Dr. Ahmed Yaqinuddin

Vice Dean for Graduate Studies & Research, Prof. of Anatomy & Cell Biology

Bio

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C.V
Education:
PhD (Anatomy)                   2008                       Aga Khan University, Karachi, Pakistan
MBBS                                    1996                       Baqai Medical college, University of Karachi, Pakistan
Professional Training/ Positions:



Assistant Professor


2009-present


Aga Khan University, Karachi, Pakistan.




Instructor (Anatomy)


2006-2008


Aga Khan University, Karachi, Pakistan.




Doctoral Fellow
 
Instructor (Anatomy)


2002-2008
 
2000-2002


Aga khan University, Karachi, Pakistan. Shifa College of Medicine, Islamabad,
Pakistan.




 
Instructor (Anatomy)


 
1998-2000


Islamabad Medical College, Islamabad, Pakistan.




 
Senior House Surgeon


 
1997-1998


Surgical Rotations in University and Cen
Hospital – Riyadh




 
Research Interests:


 


 



•      Role of epigenetic mechanisms in development and progression of cancers
•      Utility of epigenetic markers ( DNA methylation and miRNAs) to detect and prognosticate cancers
 Current projects:
•      Using microRNAs as a biomarker to diagnose and prognosticate breast cancer
•   Global methylation profiling in bladder cancer; An approach to discover novel diagnostic and prognostic biomarkers
•     A novel approach to non invasive prenatal diagnosis feotal Rhesus-D status by isolating cell free feotal DNA in maternal Plasma
Teaching:
•      Teaching Anatomy through lectures, tutorials, lab sessions to Undergraduate medical students, Islamabad Medical and Dental College, Islamabad 1998-2000.
•    Teaching Anatomy, through lectures, tutorials, lab sessions to Undergraduate medical students, Shifa College of Medicine, Islamabad, 2000-2002.
•      Teaching Anatomy, through lectures, tutorials, lab sessions to Undergraduate medical students Aga Khan University, Karachi 2002- to-date.
•      Working as Point Person Anatomy with responsibility to manage overall teaching related activities of Anatomy discipline in the Department of Biological and Biomedical Sciences, the Aga Khan University, Karachi 2008-todate.
•      Co-Chair Year I Curriculum Sub-Committee, Medical College, Aga Khan University, 2009-todate
•      Co-Chair Head &Neck and Special Senses Module, Medical College, Aga Khan University, 2008-to-date
•      Member, Year II Curriculum Sub-Committee, Medical College, Aga Khan University, 2008-to-date

Publications

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COVID-19 associated cardiac disease: Is there a role of neutrophil extracellular traps in pathogenesis?

Journal Article ,
Yaqinuddin, A. . (2021). COVID-19 associated cardiac disease: Is there a role of neutrophil extracellular traps in pathogenesis?. Molecular Science. (Original work published 2021)
Google scholar Link
http://www.aimspress.com/journal/Molecular

Implementation of structured team-based review enhances knowledge consolidation and academic performance of undergraduate medical students studying neuroscience

Journal Article ,
Implementation of structured team-based review enhances knowledge consolidation and academic performance of undergraduate medical students studying neuroscience. (2020). Advances in Physiology Education. (Original work published 2020)
Google scholar Link
https://doi.org/10.1152/advan.00162.2019

Innate immunity in COVID-19 patients mediated by NKG2A receptors, and potential treatment using Monalizumab, Cholroquine, and antiviral agents

Journal Article ,
Yaqinuddin, A. . (2020). Innate immunity in COVID-19 patients mediated by NKG2A receptors, and potential treatment using Monalizumab, Cholroquine, and antiviral agents. Medical Hypotheses. (Original work published 2020)
Google scholar Link
https://doi.org/10.1016/j.mehy.2020.109777

The central role of neutrophil extracellular traps in SARS-CoV-2-induced thrombogenesis and vasculitis.

Journal Article ,
Yaqinuddin, A. . (2020). The central role of neutrophil extracellular traps in SARS-CoV-2-induced thrombogenesis and vasculitis. African Journal of Respiratory Medicine, 2020, Vol 15, Issue 2, p24. (Original work published 2020)

Loop mediated isothermal amplification (LAMP) assays as a rapid diagnostic for COVID-19

Journal Article ,
Yaqinuddin, A. . (2020). Loop mediated isothermal amplification (LAMP) assays as a rapid diagnostic for COVID-19. Medical Hypotheses. (Original work published 2020)
Google scholar Link
https://doi.org/10.1016/j.mehy.2020.109786

Vertical integration of head, neck, and special senses module in undergraduate medical curriculum SA Arain, S Kumar, A Yaqinuddin, SA Meo

