Dr. Peter Cahusac

Professor, Pharmacology & Biostatistics

Bio

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Bio
Education:
MSc
1992
Pembroke College, Oxford University, UK

Post Doctoral Training
1984
Oxford University, UK

PhD
1984
Bristol University Medical School, UK


BSc Hons
1980
St Andrews University, UK

Awards and Honors:

Physiological Society (London) awards (2007 – 2011), UK
William Ramsay Henderson Trust  Research Grant, Scotland, UK
Nuffield Foundation Grants, UK
Consultant on NIH Grant, University of Arizona, Tucson, USA
Wellcome Trust Travel Grant, Hong Kong
Wellcome Trust Research Grants, UK
Human Frontier Science Program fellowship, University of Arizona, Tucson, USA
European Training Programme Winter School at Zuoz, Switzerland
Royal Society Equipment Grant, UK
Medical Research Council Research Grant, UK
Science and Engineering Research Council (BBSRC) Research Grant, UK
Science and Engineering Research Council (BBSRC) CASE Studentship, UK

 Appointments:

Associate Professor, Alfaisal University 2012-present
Lecturer, University of Stirling, 1994-2012
Research Lecturer, University of Stirling, 1990-1993
Postdoctoral Research Assistant (Medical Research Council), University of Oxford, 1984-1989

Memberships

Fellow of the Royal Statistical Society, GradStat
Member of the British Pharmacological Society
Fellow of the Physiological Society of London

Research Interests:
Statistical inference using the likelihood approach (book).
Neuroscience:  Transmission mechanisms in somatosensory pathways, with specific attention to excitatory amino acid receptors and potassium channels. Electrophysiological methodology in the primary somatosensory (barrel) cortex of the rat and using an in vitro isolated rat vibrissa preparation.
I am currently collaborating with Dr S. Senok, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia, and with Dr Guy Bewick, School of Medical Sciences, University of Aberdeen and Dr Bob Banks, School of Biological and Biomedical Sciences, Durham University.
Current projects:

Mechanosensory lanceolate nerve terminals of mammalian hair follicles, Aberdeen & Durham.
The role of potassium channels in mechanotransduction in slowly adapting mechanoreceptors.
 
Teaching:
Alfaisal University, Riyadh, KSA (since 2012)
Pharmacology lectures contributing to years 1 - 3 medical student blocks
Faculty Advisor for student projects, statistical advisor
Biostatistics, 2nd year medical students block BEP 235
Director of MBS Statistics core course
Director of MBS track Clinical Embryology & Reproductive Biology (2015)
Director of Masters in Applied Research (2020 - )
Member of Clinical Research Committee (King Faisal Specialist Hospital & Research Centre, 2014 - 2018)

University of Stirling, UK (1990-2012)
Chief Examiner and Exams Officer
Contributor to PSY9A4 Brain & Behaviour: clinical perspectives
Coordinator for PSY914 Research Methods
Supervisor for PhD, Master and Undergraduate students

Oxford University, UK (1987-1989)
College tutor in statistics

CV

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Cahusac_CV.pdf (336.27 KB)

Publications

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Effects of camphor and related compounds on slowly adapting mechanoreceptors in the rat sinus hair follicle

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Effects of camphor and related compounds on slowly adapting mechanoreceptors in the rat sinus hair follicle. (2022). IBRO Neuroscience Reports, 2022.

Statistical thinking from scratch: A primer for scientists

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Statistical thinking from scratch: A primer for scientists. (2022). JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 2022.

Estimating sample sizes for evidential t tests

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Estimating sample sizes for evidential t tests. (2022). Research in Mathematics 9 (1), 2089373, 2022.

R Package ‘likelihoodR’

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Cahusac, P. . (2021). R Package ‘likelihoodR’. CRAN.

Clinical Validity Assessment of Integrated Dose Range Checking Tool in a Tertiary Care Hospital Using an Electronic Health Information System

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Clinical Validity Assessment of Integrated Dose Range Checking Tool in a Tertiary Care Hospital Using an Electronic Health Information System. (2021). Hospital Pharmacy 56 (2), 95-101, 2021.

Data as evidence

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Data as evidence. (2020). Experimental Physiology 105 (7), 1071-1080, 2020.

Comparative Analysis of Prescription Drug Prices in South Asian Association for Regional Cooperation Countries

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Comparative Analysis of Prescription Drug Prices in South Asian Association for Regional Cooperation Countries. (2020). Value in Health Regional Issues 21, 113-119, 2020.

Does hyaluronidase enhance drug penetration to mechanoreceptors?

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Does hyaluronidase enhance drug penetration to mechanoreceptors?. (2020). Skin Pharmacology and Physiology 33 (5), 253-260, 2020.

Evidence-Based Statistics: An Introduction to the Evidential Approach-from Likelihood Principle to Statistical Practice

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Evidence-Based Statistics: An Introduction to the Evidential Approach-from Likelihood Principle to Statistical Practice. (2020). John Wiley & Sons, 2020.

