Dr. Mattheus F.A. Goosen

Associate Vice President for Research & Graduate Studies

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Biodata Mattheus Goosen

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An investigation of the synthesis and thermal stability of poly (DL-lactide)

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An investigation of the synthesis and thermal stability of poly (DL-lactide). (1992). Polymer Bulletin 27 (6), 623-629, 1992.
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Correlation of LDH activity with loss of insect cell viability: An assessment of the LDH assay

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Correlation of LDH activity with loss of insect cell viability: An assessment of the LDH assay. (1992). Biotechnology Techniques 6 (4), 335-340, 1992.
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Fundamentals of animal cell encapsulation and immobilization

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Fundamentals of animal cell encapsulation and immobilization. (1992). CRC Press, 1992.
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Mathematical modelling of protein diffusion in microcapsules: A comparison with experimental results

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Mathematical modelling of protein diffusion in microcapsules: A comparison with experimental results. (1991). The Canadian Journal of Chemical Engineering 69 (1), 361-370, 1991.
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Large-scale insect cell culture: methods, applications and products.

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Large-scale insect cell culture: methods, applications and products. (1991). Current Opinion in Biotechnology 2 (3), 365-369, 1991.
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Insect cell cultivation techniques for the production of high‐valued products

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Insect cell cultivation techniques for the production of high‐valued products. (1991). The Canadian Journal of Chemical Engineering 69 (2), 450-456, 1991.
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Operation of an Air Lift Reactor for Production of Immunochemicals by Immobilized Hybridoma Cells

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Operation of an Air Lift Reactor for Production of Immunochemicals by Immobilized Hybridoma Cells. (1991). Animal Cell Culture and Production of Biologicals, 135-140, 1991.
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Assessment of virus production and chloramphenicol acetyl transferase expression by insect cells in serum‐free and serum‐supplemented media using a temperature‐sensitive …

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Assessment of virus production and chloramphenicol acetyl transferase expression by insect cells in serum‐free and serum‐supplemented media using a temperature‐sensitive …. (1991). Biotechnology and Bioengineering 38 (9), 1091-1099, 1991.
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Adaptation of insect cells to suspension culture

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Adaptation of insect cells to suspension culture. (1990). Journal of Fermentation and Bioengineering 70 (2), 90-93, 1990.
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Affinity Separations Using Microcapsules

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Affinity Separations Using Microcapsules. (1990). Separations for Biotechnology 2, 315-324, 1990.
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Droplet generation

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Droplet generation. (1990). US Patent 4,956,128, 1990.
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Kinetics of protein diffusion from a poly (D, L-lactide) reservoir system

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Kinetics of protein diffusion from a poly (D, L-lactide) reservoir system. (1990). Journal of Pharmaceutical Sciences 79 (5), 407-410, 1990.
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Vaccines in aquaculture: the search for an efficient delivery system

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Vaccines in aquaculture: the search for an efficient delivery system. (1990). Aquacultural Engineering 9 (1), 23-32, 1990.
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Assessment of chitosan gels for the controlled release of agrochemicals

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Assessment of chitosan gels for the controlled release of agrochemicals. (1990). Industrial & Engineering Chemistry Research 29 (7), 1205-1209, 1990.
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Multiple membrane microencapsulation

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Multiple membrane microencapsulation. (1990). US Patent 4,942,129, 1990.
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DESIGN AND OPERATION OF AN AIR LIFT REACTOR FOR PRODUCTION OF MONOCLONAL-ANTIBODIES BY IMMOBILIZED HYBRIDOMA CELLS

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DESIGN AND OPERATION OF AN AIR LIFT REACTOR FOR PRODUCTION OF MONOCLONAL-ANTIBODIES BY IMMOBILIZED HYBRIDOMA CELLS. (1990). PERIODICUM BIOLOGORUM 92 (1), 121-122, 1990.
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Delayed release of water-soluble macromolecules from polylactide pellets

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Delayed release of water-soluble macromolecules from polylactide pellets. (1989). Journal of Controlled Release 9 (1), 75-85, 1989.
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Performance of an external loop air-lift bioreactor for the production of monoclonal antibodies by immobilized hybridoma cells

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Performance of an external loop air-lift bioreactor for the production of monoclonal antibodies by immobilized hybridoma cells. (1989). Applied Microbiology and Biotechnology 30 (3), 264-269, 1989.
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Animal cell culture engineering using alginate polycation microcapsules of controlled membrane molecular weight cut-off

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Animal cell culture engineering using alginate polycation microcapsules of controlled membrane molecular weight cut-off. (1989). Journal of Membrane Science 41, 323-343, 1989.
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Engineering aspects of insect cell suspension culture: a review

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Engineering aspects of insect cell suspension culture: a review. (1989). Applied Microbiology and Biotechnology 32 (3), 249-255, 1989.
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Toxicity analysis of encapsulation solutions and polymers in the cultivation of insect cells

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Toxicity analysis of encapsulation solutions and polymers in the cultivation of insect cells. (1989). Biotechnology Techniques 3 (1), 61-66, 1989.
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Alginate concentration: a key factor in growth of temperature‐sensitive baculovirus‐infected insect cells in microcapsules

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Alginate concentration: a key factor in growth of temperature‐sensitive baculovirus‐infected insect cells in microcapsules. (1989). Biotechnology and Bioengineering 34 (8), 1085-1091, 1989.
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Animal cell culture in microcapsules

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Animal cell culture in microcapsules. (1988). Chemical Engineering Education 22 (4), 196-200, 1988.
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Microcapsule composition suitable for cardiovascular injection

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Microcapsule composition suitable for cardiovascular injection. (1988). US Patent 4,789,550, 1988.
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Synthesis of chitosan-alginate microcapsule membranes

