Dr. Pallab Kumar Ganguly

Professor of Anatomy (HOD)

Bio

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Education:

FACA, 1989
American College of Angiology, USA

Post Doctoral Training, 1982-1987
University of Manitoba, Canada

MD, 1982
All-India Institute of Medical Sciences, India

MBBS, 1978
North Bengal University, India

Awards and Honors:

Scholar-Heart and Stroke Foundation, Canada
Merit Award-University of Manitoba, Canada
Rh Award-University of Manitoba, Canada
Young Investigator Award-Canadian Cardiovascular Society
Young Investigator Award-American College of Angiology
Visiting Professor-Harvard Medical School
Gold Medal-International Society for Heart Research

Asian Leadership Award-Best Anatomy Professor, Dubai,  September 24, 2013
Most popular professor-Alfaisal University, 2013
Best Professor (Research), College of medicine, Alfaisal University, 2014

Goyal oration award, International Academy of Cardiovascular Sciences, Indian section, Bengaluru, 2019



Appointments:

Assistant Professor University of Manitoba, Canada 1988
Associate Professor University of Manitoba, Canada 1993
Professor and Chairman Arabian Gulf University, Bahrain 2000
Scientific Consultant St. Boniface Hospital Res. Centre Canada  1989-present
Professor Alfaisal University 2008-present
Chairman, Department of Anatomy 2008-present


Research Interests:

 Cardiovascular Sciences: Increased plasma homocysteine is associated with stroke but its direct effects on the brain during a stroke are unknown. Since Excitatory amino acids are important in inducing brain damage, we examined the effects of homocysteine on the release of various amino acids in the striatum of experimental animals. Homocysteine-induced neurological damage in spontaneously hypertensive stroke prone rats was associated with a hypersecretion of excitatory amino acids. Future goal is to prove the hypothesis if subjects with hyperhomocysteinemia may be at risk for augmented brain damage from an ischemic infarct due to a selective activation of neuronal excitatory amino acids.
Medical Education: The research is directed towards curriculum development, innovative teaching methods and planning an effective assessment system in a new medical school.


Current projects:

Cardiac function in hyperhomocysteinemia: In order to understand how hyperhomocysteinemia can affect hypothalamic injury, autonomic and cardiac dysfunction, interstitial fluid will be collected from brain after homocysteine challenge and the perfusate will be evaluated for catecholamines and amino acids. The data will be correlated with cardiac function (the project has been submitted to KACST).
Medical Education: Assessment system at Alfaisal University: perception of medical students

 
Teaching:
University of Manitoba (Winnipeg, Canada) (1986-1997)-Undergraduate Program

Gross anatomy, Histology, Cardiovascular Sciences

University of Manitoba (Winnipeg, Canada) (1988-1997)-Graduate Program

Supervised PhD and Master students

Arabian Gulf University, Bahrain (1998-2005)

Gross anatomy, Embryology, Histology, Neuroscience

St. Matthews University, Grand Cayman

Gross anatomy, Embryology, Histology

Alfaisal University, Riyadh, KSA (since September 2008)

Human biology and structure (gross anatomy and histology)
Human growths and development (embryology)
Neuroscience

 

 

CVPKGanguly1.pdf (290.1 KB)

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Publications

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Captopril treatment improves the sarcoplasmic reticular Ca2+ transport in heart failure due to myocardial infarction

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Captopril treatment improves the sarcoplasmic reticular Ca2+ transport in heart failure due to myocardial infarction. (1999). Journal of Molecular and Cellular Cardiology 31 (9), 1663-1672, 1999.

Extracorporeal liver perfusion system for successful hepatic support pending liver regeneration or liver transplantation: a preclinical controlled trial

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Extracorporeal liver perfusion system for successful hepatic support pending liver regeneration or liver transplantation: a preclinical controlled trial. (1999). Transplantation 67 (12), 1576-1583, 1999.

Stress, sympathetic activity and heart disease: Is there any common mediator?

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Stress, sympathetic activity and heart disease: Is there any common mediator?. (1998). SAUDI MEDICAL JOURNAL 19 (6), 812-812, 1998.