Knowledge and use of isotretinoin in Saudi female college students: Cross-sectional study

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Knowledge and use of isotretinoin in Saudi female college students: Cross-sectional study. (2019). Journal of Dermatology and Dermatologic Surgery 23 (2), 76, 2019.

Use of beta blockers is associated with hearing loss

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Use of beta blockers is associated with hearing loss. (2018). International Journal of Audiology 57 (3), 213-220, 2018.

Use of carvedilol is associated with hearing loss

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Use of carvedilol is associated with hearing loss. (2018). Proceedings for Annual Meeting of The Japanese Pharmacological Society …, 2018.

Effects of camel milk in dyslipidaemia: A randomised clinical trial

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Effects of camel milk in dyslipidaemia: A randomised clinical trial. (2018). International Dairy Journal 84, 79-84, 2018.

Selective decline in the prevalence of slowly adapting type I mechanoreceptors during development

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Selective decline in the prevalence of slowly adapting type I mechanoreceptors during development. (2018). International Journal of Developmental Neuroscience 68, 35-38, 2018.

1S, 3R-ACPD

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1S, 3R-ACPD. (2018). Elsevier, 2018.

Institute for Scientific Information-indexed biomedical journals of Saudi Arabia: Their performance from 2007-2014

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Institute for Scientific Information-indexed biomedical journals of Saudi Arabia: Their performance from 2007-2014. (2016). Saudi Medical Journal 37 (11), 1251, 2016.

Combined Recording of Mechanically Stimulated Afferent Output and Nerve Terminal Labelling in Mouse Hair Follicle Lanceolate Endings

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Combined Recording of Mechanically Stimulated Afferent Output and Nerve Terminal Labelling in Mouse Hair Follicle Lanceolate Endings. (2016). JoVE (Journal of Visualized Experiments), e53854, 2016.

Starting out in statistics: An introduction for students of human health, disease, and psychology

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Starting out in statistics: An introduction for students of human health, disease, and psychology. (2014). John Wiley & Sons, 2014.

Glutamatergic modulation of synaptic‐like vesicle recycling in mechanosensory lanceolate nerve terminals of mammalian hair follicles

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Glutamatergic modulation of synaptic‐like vesicle recycling in mechanosensory lanceolate nerve terminals of mammalian hair follicles. (2013). The Journal of Physiology 591 (10), 2523-2540, 2013.

Novel ex vivo preparation to study afferent response pharmacology of guard hair follicles of hairy skin

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Novel ex vivo preparation to study afferent response pharmacology of guard hair follicles of hairy skin. (2013). JOURNAL OF INVESTIGATIVE DERMATOLOGY 133, S82-S82, 2013.

Multiple regression

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Multiple regression. (2010). Physiology News, 12-15, 2010.

Statistical methodology and reporting–the case for confidence intervals

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Statistical methodology and reporting–the case for confidence intervals. (2009). Physiology News, 33-36, 2009.

Non-competitive metabotropic glutamate 1 receptor antagonists block activity of slowly adapting type I mechanoreceptor units in the rat sinus hair follicle

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Non-competitive metabotropic glutamate 1 receptor antagonists block activity of slowly adapting type I mechanoreceptor units in the rat sinus hair follicle. (2009). Neuroscience 163 (3), 933-941, 2009.

Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle

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Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle. (2009). Journal of the Peripheral Nervous System 14 (4), 300-309, 2009.

Glutamate signalling in the skin

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Glutamate signalling in the skin. (2008). Amino Acid Receptor Research (Paley EF, Warfield TE, eds), 125-137, 2008.

A pharmacological study of slowly adapting mechanoreceptors responsive to cold thermal stimulation

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A pharmacological study of slowly adapting mechanoreceptors responsive to cold thermal stimulation. (2007). Neuroscience 148 (2), 489-500, 2007.

Group II metabotropic glutamate receptors reduce excitatory but not inhibitory neurotransmission in rat barrel cortex in vivo

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Group II metabotropic glutamate receptors reduce excitatory but not inhibitory neurotransmission in rat barrel cortex in vivo. (2007). Neuroscience 146 (1), 202-212, 2007.

Behavioural lateralization of tactile performance in the rat

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Behavioural lateralization of tactile performance in the rat. (2007). Physiology & Behavior 91 (2-3), 335-339, 2007.

Enhanced short-latency responses in the ventral posterior medial (VPM) thalamic nucleus following whisker trimming in the adult rat

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Enhanced short-latency responses in the ventral posterior medial (VPM) thalamic nucleus following whisker trimming in the adult rat. (2007). Physiology & Behavior 92 (3), 500-506, 2007.

Potassium channels modulate the mechanical sensitivity of cutaneous type I slowly adapting mechanoreceptors

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Potassium channels modulate the mechanical sensitivity of cutaneous type I slowly adapting mechanoreceptors. (2007). Soc Neurosci Abstr 33 (862.5), 2007.

