Dr. Raja Chinnappan| Alfaisal Faculty

Dr. Raja Chinnappan

Lecturer of Biochemistry and Molecular Medicine

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RajaChinnappan-CV.pdf (260.45 KB)

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Molecular engineering of a fluorescent probe for highly efficient detection of human serum albumin in biological fluid

Journal Article Tue, 10/15/2024 - 20:57 ,

Molecular engineering of a fluorescent probe for highly efficient detection of human serum albumin in biological fluid. (2024). Sensors International.

Google scholar Link

https://doi.org/10.1016/j.sintl.2024.100304.

Bio-analysis of Saliva Using Paper Devices and Colorimetric Assays

Journal Article Tue, 10/15/2024 - 20:43 ,

Bio-analysis of Saliva Using Paper Devices and Colorimetric Assays. (2024). Journal of Analysis and Testing.

Google scholar Link

https://link.springer.com/article/10.1007/s41664-023-00282-y

Bioengineered Organoids Offer New Possibilities for Liver Cancer Studies: A Review of Key Milestones and Challenges

Journal Article Tue, 10/15/2024 - 20:45 ,

Bioengineered Organoids Offer New Possibilities for Liver Cancer Studies: A Review of Key Milestones and Challenges. (2024). Bioengineering.

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https://www.mdpi.com/2306-5354/11/4/346

Rapid Colorimetric Quantita2tive Portable Platform for Detection of Brucella melitensis Based on a Fluorescence Resonance Energy Transfer Assay and Nanomagnetic Particles

Journal Article Tue, 10/15/2024 - 20:48 ,

Rapid Colorimetric Quantita2tive Portable Platform for Detection of Brucella melitensis Based on a Fluorescence Resonance Energy Transfer Assay and Nanomagnetic Particles. (2024). ACS Omega.

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https://pubs.acs.org/doi/10.1021/acsomega.4c00192

Biosensing of Alpha-Fetoprotein: A Key Direction toward the Early Detection and Management of Hepatocellular Carcinoma

Journal Article Tue, 10/15/2024 - 20:49 ,

Biosensing of Alpha-Fetoprotein: A Key Direction toward the Early Detection and Management of Hepatocellular Carcinoma. (2024). Biosensors.

Google scholar Link

https://www.mdpi.com/2079-6374/14/5/235

Emerging role of exosomal microRNA in liver cancer in the era of precision medicine; potential and challenges

Journal Article Tue, 10/15/2024 - 20:50 ,

Emerging role of exosomal microRNA in liver cancer in the era of precision medicine; potential and challenges. (2024). Frontiers in Molecular Biosciences.

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https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmo…

Recent Advances in Biosensor Technology for Early-Stage Detection of Hepatocellular Carcinoma-Specific Biomarkers: An Overview

Journal Article Tue, 10/15/2024 - 20:52 ,

Recent Advances in Biosensor Technology for Early-Stage Detection of Hepatocellular Carcinoma-Specific Biomarkers: An Overview. (2024). Diagnostics.

Google scholar Link

https://www.mdpi.com/2075-4418/14/14/1519

A review of current state-of-the-art materiobiology and technological approaches for liver tissue engineering

Journal Article Tue, 10/15/2024 - 20:54 ,

A review of current state-of-the-art materiobiology and technological approaches for liver tissue engineering. (2024). Bioprinting.

Google scholar Link

https://www.sciencedirect.com/science/article/abs/pii/S2405886624000277

Development of highly porous seaweed impregnated facemask substrates for protecting people from microbial hazards

Journal Article Tue, 10/15/2024 - 20:55 ,

Development of highly porous seaweed impregnated facemask substrates for protecting people from microbial hazards. (2024). Environmental Technology & Innovation.

Google scholar Link

https://www.sciencedirect.com/science/article/pii/S2352186424002402

An integrated lab-on-a-chip platform for pre-concentration and detection of colorectal cancer exosomes using anti-CD63 aptamer as a recognition element

Journal Article Tue, 10/15/2024 - 20:19 ,

An integrated lab-on-a-chip platform for pre-concentration and detection of colorectal cancer exosomes using anti-CD63 aptamer as a recognition element. (2023). Biosensors and Bioelectronics.

Google scholar Link

https://www.sciencedirect.com/science/article/abs/pii/S095656632200896X

Aptasensors are conjectured as promising ALT and AST diagnostic tools for the early diagnosis of acute liver injury

Journal Article Tue, 10/15/2024 - 20:22 ,

Aptasensors are conjectured as promising ALT and AST diagnostic tools for the early diagnosis of acute liver injury. (2023). Life.

