Dr. Peter Cahusac

Professor, Pharmacology & Biostatistics

Bio

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Bio

Education:
MSc
1992
Pembroke College, Oxford University, UK

Post Doctoral Training
1984
Oxford University, UK

PhD
1984
Bristol University Medical School, UK


BSc Hons
1980
St Andrews University, UK

Awards and Honors:

Physiological Society (London) awards (2007 – 2011), UK
William Ramsay Henderson Trust  Research Grant, Scotland, UK
Nuffield Foundation Grants, UK
Consultant on NIH Grant, University of Arizona, Tucson, USA
Wellcome Trust Travel Grant, Hong Kong
Wellcome Trust Research Grants, UK
Human Frontier Science Program fellowship, University of Arizona, Tucson, USA
European Training Programme Winter School at Zuoz, Switzerland
Royal Society Equipment Grant, UK
Medical Research Council Research Grant, UK
Science and Engineering Research Council (BBSRC) Research Grant, UK
Science and Engineering Research Council (BBSRC) CASE Studentship, UK

 Appointments:

Full Professor, Alfaisal University 2023-present
Associate Professor, Alfaisal University 2012-2023
Lecturer, University of Stirling, 1994-2012
Research Lecturer, University of Stirling, 1990-1993
Postdoctoral Research Assistant (Medical Research Council), University of Oxford, 1984-1989

Memberships

Fellow of the Royal Statistical Society, GradStat
Member of the British Pharmacological Society
Fellow of the Physiological Society of London

Research Interests:
Statistical inference using the likelihood approach (book).
Neuroscience:  Transmission mechanisms in somatosensory pathways, with specific attention to excitatory amino acid receptors and potassium channels. Electrophysiological methodology in the primary somatosensory (barrel) cortex of the rat and using an in vitro isolated rat vibrissa preparation.
I am currently collaborating with Dr S. Senok, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia, and with Dr Guy Bewick, School of Medical Sciences, University of Aberdeen and Dr Bob Banks, School of Biological and Biomedical Sciences, Durham University.
Current projects:

Mechanosensory lanceolate nerve terminals of mammalian hair follicles, Aberdeen & Durham.
The role of potassium channels in mechanotransduction in slowly adapting mechanoreceptors.
 
Teaching:
Alfaisal University, Riyadh, KSA (since 2012)
Pharmacology lectures contributing to years 1 - 3 medical student blocks
Faculty Advisor for student projects, statistical advisor
Biostatistics, 2nd year medical students block BEP 235
Director of MBS Statistics core course
Director of MBS track Clinical Embryology & Reproductive Biology (2015)
Director of Masters in Applied Research (2020 - )
Member of Clinical Research Committee (King Faisal Specialist Hospital & Research Centre, 2014 - 2018)

University of Stirling, UK (1990-2012)
Chief Examiner and Exams Officer
Contributor to PSY9A4 Brain & Behaviour: clinical perspectives
Coordinator for PSY914 Research Methods
Supervisor for PhD, Master and Undergraduate students

Oxford University, UK (1987-1989)
College tutor in statistics

CV

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Cahusac_CV.pdf (324.44 KB)

Publications

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Evidence for glutamate receptor mediated transmission at mechanoreceptors in the skin

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Evidence for glutamate receptor mediated transmission at mechanoreceptors in the skin. (2001). Neuroreport 12 (2), 341-347, 2001.

MK-801 depression of vibrissal slowly adapting mechanoreceptor responses

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MK-801 depression of vibrissal slowly adapting mechanoreceptor responses. (2001). JOURNAL OF PHYSIOLOGY-LONDON 536, 38P-39P, 2001.

Right-sided asymmetry in sensitivity to tickle

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Right-sided asymmetry in sensitivity to tickle. (2001). Laterality: Asymmetries of Body, Brain and Cognition 6 (3), 233-238, 2001.

Understanding Statistics. An introduction for the Social Sciences

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Understanding Statistics. An introduction for the Social Sciences. (1998). British Journal of Mathematical & Statistical Psychology 51, 185, 1998.

Electrophysiological evidence against a neurotransmitter role of corticotropin-releasing hormone (CRH) in primary somatosensory cortex

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Electrophysiological evidence against a neurotransmitter role of corticotropin-releasing hormone (CRH) in primary somatosensory cortex. (1998). Brain Research 793 (1-2), 73-78, 1998.

Reduction of NMDA receptor-mediated transmission in the primary somatosensory (SI) cortex following whisker deprivation in the anaesthetized adult rat

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Reduction of NMDA receptor-mediated transmission in the primary somatosensory (SI) cortex following whisker deprivation in the anaesthetized adult rat. (1996). JOURNAL OF PHYSIOLOGY-LONDON 493, P41-P42, 1996.