Metabotropic glutamate receptor antagonists selectively enhance responses of slowly adapting type I mechanoreceptors

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Metabotropic glutamate receptor antagonists selectively enhance responses of slowly adapting type I mechanoreceptors. (2006). Synapse 59 (4), 235-242, 2006.

Decreased sensitivity to self-inflicted pain

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Decreased sensitivity to self-inflicted pain. (2006). Pain 124 (1-2), 134-139, 2006.

Are unconventional NMDA receptors involved in slowly adapting type I mechanoreceptor responses?

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Are unconventional NMDA receptors involved in slowly adapting type I mechanoreceptor responses?. (2005). Neuroscience 133 (3), 763-773, 2005.

Blockade of metabotropic glutamate receptors enhances responses of rat slowly adapting type I cutaneous mechanoreceptors in vitro

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Blockade of metabotropic glutamate receptors enhances responses of rat slowly adapting type I cutaneous mechanoreceptors in vitro. (2005).

Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats

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Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats. (2004). Neuroscience Letters 362 (3), 196-199, 2004.

Cell and Nerve Terminal?

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Cell and Nerve Terminal?. (2003). The Merkel Cell: Structure-Development-Function-Cancerogenesis, 155, 2003.

Glutamate receptor-like immunoreactivity in rat vibrissal Merkel cells

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Glutamate receptor-like immunoreactivity in rat vibrissal Merkel cells. (2003). The Merkel Cell, 163-168, 2003.

The following individuals have been kind enough to serve as ad hoc reviewers for Volume 5

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The following individuals have been kind enough to serve as ad hoc reviewers for Volume 5. (2003). Journal of Alzheimer’s Disease 5 (505), 505, 2003.

Are glutamate receptors involved in transmission at the junction between Merkel cell and nerve terminal?

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Are glutamate receptors involved in transmission at the junction between Merkel cell and nerve terminal?. (2003). The Merkel Cell, 155-162, 2003.

The perception of touch

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The perception of touch. (2002). Signals and Perception: The Fundamentals of Human Sensation. Palgrave Macmillan, 2002.

Right-sided asymmetry in sensitivity to tickle

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Right-sided asymmetry in sensitivity to tickle. (2001). Laterality: Asymmetries of Body, Brain and Cognition 6 (3), 233-238, 2001.

Spontaneous firing in vibrissal type II slowly adapting mechanoreceptors depends on potassium channel activity

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Spontaneous firing in vibrissal type II slowly adapting mechanoreceptors depends on potassium channel activity. (2001). Soc Neurosci Abstr 27 (130.1), 2001.

Evidence for glutamate receptor mediated transmission at mechanoreceptors in the skin

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Evidence for glutamate receptor mediated transmission at mechanoreceptors in the skin. (2001). Neuroreport 12 (2), 341-347, 2001.

MK-801 depression of vibrissal slowly adapting mechanoreceptor responses

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MK-801 depression of vibrissal slowly adapting mechanoreceptor responses. (2001). JOURNAL OF PHYSIOLOGY-LONDON 536, 38P-39P, 2001.

Electrophysiological evidence against a neurotransmitter role of corticotropin-releasing hormone (CRH) in primary somatosensory cortex

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Electrophysiological evidence against a neurotransmitter role of corticotropin-releasing hormone (CRH) in primary somatosensory cortex. (1998). Brain Research 793 (1-2), 73-78, 1998.

Understanding Statistics. An introduction for the Social Sciences

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Understanding Statistics. An introduction for the Social Sciences. (1998). British Journal of Mathematical & Statistical Psychology 51, 185, 1998.

Differential effect of whisker trimming on excitatory and inhibitory transmission in primary somatosensory cortex of the adult rat in vivo

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Differential effect of whisker trimming on excitatory and inhibitory transmission in primary somatosensory cortex of the adult rat in vivo. (1996). Neuroscience 70 (1), 79-92, 1996.

Reduction of NMDA receptor-mediated transmission in the primary somatosensory (SI) cortex following whisker deprivation in the anaesthetized adult rat

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Reduction of NMDA receptor-mediated transmission in the primary somatosensory (SI) cortex following whisker deprivation in the anaesthetized adult rat. (1996). JOURNAL OF PHYSIOLOGY-LONDON 493, P41-P42, 1996.

Synaptic plasticity induced in single neurones of the primary somatosensory cortex in vivo

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Synaptic plasticity induced in single neurones of the primary somatosensory cortex in vivo. (1995). Experimental Brain Research 107 (2), 241-253, 1995.

A pharmacological study of the modulation of neuronal and behavioural nociceptive responses in the rat trigeminal region

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A pharmacological study of the modulation of neuronal and behavioural nociceptive responses in the rat trigeminal region. (1995). Brain Research 700 (1-2), 70-82, 1995.

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