Google scholar Link

https://www.mdpi.com/2075-1729/13/6/1273

Emerging biosensing methods to monitor lung cancer biomarkers in biological samples: a comprehensive review

Journal Article Tue, 10/15/2024 - 20:27 ,

Emerging biosensing methods to monitor lung cancer biomarkers in biological samples: a comprehensive review. (2023). Cancers.

Google scholar Link

https://www.mdpi.com/2072-6694/15/13/3414

Isolation and Detection of Exosomal Mir210 Using Carbon Nanomaterial-Coated Magnetic Beads

Journal Article Tue, 10/15/2024 - 20:28 ,

Isolation and Detection of Exosomal Mir210 Using Carbon Nanomaterial-Coated Magnetic Beads. (2023). J. Funct. Biomater.

Google scholar Link

https://www.mdpi.com/2079-4983/14/9/441

Low-cost point-of-care monitoring of ALT and AST is promising for faster decision making and diagnosis of acute liver injury

Journal Article Tue, 10/15/2024 - 20:30 ,

Low-cost point-of-care monitoring of ALT and AST is promising for faster decision making and diagnosis of acute liver injury. (2023). Diagnostics.

Google scholar Link

https://www.mdpi.com/2075-4418/13/18/2967

Tuning hydrophobicity of paper substrates for effective colorimetric detection of glucose and nucleic acids

Journal Article Tue, 10/15/2024 - 20:33 ,

Tuning hydrophobicity of paper substrates for effective colorimetric detection of glucose and nucleic acids. (2023). Analytical and Bioanalytical Chemistry.

Google scholar Link

https://link.springer.com/article/10.1007/s00216-023-04921-2

A Hypothetical Approach to Concentrate Microorganisms from Human Urine Samples Using Paper-Based Adsorbents for Point-of-Care Molecular Assays

Journal Article Tue, 10/15/2024 - 20:42 ,

A Hypothetical Approach to Concentrate Microorganisms from Human Urine Samples Using Paper-Based Adsorbents for Point-of-Care Molecular Assays. (2023). Life.

Google scholar Link

https://www.mdpi.com/2075-1729/14/1/38

Advances in biosensing technologies for diagnosis of COVID-19

Journal Article Tue, 10/15/2024 - 20:17 ,

Advances in biosensing technologies for diagnosis of COVID-19. (2022). Biosensors.

Google scholar Link

https://www.mdpi.com/2079-6374/12/10/898

Exploring the Utility of ssDNA Aptamers Directed against Snake Venom Toxins as New Therapeutics for Snakebite Envenoming

Journal Article Tue, 08/09/2022 - 11:57 ,

Exploring the Utility of ssDNA Aptamers Directed against Snake Venom Toxins as New Therapeutics for Snakebite Envenoming. (2022). Toxins 14 (7), 469, 2022.

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https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Exploring the utility of ssDNA aptamers directed against snake venom toxins as new therapeutics for tropical snakebite envenoming

Journal Article Tue, 08/09/2022 - 11:57 ,

Exploring the utility of ssDNA aptamers directed against snake venom toxins as new therapeutics for tropical snakebite envenoming. (2022). BioRxiv, 2022.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Aptamers: Potential Diagnostic and Therapeutic Agents for Blood Diseases

Journal Article Mon, 08/08/2022 - 17:05 ,

Aptamers: Potential Diagnostic and Therapeutic Agents for Blood Diseases. (2022). Molecules 27 (2), 383, 2022.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Highly sensitive and selective lateral flow aptasensor for anti-coagulant dabigatran etexilate determination in blood

Journal Article Tue, 08/09/2022 - 11:57 ,

Highly sensitive and selective lateral flow aptasensor for anti-coagulant dabigatran etexilate determination in blood. (2022). Talanta 236, 122887, 2022.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Aptamer selection and aptasensor construction for bone density biomarkers

Journal Article Tue, 08/09/2022 - 11:57 ,

Aptamer selection and aptasensor construction for bone density biomarkers. (2021). Talanta 224, 121818, 2021.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Determination of minimal sequence for zearalenone aptamer by computational docking and application on an indirect competitive electrochemical aptasensor

Journal Article Mon, 07/18/2022 - 15:03 ,

Determination of minimal sequence for zearalenone aptamer by computational docking and application on an indirect competitive electrochemical aptasensor. (2021). Analytical and Bioanalytical Chemistry 413 (15), 3861-3872, 2021.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Peptide substrate screening for the diagnosis of SARS-CoV-2 using fluorescence resonance energy transfer (FRET) assay

Journal Article Tue, 08/09/2022 - 11:57 ,

Peptide substrate screening for the diagnosis of SARS-CoV-2 using fluorescence resonance energy transfer (FRET) assay. (2021). Microchimica Acta 188 (4), 1-10, 2021.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Low-cost colorimetric diagnostic screening assay for methicillin resistant Staphylococcus aureus