Differential effect of whisker trimming on excitatory and inhibitory transmission in primary somatosensory cortex of the adult rat in vivo

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Differential effect of whisker trimming on excitatory and inhibitory transmission in primary somatosensory cortex of the adult rat in vivo. (1996). Neuroscience 70 (1), 79-92, 1996.

The effects of L-AP4 and L-serine-O-phosphate on inhibition in primary somatosensory cortex of the adult rat in vivo

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The effects of L-AP4 and L-serine-O-phosphate on inhibition in primary somatosensory cortex of the adult rat in vivo. (1995). Neuropharmacology 34 (8), 1053-1062, 1995.

Synaptic plasticity induced in single neurones of the primary somatosensory cortex in vivo

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Synaptic plasticity induced in single neurones of the primary somatosensory cortex in vivo. (1995). Experimental Brain Research 107 (2), 241-253, 1995.

A pharmacological study of the modulation of neuronal and behavioural nociceptive responses in the rat trigeminal region

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A pharmacological study of the modulation of neuronal and behavioural nociceptive responses in the rat trigeminal region. (1995). Brain Research 700 (1-2), 70-82, 1995.

L (+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID (L-AP4) CAUSES DISINHIBITION OF NEURONAL RESPONSES IN PRIMARY SOMATOSENSORY (SI) CORTEX OF THE URETHANE-ANESTHETIZED ADULT-RAT

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L (+)-2-AMINO-4-PHOSPHONOBUTYRIC ACID (L-AP4) CAUSES DISINHIBITION OF NEURONAL RESPONSES IN PRIMARY SOMATOSENSORY (SI) CORTEX OF THE URETHANE-ANESTHETIZED ADULT-RAT. (1995). JOURNAL OF PHYSIOLOGY-LONDON 483, P155-P156, 1995.

EXCITATORY AND DEPRESSANT EFFECTS OF THE METABOTROPIC GLUTAMATE-RECEPTOR AGONIST 1S, 3R-ACPD ON NEURONAL FIRING IN RAT PRIMARY SOMATOSENSORY CORTEX IN-VIVO

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EXCITATORY AND DEPRESSANT EFFECTS OF THE METABOTROPIC GLUTAMATE-RECEPTOR AGONIST 1S, 3R-ACPD ON NEURONAL FIRING IN RAT PRIMARY SOMATOSENSORY CORTEX IN-VIVO. (1994). JOURNAL OF PHYSIOLOGY-LONDON 476, P72-P73, 1994.

The effects of the metabotropic glutamate receptor agonist 1S, 3R-ACPD on neurones in the rat primary somatosensory cortex in vivo

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The effects of the metabotropic glutamate receptor agonist 1S, 3R-ACPD on neurones in the rat primary somatosensory cortex in vivo. (1994). Neuropharmacology 33 (1), 103-108, 1994.

Cortical layer‐specific effects of the metabotropic glutamate receptor agonist 1S, 3R‐ACPD in rat primary somatosensory cortex in vivo

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Cortical layer‐specific effects of the metabotropic glutamate receptor agonist 1S, 3R‐ACPD in rat primary somatosensory cortex in vivo. (1994). European Journal of Neuroscience 6 (9), 1505-1511, 1994.

Synaptic plasticity induced by pairing vibrissal-evoked neuronal responses with iontophoretic glutamate in the primary somatosensory cortex of the anaesthetized rat

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Synaptic plasticity induced by pairing vibrissal-evoked neuronal responses with iontophoretic glutamate in the primary somatosensory cortex of the anaesthetized rat. (1993). JOURNAL OF PHYSIOLOGY-LONDON THEN CAMBRIDGE- 1 (467), 92-92, 1993.

Modification of the responses of hippocampal neurons in the monkey during the learning of a conditional spatial response task

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Modification of the responses of hippocampal neurons in the monkey during the learning of a conditional spatial response task. (1993). Hippocampus 3 (1), 29-42, 1993.

Responses of single neurons in the hippocampus of the macaque related to recognition memory

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Responses of single neurons in the hippocampus of the macaque related to recognition memory. (1993). Experimental Brain Research 93 (2), 299-306, 1993.

Potentiation of neuronal responses to natural visual input paired with postsynaptic activation in the hippocampus of the awake monkey

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Potentiation of neuronal responses to natural visual input paired with postsynaptic activation in the hippocampus of the awake monkey. (1991). Neuroscience Letters 124 (1), 39-43, 1991.

MODIFICATIONS OF NEURONAL RESPONSES TO NATURAL INPUTS PAIRED WITH ACTIVATION OF THE POSTSYNAPTIC NEURON BY IONOPHORETIC L-GLUTAMATE IN THE MACAQUE HIPPOCAMPUS

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MODIFICATIONS OF NEURONAL RESPONSES TO NATURAL INPUTS PAIRED WITH ACTIVATION OF THE POSTSYNAPTIC NEURON BY IONOPHORETIC L-GLUTAMATE IN THE MACAQUE HIPPOCAMPUS. (1990). JOURNAL OF PHYSIOLOGY-LONDON 420, P45-P45, 1990.