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Synthesis of chitosan-alginate microcapsule membranes. (1988). Journal of Bioactive and Compatible Polymers 3 (4), 334-355, 1988.
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Growth of baculovirus-infected insect cells in microcapsules to a high cell and virus density

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Growth of baculovirus-infected insect cells in microcapsules to a high cell and virus density. (1988). Biotechnology Letters 10 (10), 683-688, 1988.
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Alginate‐polylysine microcapsules of controlled membrane molecular weight cutoff for mammalian cell culture engineering

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Alginate‐polylysine microcapsules of controlled membrane molecular weight cutoff for mammalian cell culture engineering. (1987). Biotechnology Progress 3 (4), 231-240, 1987.
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Microencapsulation of living tissue and cells

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Microencapsulation of living tissue and cells. (1987). US Patent 4,689,293, 1987.
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Thrombin-Antithrombin III Interactions with a Heparin-Polyvinyl Alcohol Hydrogel

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Thrombin-Antithrombin III Interactions with a Heparin-Polyvinyl Alcohol Hydrogel. (1987).
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Insulin delivery systems and the encapsulation of cells for medical and industrial use

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Insulin delivery systems and the encapsulation of cells for medical and industrial use. (1987). CRC Critical Reviews in Biocompatibility 3 (1), 1-24, 1987.
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Microencapsulated cells as hormone delivery systems.

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Microencapsulated cells as hormone delivery systems. (1987). Critical Reviews in Therapeutic Drug Carrier Systems 4 (1), 1-12, 1987.
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Immobilization of living cells in biocompatible semipermeable microcapsules: biomedical and potential biochemical engineering applications

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Immobilization of living cells in biocompatible semipermeable microcapsules: biomedical and potential biochemical engineering applications. (1986). Polymers in Medicine II, 235-246, 1986.
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In vitro and in vivo release of insulin from poly (lactic acid) microbeads and pellets

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In vitro and in vivo release of insulin from poly (lactic acid) microbeads and pellets. (1986). Journal of Controlled Release 4 (1), 47-62, 1986.
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Slow release injectable insulin composition

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Slow release injectable insulin composition. (1985). US Patent 4,492,684, 1985.
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Optimization of microencapsulation parameters: semipermeable microcapsules as a bioartificial pancreas

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Optimization of microencapsulation parameters: semipermeable microcapsules as a bioartificial pancreas. (1985). Biotechnology and Bioengineering 27 (2), 146-150, 1985.
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Injectable microencapsulated islet cells as a bioartificial pancreas

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Injectable microencapsulated islet cells as a bioartificial pancreas. (1984). Microencapsulation and Artificial Cells, 87-99, 1984.
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Prolonged survival of transplanted islets of Langerhans encapsulated in a biocompatible membrane

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Prolonged survival of transplanted islets of Langerhans encapsulated in a biocompatible membrane. (1984). Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 804 (1), 133-136, 1984.
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Long-acting insulin: slow release of insulin from a biodegradable matrix implanted in diabetic rats

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Long-acting insulin: slow release of insulin from a biodegradable matrix implanted in diabetic rats. (1983). Diabetes 32 (5), 478-481, 1983.
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Injectable, biocompatible islet microcapsules as a bioartificial pancreas

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Injectable, biocompatible islet microcapsules as a bioartificial pancreas. (1983). Progress in Artificial Organs, 769, 1983.
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Properties of a heparin‐poly (vinyl alcohol) hydrogel coating

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Properties of a heparin‐poly (vinyl alcohol) hydrogel coating. (1983). Journal of Biomedical Materials Research 17 (2), 359-373, 1983.
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Microencapsulation of crystalline insulin or islets of Langerhans: an insulin diffusion study

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Microencapsulation of crystalline insulin or islets of Langerhans: an insulin diffusion study. (1983). Artificial Organs 7 (2), 208-212, 1983.
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Insulin-albumin microbeads: an implantable, biodegradable system

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Insulin-albumin microbeads: an implantable, biodegradable system. (1982). Biomaterials, Medical Devices, and Artificial Organs 10 (3), 205-218, 1982.
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The fate of surface bound heparin

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The fate of surface bound heparin. (1982).
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INVALIDATION OF CONCERNS WITH LONG–TERM USE OF HEPARIN: THROMBIN/ANTITHROMBIN III INTERACTIONS

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INVALIDATION OF CONCERNS WITH LONG–TERM USE OF HEPARIN: THROMBIN/ANTITHROMBIN III INTERACTIONS. (1982). ASAIO Journal 28 (1), 451-455, 1982.
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Microencapsulation of the islands of Langerhans and the artificial pancreas

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Microencapsulation of the islands of Langerhans and the artificial pancreas. (1982). Journees Annuelles De Diabetologie De L’hotel-Dieu, 161-168, 1982.
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Irreversible immobilization of heparin for biomaterials

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Irreversible immobilization of heparin for biomaterials. (1981). Dev. Biochem 12 (463), 1981.
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Inactivation of thrombin by antithrombin III on a heparinized biomaterial

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Inactivation of thrombin by antithrombin III on a heparinized biomaterial. (1980). Thrombosis Research 20 (5-6), 543-554, 1980.
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Heparin and the inactivation of thrombin by antithrombin III.

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Heparin and the inactivation of thrombin by antithrombin III. (1980). Thrombosis Research 17 (1-2), 293-294, 1980.
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Heparinized styrene‐butadiene‐styrene elastomers

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Heparinized styrene‐butadiene‐styrene elastomers. (1979). Journal of Biomedical Materials Research 13 (3), 347-364, 1979.
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