Journal Article Mon, 07/18/2022 - 15:03 ,

Low-cost colorimetric diagnostic screening assay for methicillin resistant Staphylococcus aureus. (2021). Talanta 225, 121946, 2021.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Simple and rapid peptide nanoprobe biosensor for the detection of Legionellaceae

Journal Article Mon, 08/08/2022 - 17:05 ,

Simple and rapid peptide nanoprobe biosensor for the detection of Legionellaceae. (2021). Analyst 146 (11), 3568-3577, 2021.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Aptameric biosensor for the sensitive detection of major shrimp allergen, tropomyosin

Journal Article Tue, 08/09/2022 - 11:57 ,

Aptameric biosensor for the sensitive detection of major shrimp allergen, tropomyosin. (2020). Food Chemistry 314, 126133, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

In vitro selection of DNA aptamers and their integration in a competitive voltammetric biosensor for azlocillin determination in waste water

Journal Article Mon, 07/18/2022 - 15:03 ,

In vitro selection of DNA aptamers and their integration in a competitive voltammetric biosensor for azlocillin determination in waste water. (2020). Analytica Chimica Acta 1101, 149-156, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Selection, characterization, and electrochemical biosensing application of DNA aptamers for sepiapterin

Journal Article Mon, 07/18/2022 - 15:03 ,

Selection, characterization, and electrochemical biosensing application of DNA aptamers for sepiapterin. (2020). Talanta 216, 120951, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Development of a simple, fast, and cost-effective nanobased immunoassay method for detecting Norovirus in food samples

Journal Article Tue, 08/09/2022 - 11:57 ,

Development of a simple, fast, and cost-effective nanobased immunoassay method for detecting Norovirus in food samples. (2020). Acs Omega 5 (21), 12162-12165, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Probing high-affinity aptamer binding region and development of aptasensor platform for the detection of cylindrospermopsin

Journal Article Tue, 08/09/2022 - 11:57 ,

Probing high-affinity aptamer binding region and development of aptasensor platform for the detection of cylindrospermopsin. (2020). Analytical and Bioanalytical Chemistry 412 (19), 4691-4701, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Full-length and truncated anti-coagulant Dabigatran etexilate specific DNA aptamers for electrochemical and fluorescence sensing applications

Journal Article Mon, 07/18/2022 - 15:03 ,

Full-length and truncated anti-coagulant Dabigatran etexilate specific DNA aptamers for electrochemical and fluorescence sensing applications. (2020). US Patent 10,788,488, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Anti-VCAM-1 and Anti-IL4Rα aptamer-conjugated super paramagnetic iron oxide nanoparticles for enhanced breast cancer diagnosis and therapy

Journal Article Tue, 08/09/2022 - 11:57 ,

Anti-VCAM-1 and Anti-IL4Rα aptamer-conjugated super paramagnetic iron oxide nanoparticles for enhanced breast cancer diagnosis and therapy. (2020). Molecules 25 (15), 3437, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Mapping the binding region of aptamer targeting small molecule: Dabigatran etexilate, an anti-coagulant

Journal Article Tue, 08/09/2022 - 11:57 ,

Mapping the binding region of aptamer targeting small molecule: Dabigatran etexilate, an anti-coagulant. (2020). Talanta 218, 121132, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Electrochemical determination of zearalenone using a label-free competitive aptasensor

Journal Article Mon, 07/18/2022 - 15:03 ,

Electrochemical determination of zearalenone using a label-free competitive aptasensor. (2020). Microchimica Acta 187 (5), 1-10, 2020.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Electrochemical SELEX technique for the selection of DNA aptamers against the small molecule 11-deoxycortisol

Journal Article Mon, 07/18/2022 - 15:03 ,

Electrochemical SELEX technique for the selection of DNA aptamers against the small molecule 11-deoxycortisol. (2019). ACS Applied Bio Materials 2 (6), 2624-2632, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

An aptamer based fluorometric microcystin-LR assay using DNA strand-based competitive displacement

Journal Article Tue, 08/09/2022 - 11:57 ,

An aptamer based fluorometric microcystin-LR assay using DNA strand-based competitive displacement. (2019). Microchimica Acta 186 (7), 1-10, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Highly sensitive multiplex detection of microRNA by competitive DNA strand displacement fluorescence assay

Journal Article Tue, 08/09/2022 - 11:57 ,

Highly sensitive multiplex detection of microRNA by competitive DNA strand displacement fluorescence assay. (2019). Talanta 200, 487-493, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Electrochemical selection of a DNA aptamer, and an impedimetric method for determination of the dedicator of cytokinesis 8 by self-assembly of a thiolated aptamer on a gold …