Sensory responses of caudal trigeminal neurons to thermal and mechanical stimuli and their behavioural correlates in the rat

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Sensory responses of caudal trigeminal neurons to thermal and mechanical stimuli and their behavioural correlates in the rat. (1990). Neuroscience 36 (2), 543-551, 1990.

Responses of hippocampal formation neurons in the monkey related to delayed spatial response and object-place memory tasks

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Responses of hippocampal formation neurons in the monkey related to delayed spatial response and object-place memory tasks. (1989). Behavioural Brain Research 33 (3), 229-240, 1989.

Activity of hippocampal formation neurons in the monkey related to a conditional spatial response task

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Activity of hippocampal formation neurons in the monkey related to a conditional spatial response task. (1989). Journal of Neurophysiology 61 (3), 669-678, 1989.

Activity of hippocampal neurons in the monkey related to a conditional response task

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Activity of hippocampal neurons in the monkey related to a conditional response task. (1989). Neurophysiol, 1989.

Modification of hippocampal neuronal responses during the learning of a conditional response task in the monkey

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Modification of hippocampal neuronal responses during the learning of a conditional response task in the monkey. (1989). Preparation, 1989.

Hippocampal neurons in the monkey with activity related to the place in which a stimulus is shown

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Hippocampal neurons in the monkey with activity related to the place in which a stimulus is shown. (1989). Journal of Neuroscience 9 (6), 1835-1845, 1989.

Activity of hippocampal formation neurons in the monkey related to a stimulus-response association task

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Activity of hippocampal formation neurons in the monkey related to a stimulus-response association task. (1989). Journal of Neurophysiology 61, 669-678, 1989.

Hippocampal activity related to the processing of single sensory-motor associations

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Hippocampal activity related to the processing of single sensory-motor associations. (1988). Neuroscience Letters 90 (3), 265-272, 1988.

A comparative study of responsive neurons in different subareas of the primate hippocampal formation

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A comparative study of responsive neurons in different subareas of the primate hippocampal formation. (1987). Neurosci. Lett 29, 103, 1987.

The coding of spatial information by neurons in the primate hippocampal formation

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The coding of spatial information by neurons in the primate hippocampal formation. (1987). Society for Neuroscience Abstracts 13, 608, 1987.

Functions of the primate hippocampus: Neurophysiological evidence

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Functions of the primate hippocampus: Neurophysiological evidence. (1986). Behavioural Brain Research 20 (1), 139, 1986.

Neuronal activity in the parahippocampal gyrus of the behaving primate

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Neuronal activity in the parahippocampal gyrus of the behaving primate. (1986). International Congress of Neuroethology Abstracts 1, 83, 1986.

Modifications of neuronal activity during learning in the primate hippocampus

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Modifications of neuronal activity during learning in the primate hippocampus. (1986). Neuroscience Let-Ters, S24, S29, 1986.

The responses of single neurons in the primate hippocampus related to the performance of memory tasks

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The responses of single neurons in the primate hippocampus related to the performance of memory tasks. (1985). Socictvfor Neuroscicnce Abstracts 11, 525, 1985.

Kodriquez. RE and Smith. DAS, The behavioural effects of an hr-methylaspartate receptor antagonist following application lo the lumbar spinal cord of conscious rats

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Kodriquez. RE and Smith. DAS, The behavioural effects of an hr-methylaspartate receptor antagonist following application lo the lumbar spinal cord of conscious rats. (1984). Neuropharmacology 23, 719-724, 1984.

A behavioural and neuropharmacological study of the modulation of trigeminal nociception in the rat

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A behavioural and neuropharmacological study of the modulation of trigeminal nociception in the rat. (1984). University of Bristol, 1984.

CORRELATIONS BETWEEN NEURONAL AND BEHAVIORAL-RESPONSES IN THE RAT TRIGEMINAL REGION FOLLOWING PERIVENTRICULAR STIMULATION

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CORRELATIONS BETWEEN NEURONAL AND BEHAVIORAL-RESPONSES IN THE RAT TRIGEMINAL REGION FOLLOWING PERIVENTRICULAR STIMULATION. (1984). JOURNAL OF PHYSIOLOGY-LONDON 346 (JAN), P47-P47, 1984.

The effects of microiontophoretically-applied opioids and opiate antagonists on nociceptive responses of neurones of the caudal reticular formation in the rat

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The effects of microiontophoretically-applied opioids and opiate antagonists on nociceptive responses of neurones of the caudal reticular formation in the rat. (1984). Neuropharmacology 23 (5), 497-504, 1984.