Stress, sympathetic activity and heart disease: Is there any common mediator? Reply from author

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Stress, sympathetic activity and heart disease: Is there any common mediator? Reply from author. (1998). SAUDI MEDICAL JOURNAL 19 (6), 812-812, 1998.

Index to Volume 188

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Index to Volume 188. (1998). Molecular and Cellular Biochemistry 188, 235-237, 1998.

Hypertension, calcium channel and pyridoxine (vitamin B6)

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Hypertension, calcium channel and pyridoxine (vitamin B6). (1998). Molecular and Cellular Effects of Nutrition on Disease Processes, 137-148, 1998.

Renal Ca 2+ pump activity in JCR: LA-Corpulent Rats

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Renal Ca 2+ pump activity in JCR: LA-Corpulent Rats. (1997). INTERNATIONAL JOURNAL OF DIABETES 5, 120-125, 1997.

Differential changes in sympathetic activity in left and right ventricles in congestive heart failure after myocardial infarction

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Differential changes in sympathetic activity in left and right ventricles in congestive heart failure after myocardial infarction. (1997). American Heart Journal 133 (3), 340-345, 1997.

Neuropeptide Y modulation of sympathetic activity in myocardial infarction

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Neuropeptide Y modulation of sympathetic activity in myocardial infarction. (1996). Journal of the American College of Cardiology 27 (7), 1796-1803, 1996.

Neurally mediated cardiac effects of forskolin in conscious dogs

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Neurally mediated cardiac effects of forskolin in conscious dogs. (1996). American Journal of Physiology-Heart and Circulatory Physiology 271 (4 …, 1996.

Neuropeptide Y prevents agonist-stimulated increases in contractility

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Neuropeptide Y prevents agonist-stimulated increases in contractility. (1995). Hypertension 26 (3), 480-484, 1995.

Up-regulation of cholecystokinin receptors in the nucleus accumbens of the young prehypertensive spontaneously hypertensive rat

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Up-regulation of cholecystokinin receptors in the nucleus accumbens of the young prehypertensive spontaneously hypertensive rat. (1995). Neuroscience Letters 191 (3), 197-199, 1995.

Topographical organization in the nucleus accumbens of afferents from the basolateral amygdala and efferents to the lateral hypothalamus

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Topographical organization in the nucleus accumbens of afferents from the basolateral amygdala and efferents to the lateral hypothalamus. (1995). Neuroscience 67 (3), 625-630, 1995.

Cholecystokinin-induced release of dopamine in the nucleus accumbens of the spontaneously hypertensive rat

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Cholecystokinin-induced release of dopamine in the nucleus accumbens of the spontaneously hypertensive rat. (1995). Brain Research 689 (2), 245-253, 1995.

Renal dopamine receptors are involved in the development of cardiac hypertrophy

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Renal dopamine receptors are involved in the development of cardiac hypertrophy. (1995). Molecular and Cellular Biochemistry 144 (1), 81-84, 1995.

Renal D1 receptors, and not D2, are upregulated after aortic constriction and may be involved in cardiac hypertrophy

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Renal D1 receptors, and not D2, are upregulated after aortic constriction and may be involved in cardiac hypertrophy. (1994). Journal of Autonomic Pharmacology 14 (4), 307-316, 1994.

BENEXTRAMINE (BNX) REVERSES MODULATORY EFFECT OF NEUROPEPTIDE-Y (NPY) ON NOREPINEPHRINE (NE) IN HYPERTENSION

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BENEXTRAMINE (BNX) REVERSES MODULATORY EFFECT OF NEUROPEPTIDE-Y (NPY) ON NOREPINEPHRINE (NE) IN HYPERTENSION. (1994). FASEB JOURNAL 8 (5), A846-A846, 1994.

Transport Systems in Kidney Basolateral Membrane: Pathophysiologic Implications

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Transport Systems in Kidney Basolateral Membrane: Pathophysiologic Implications. (1994). Membrane Physiopathology, 249-270, 1994.