Journal Article ,
Vertical integration of head, neck, and special senses module in undergraduate medical curriculum SA Arain, S Kumar, A Yaqinuddin, SA Meo. (2020). Advances in Physiology Education. (Original work published 2020)
Google scholar Link
https://doi.org/10.1152/advan.00173.2019

COVID-19: Role of neutrophil extracellular traps in acute lung injury

Journal Article ,
Yaqinuddin, A. . (2020). COVID-19: Role of neutrophil extracellular traps in acute lung injury. Respiratory Investigation. (Original work published 2020)
Google scholar Link
https://doi.org/10.1016/j.resinv.2020.06.001

Novel therapeutic targets for SARS-CoV-2-induced acute lung injury: Targeting a potential IL-1β/neutrophil extracellular traps feedback loop

Journal Article ,
Novel therapeutic targets for SARS-CoV-2-induced acute lung injury: Targeting a potential IL-1β/neutrophil extracellular traps feedback loop. (2020). Medical Hypotheses. (Original work published 2020)
Google scholar Link
https://doi.org/10.1016/j.mehy.2020.109906

Applying integrated video assisted learning approaches for medical clerkship–potential adaptations in the post-COVID-19 era

Journal Article ,
Applying integrated video assisted learning approaches for medical clerkship–potential adaptations in the post-COVID-19 era. (2020). Journal of Medical Education and Curricular Development. (Original work published 2020)
Google scholar Link
https://doi.org/10.1177/2382120520963043

Cross-immunity between respiratory coronaviruses may limit COVID-19 fatalities

Journal Article ,
Yaqinuddin, A. . (2020). Cross-immunity between respiratory coronaviruses may limit COVID-19 fatalities. Medical Hypotheses. (Original work published 2020)
Google scholar Link
https://doi.org/10.1016/j.mehy.2020.110049

Comparative analysis of effectiveness between flipped classroom and lecture-based classroom in undergraduate medical education at Alfaisal University

Journal Article ,
Comparative analysis of effectiveness between flipped classroom and lecture-based classroom in undergraduate medical education at Alfaisal University. (2020). Cureus. (Original work published 2020)
Google scholar Link
https://doi.org/10.7759/cureus.11408

Medical education dilemma: how best to accommodate basic sciences in a curriculum for the 21st century medical students?

Journal Article ,
Medical education dilemma: how best to accommodate basic sciences in a curriculum for the 21st century medical students?. (2019). Canadian Journal of Physiology and Pharmacology. (Original work published 2019)
Google scholar Link
https://www.nrcresearchpress.com/doi/abs/10.1139/cjpp-2018-0428

Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population

Journal Article ,
Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population. (2019). Journal of Biochemical and Clinical Genetics. (Original work published 2019)
Google scholar Link
http://dx.doi.org/10.24911/JBCGenetics/183-1538333316

Highly sensitive multiplex detection of microRNA by competitive DNA strand displacement fluorescence assay

Journal Article ,
Highly sensitive multiplex detection of microRNA by competitive DNA strand displacement fluorescence assay. (2019). Talanta. (Original work published 2019)
Google scholar Link
https://doi.org/10.1016/j.talanta.2019.03.061

DNA Methylation of Multiple Genes involved in Bladder Cancer among Saudi Population

Journal Article ,
Yaqinuddin, A. . (2018). DNA Methylation of Multiple Genes involved in Bladder Cancer among Saudi Population. The FASEB Journal. (Original work published 2018)
Google scholar Link
https://doi.org/10.1096/fasebj.2018.32.1_supplement.787.4

MicroRNAs in Breast Cancer; Growing Understanding of their Role in Metastasis and Invasion

Journal Article ,
Yaqinuddin, A. . (2017). MicroRNAs in Breast Cancer; Growing Understanding of their Role in Metastasis and Invasion. The FASEB Journal. (Original work published 2017)
Google scholar Link
https://doi.org/10.1096/fasebj.31.1_supplement.721.8

The integrated clinical anatomy program at Alfaisal University: an innovative model of teaching clinically applied functional anatomy in a hybrid curriculum

Journal Article ,
Yaqinuddin, A. . (2016). The integrated clinical anatomy program at Alfaisal University: an innovative model of teaching clinically applied functional anatomy in a hybrid curriculum. Advances in Physiology Education.
Google scholar Link
https://doi.org/10.1152/advan.00153.2015

Determination of methylation status of RASSF1A, APC and ITH5 as diagnostic and prognostic biomarkers in tissue samples of breast cancer patients from Saudi population

Journal Article ,
Determination of methylation status of RASSF1A, APC and ITH5 as diagnostic and prognostic biomarkers in tissue samples of breast cancer patients from Saudi population. (2016). EUROPEAN JOURNAL OF CANCER. (Original work published 2016)