Journal Article Mon, 07/18/2022 - 15:03 ,

Electrochemical selection of a DNA aptamer, and an impedimetric method for determination of the dedicator of cytokinesis 8 by self-assembly of a thiolated aptamer on a gold …. (2019). Microchimica Acta 186 (12), 1-9, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Electrochemical screening for the selection of DNA aptamers

Journal Article Mon, 07/18/2022 - 15:03 ,

Electrochemical screening for the selection of DNA aptamers. (2019). US Patent 10,520,462, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Fluorometric determination of okadaic acid using a truncated aptamer

Journal Article Mon, 07/11/2022 - 12:19 ,

Fluorometric determination of okadaic acid using a truncated aptamer. (2019). Microchimica Acta 186 (7), 1-9, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Studies on the dynamics of fluorophore bound macromolecules and their self organisation behaviour in aqueous solutions

Journal Article Tue, 10/18/2022 - 11:23 ,

Studies on the dynamics of fluorophore bound macromolecules and their self organisation behaviour in aqueous solutions. (2019). University of Madras, Chennai, India, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Early detection of lung cancer biomarkers through biosensor technology: A review

Journal Article Tue, 10/18/2022 - 11:23 ,

Early detection of lung cancer biomarkers through biosensor technology: A review. (2019). Journal of Pharmaceutical and Biomedical Analysis 164, 93-103, 2019.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

In vitro selection of specific dna aptamers against the anti-coagulant dabigatran etexilate

Journal Article Mon, 07/18/2022 - 15:03 ,

In vitro selection of specific dna aptamers against the anti-coagulant dabigatran etexilate. (2018). Scientific Reports 8 (1), 1-8, 2018.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Rapid colorimetric lactoferrin-based sandwich immunoassay on cotton swabs for the detection of foodborne pathogenic bacteria

Journal Article Mon, 07/11/2022 - 12:19 ,

Rapid colorimetric lactoferrin-based sandwich immunoassay on cotton swabs for the detection of foodborne pathogenic bacteria. (2018). Talanta 185, 275-280, 2018.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Fluorometric graphene oxide-based detection of Salmonella enteritis using a truncated DNA aptamer

Journal Article Mon, 07/11/2022 - 12:19 ,

Fluorometric graphene oxide-based detection of Salmonella enteritis using a truncated DNA aptamer. (2018). Microchimica Acta 185 (1), 1-9, 2018.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

A rapid colorimetric immunoassay for the detection of pathogenic bacteria on poultry processing plants using cotton swabs and nanobeads

Journal Article Mon, 07/18/2022 - 15:03 ,

A rapid colorimetric immunoassay for the detection of pathogenic bacteria on poultry processing plants using cotton swabs and nanobeads. (2018). Microchimica Acta 185 (3), 1-10, 2018.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Development of Novel Nanobiosensor for Direct Measurement of the Oral Anticoagulant Agent: Dabigatran Etexilate

Journal Article Tue, 08/09/2022 - 11:57 ,

Development of Novel Nanobiosensor for Direct Measurement of the Oral Anticoagulant Agent: Dabigatran Etexilate. (2018). Blood 132 (Suppl 1), 1247-1247, 2018.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Development of magnetic nanoparticle based calorimetric assay for the detection of bovine mastitis in cow milk

Journal Article Tue, 08/09/2022 - 11:57 ,

Development of magnetic nanoparticle based calorimetric assay for the detection of bovine mastitis in cow milk. (2017). Analytical Biochemistry 523, 58-64, 2017.

Google scholar Link

https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

Ultrasensitive Label‐free Electrochemical Immunosensors for Multiple Cell Surface Biomarkers on Liver Cancer Stem Cells

Journal Article Mon, 07/18/2022 - 15:03 ,

Ultrasensitive Label‐free Electrochemical Immunosensors for Multiple Cell Surface Biomarkers on Liver Cancer Stem Cells. (2017). Electroanalysis 29 (8), 1994-2000, 2017.

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https://scholar.google.com/citations?view_op=view_citation&hl=en&user=9ji_owIAA…

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Associate Editor

Frontiers in Sensors

https://www.frontiersin.org/journals/sensors/editors

Guest Editor in Biosensors

Biosensors is an International, peer-reviewed journal focusing on recent research in the science and technology of biosensors. Dr. Raja Chinnappan is serving as a Guest Editor of a special issue "Aptasensor for Biomarker Detection: From Design to Applications" https://www.mdpi.com/si/139699

Dr. Chinnappan is one of the Editorial members of Frontiers in Sensor's special issue " Microfluidics-based Sensors for One Health" Microfluidics-based Sensors for One Health | Frontiers Research Topic (frontiersin.org)

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MBS 502 - Methods in Molecular & Cellular Biology