Altered neuropeptide Y effects on noradrenaline levels in the paraventricular nucleus of rats following aortic constriction.

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Altered neuropeptide Y effects on noradrenaline levels in the paraventricular nucleus of rats following aortic constriction. (1994). The Canadian Journal of Cardiology 10 (4), 471-476, 1994.

Adrenoreceptor-mediated effect of neuropeptide Y decreases cardiac inotropic responses

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Adrenoreceptor-mediated effect of neuropeptide Y decreases cardiac inotropic responses. (1994). Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1222 (3), 457-463, 1994.

Renal handling of Ca2+ in diabetes

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Renal handling of Ca2+ in diabetes. (1994). Molecular and Cellular Biochemistry 135 (1), 109-112, 1994.

Renal Ca2++ Mg2+ ATPase in congestive heart failure due to diabetes

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Renal Ca2++ Mg2+ ATPase in congestive heart failure due to diabetes. (1993). Angiology 44 (10), 769-775, 1993.

Observations on atrial natriuretic peptide, sympathetic activity and renal Ca2+ pump in diabetic and hypertensive rats

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Observations on atrial natriuretic peptide, sympathetic activity and renal Ca2+ pump in diabetic and hypertensive rats. (1993). Clinical Autonomic Research 3 (2), 137-143, 1993.

Effect of statil on kidney structure, function and polyol accumulation in diabetes mellitus

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Effect of statil on kidney structure, function and polyol accumulation in diabetes mellitus. (1993). Molecular and Cellular Biochemistry 125 (1), 27-33, 1993.

Up-regulation of dopamine receptors in the brain of the spontaneously hypertensive rat: an autoradiographic analysis

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Up-regulation of dopamine receptors in the brain of the spontaneously hypertensive rat: an autoradiographic analysis. (1993). Neuroscience 52 (1), 135-141, 1993.

Cholecystokinin receptor density in the striatum of the spontaneously hypertensive rat

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Cholecystokinin receptor density in the striatum of the spontaneously hypertensive rat. (1993). Brain Research 604 (1-2), 338-341, 1993.

Norepinephrine levels in paraventricular nucleus of spontaneously hypertensive rats: role of neuropeptide Y

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Norepinephrine levels in paraventricular nucleus of spontaneously hypertensive rats: role of neuropeptide Y. (1993). American Journal of Physiology-Heart and Circulatory Physiology 265 (3 …, 1993.

Atrial natriuretic peptide: pathophysiological considerations.

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Atrial natriuretic peptide: pathophysiological considerations. (1992). Indian Journal of Physiology and Pharmacology 36 (1), 3-14, 1992.

Altered renal dopamine receptors during development of cardiac hypertrophy

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Altered renal dopamine receptors during development of cardiac hypertrophy. (1992). American Journal of Physiology-Endocrinology and Metabolism 262 (5), E569-E573, 1992.

Modification of cardiac adrenergic receptors by oxygen free radicals

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Modification of cardiac adrenergic receptors by oxygen free radicals. (1991). American Journal of Physiology-Heart and Circulatory Physiology 260 (3 …, 1991.

Modulation of sympathetic activity by brain neuropeptide Y in cardiac hypertrophy

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Modulation of sympathetic activity by brain neuropeptide Y in cardiac hypertrophy. (1991). American Heart Journal 122 (4), 1028-1034, 1991.

(Ca2++ Mg2+) ATPase activity in kidney basolateral membrane in diabetes: role of atrial natriuretic peptide

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(Ca2++ Mg2+) ATPase activity in kidney basolateral membrane in diabetes: role of atrial natriuretic peptide. (1991). Molecular and Cellular Biochemistry 105 (1), 15-20, 1991.

Myocardial adrenergic changes at two stages of heart failure due to adriamycin treatment in rats

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Myocardial adrenergic changes at two stages of heart failure due to adriamycin treatment in rats. (1991). American Journal of Physiology-Heart and Circulatory Physiology 260 (3 …, 1991.

