin III on a heparinized biomaterial. Thrombosis Research 20 (5-6), 543-554, 1980.
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Heparin and the inactivation of thrombin by antithrombin III.

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Heparin and the inactivation of thrombin by antithrombin III. (1980). Heparin and the inactivation of thrombin by antithrombin III. Thrombosis Research 17 (1-2), 293-294, 1980.
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Heparinized styrene‐butadiene‐styrene elastomers

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Heparinized styrene‐butadiene‐styrene elastomers. (1979). Heparinized styrene‐butadiene‐styrene elastomers. Journal Of Biomedical Materials Research 13 (3), 347-364, 1979.
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