The behavioural effects of an N-methylaspartate receptor antagonist following application to the lumbar spinal cord of conscious rats

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The behavioural effects of an N-methylaspartate receptor antagonist following application to the lumbar spinal cord of conscious rats. (1984). Neuropharmacology 23 (7), 719-724, 1984.

Alpha-2 adrenergic receptors on neurones in the region of the lateral reticular nucleus of the rat

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Alpha-2 adrenergic receptors on neurones in the region of the lateral reticular nucleus of the rat. (1983). Neuroscience Letters 42 (3), 279-284, 1983.

Response characteristics of rat caudal trigeminal neurons to thermal stimuli

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Response characteristics of rat caudal trigeminal neurons to thermal stimuli. (1983). JOURNAL OF PHYSIOLOGY-LONDON 345 (DEC), P21-P21, 1983.

The behavioural effects of intrathecally administered [D-PRO2, D-TRP7, 9]-substance P, an analogue with presumed antagonist actions, in the rat

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The behavioural effects of intrathecally administered [D-PRO2, D-TRP7, 9]-substance P, an analogue with presumed antagonist actions, in the rat. (1983). Neuropharmacology 22 (2), 173-176, 1983.

THE EFFECTS OF MICROIONOPHORETIC APPLICATION OF MONOAMINES ON SENSORY NEURONS OF THE RAT CAUDAL TRIGEMINAL NUCLEUS

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THE EFFECTS OF MICROIONOPHORETIC APPLICATION OF MONOAMINES ON SENSORY NEURONS OF THE RAT CAUDAL TRIGEMINAL NUCLEUS. (1983). JOURNAL OF PHYSIOLOGY-LONDON 338 (MAY), P38-P39, 1983.

The behavioural effects of intrathecally administered [D-Pro2, D-Trp7, 9] substance P, an analogue with presumed antagonistic actions, in the rat

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The behavioural effects of intrathecally administered [D-Pro2, D-Trp7, 9] substance P, an analogue with presumed antagonistic actions, in the rat. (1983). Neuropharmacology 22, 173-176, 1983.

INTRATHECAL ADMINISTRATION OF AN EXCITANT AMINO-ACID RECEPTOR ANTAGONIST IN THE CONSCIOUS RAT

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INTRATHECAL ADMINISTRATION OF AN EXCITANT AMINO-ACID RECEPTOR ANTAGONIST IN THE CONSCIOUS RAT. (1983). JOURNAL OF PHYSIOLOGY-LONDON 334 (JAN), P90-P91, 1983.

Evaluation of (d-Pro2, d-Trp7, 9)-substance P as an antagonist of substance P responses in the rat central nervous system

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Evaluation of (d-Pro2, d-Trp7, 9)-substance P as an antagonist of substance P responses in the rat central nervous system. (1982). Neuroscience Letters 30 (3), 291-295, 1982.

using water at 50 C. The measured response in this test was the time period

Journal Article ,
using water at 50 C. The measured response in this test was the time period. (1982). Anatomical, Physiological, and Pharmacological Aspects of Trigeminal Pain …, 1982.

The involvement of endogenous opioids in the descending inhibition of caudal trigeminal and reticular nociceptive neurones evoked by analgesia-producing periaqueductal grey …

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The involvement of endogenous opioids in the descending inhibition of caudal trigeminal and reticular nociceptive neurones evoked by analgesia-producing periaqueductal grey …. (1982). Anatomical, Physiological and Pharmacological Aspects of Trigeminal Pain …, 1982.

METHODS FOR INVESTIGATION OF THE LOCOMOTOR BEHAVIOR AND ELEVATION OF NOCICEPTIVE REFLEX THRESHOLD EVOKED BY PERIAQUEDUCTAL GREY (PAG) STIMULATION IN THE FREELY MOVING RAT

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METHODS FOR INVESTIGATION OF THE LOCOMOTOR BEHAVIOR AND ELEVATION OF NOCICEPTIVE REFLEX THRESHOLD EVOKED BY PERIAQUEDUCTAL GREY (PAG) STIMULATION IN THE FREELY MOVING RAT. (1982). J PHYSIOL-LONDON 327 (JUN), P20-P21, 1982.

A behavioural model for the study of facial nociception and the effects of descending modulatory systems in the rat

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A behavioural model for the study of facial nociception and the effects of descending modulatory systems in the rat. (1982). Journal of Neuroscience Methods 6 (3), 245-252, 1982.

Behavioural and electrophysiological studies related to nociception in capsaicintreated rats

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Behavioural and electrophysiological studies related to nociception in capsaicintreated rats. (1982). Anatomical, Physiological, and Pharmacological Aspects of Trigeminal Pain …, 1982.

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