Assessment of first-year medical students’ perceptions of teaching and learning through team-based learning sessions

Journal Article ,
Yaqinuddin, A. . (2016). Assessment of first-year medical students’ perceptions of teaching and learning through team-based learning sessions. Advances in Physiology Education.
Google scholar Link
https://doi.org/10.1152/advan.00001.2016

Pharmacological effects of Ibuprofen on learning and memory, muscarinic receptors gene expression and APP isoforms level in pre-frontal cortex of AlCl3-induced toxicity mouse model

Journal Article ,
Pharmacological effects of Ibuprofen on learning and memory, muscarinic receptors gene expression and APP isoforms level in pre-frontal cortex of AlCl3-induced toxicity mouse model. (2015). International Journal of Neuroscience 125 (4), 277-287.

Cyclooxygenase I and II inhibitors distinctly enhance hippocampal-and cortex-dependent cognitive functions in mice

Journal Article ,
Cyclooxygenase I and II inhibitors distinctly enhance hippocampal-and cortex-dependent cognitive functions in mice. (2015). Molecular Medicine Reports 12 (5), 7649-7656.

Undergraduate Research: An Innovative Student-Centered Committee from the Kingdom of Saudi Arabia

Journal Article ,
Undergraduate Research: An Innovative Student-Centered Committee from the Kingdom of Saudi Arabia. (2014). Med Teach, 36.

Summer Pre-Med Program (SPP) for Matriculating Medical Students: A Student-Led Initiative

Journal Article ,
Summer Pre-Med Program (SPP) for Matriculating Medical Students: A Student-Led Initiative. (2014). Adv Physiol Educ, 38, 56-61.

Pharmacological effects of Ibuprofen on learning and memory, Muscarinic receptors genes expression and APP isoforms levels in Pre-frontal cortex of AlCl3-induced mice model

Journal Article ,
Pharmacological effects of Ibuprofen on learning and memory, Muscarinic receptors genes expression and APP isoforms levels in Pre-frontal cortex of AlCl3-induced mice model. (2014). International Journal of Neuroscience.

Health and Disease: Curriculum for 21st Century Medical Students

Book ,
Health and Disease: Curriculum for 21st Century Medical Students. (2014). New York: Nova publishers.

Gastrointestinal Mucosal Defense System

Book ,
Gastrointestinal Mucosal Defense System. (2014). Philadelphia, USA,: Morgan and Claypool Publishers.

Comparative study of therapeutic effects of Cyclooxygenase I and II inhibitors in AlCl3-induced mouse model of Alzheimer’s disease

Journal Article ,
Comparative study of therapeutic effects of Cyclooxygenase I and II inhibitors in AlCl3-induced mouse model of Alzheimer’s disease. (2014). Brain Reserach.

Cardiac Angiogenesis: Role of Cardiomyocytes and Macrophages and Possible Therapeutic Approaches

Journal Article ,
Cardiac Angiogenesis: Role of Cardiomyocytes and Macrophages and Possible Therapeutic Approaches. (2014). Current Angiogenesis.

What is an Objective Structured Practical Examination (OSPE) in Anatomy?

Journal Article ,
What is an Objective Structured Practical Examination (OSPE) in Anatomy?. (2013). Anatomical Sciences Education, 6, 125-33.

Problem based learning as an instructional method

Journal Article ,
Problem based learning as an instructional method. (2013). JCPSP, 23, 83-85.

Frequent hypermethylation of APC, RAR-Beta and RASSF1A in human term placentas

Journal Article ,
Frequent hypermethylation of APC, RAR-Beta and RASSF1A in human term placentas. (2013). Italian Journal of Anatomy and Embryology, 118, 211-216.

Frequent DNA hypermethylation at RASSF1A and APC gene loci in prostate cancer patients of Pakistani origin

Journal Article ,
Frequent DNA hypermethylation at RASSF1A and APC gene loci in prostate cancer patients of Pakistani origin. (2013). ISRN Urol.

“PBL correlates with content acquisition assessment: a study at hybrid PBL program at Alfaisal University

Journal Article ,
“PBL correlates with content acquisition assessment: a study at hybrid PBL program at Alfaisal University. (2012). Med Teacher, 34, 83.

An innovative approach to inculcate analytical and non-analytical clinical reasoning among medical students

Journal Article ,
An innovative approach to inculcate analytical and non-analytical clinical reasoning among medical students. (2012). Med Tech, 34, 511-12.

Utility of DNA methylation markers for diagnosing cancer

Journal Article ,
Utility of DNA methylation markers for diagnosing cancer. (2011). Utility of DNA Methylation Markers for Diagnosing Cancer.

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