Noradrenaline turnover and metabolism in myocardium following aortic constriction in rats

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Noradrenaline turnover and metabolism in myocardium following aortic constriction in rats. (1991). Cardiovascular Research 25 (7), 579-585, 1991.

Role of atrial natriuretic peptide in congestive heart failure due to chronic diabetes.

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Role of atrial natriuretic peptide in congestive heart failure due to chronic diabetes. (1991). The Canadian Journal of Cardiology 7 (6), 275-280, 1991.

Congestive heart failure in diabetes with hypertension may be due to uncoupling of the atrial natriuretic peptide receptor-effector system in the kidney basolateral membrane

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Congestive heart failure in diabetes with hypertension may be due to uncoupling of the atrial natriuretic peptide receptor-effector system in the kidney basolateral membrane. (1991). American Heart Journal 122 (1), 164-170, 1991.

Antioxidant therapy in congestive heart failure: is there any advantage?

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Antioxidant therapy in congestive heart failure: is there any advantage?. (1991). Journal of Internal Medicine 229 (3), 205-208, 1991.

Catecholamines and heart disease

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Catecholamines and heart disease. (1991). CRC Press, 1991.

CATECHOLAMINE LEVELS IN THE BRAIN FOLLOWING AORTIC CONSTRICTION IN RATS-EFFECT OF NEUROPEPTIDE-Y

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CATECHOLAMINE LEVELS IN THE BRAIN FOLLOWING AORTIC CONSTRICTION IN RATS-EFFECT OF NEUROPEPTIDE-Y. (1991). HYPERTENSION 18 (3), 376-376, 1991.

Impaired inotropic responses to adrenergic stimulation following aortic constriction: role of oxidation product of catecholamines

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Impaired inotropic responses to adrenergic stimulation following aortic constriction: role of oxidation product of catecholamines. (1991). Angiology 42 (2), 133-139, 1991.

Central control of cardiac hypertrophy

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Central control of cardiac hypertrophy. (1991). Catecholamines and Heart Disease. PK Ganguly (ed.) Boca Raton, FL CRC, 163-176, 1991.

EXTRACELLULAR NOREPINEPHRINE CONCENTRATIONS IN THE BRAIN FOLLOWING ABDOMINAL AORTIC CONSTRICTION IN THE RAT-A MICRODIALYSIS STUDY

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EXTRACELLULAR NOREPINEPHRINE CONCENTRATIONS IN THE BRAIN FOLLOWING ABDOMINAL AORTIC CONSTRICTION IN THE RAT-A MICRODIALYSIS STUDY. (1991). FASEB JOURNAL 5 (5), A1411-A1411, 1991.

Cardiac sympathetic system: basic aspects

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Cardiac sympathetic system: basic aspects. (1991). Catecholamines and Heart Disease, 1-13, 1991.

Increased sarcolemmal Ca2+ transport activity in skeletal muscle of diabetic rats

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Increased sarcolemmal Ca2+ transport activity in skeletal muscle of diabetic rats. (1991). American Journal of Physiology-Endocrinology And Metabolism 260 (4), E626-E632, 1991.

Stress catecholamines, and heart disease

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Stress catecholamines, and heart disease. (1991). Catecholamines and Heart Disease, 231, 1991.

Modulation of cardiac β-adrenergic receptors by dopamine β-hydroxylase

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Modulation of cardiac β-adrenergic receptors by dopamine β-hydroxylase. (1990). Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1055 (2), 186-188, 1990.

Evidence against the involvement of nonenzymatic glycosylation in diabetic cardiomyopathy

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Evidence against the involvement of nonenzymatic glycosylation in diabetic cardiomyopathy. (1990). Metabolism 39 (7), 769-773, 1990.

Alterations in phospholipid N-methylation of cardiac subcellular membranes due to experimentally induced diabetes in rats.

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Alterations in phospholipid N-methylation of cardiac subcellular membranes due to experimentally induced diabetes in rats. (1990). The Journal of Clinical Investigation 86 (3), 777-784, 1990.

Role of atrial natriuretic peptide in the modulation of kidney (Ca2++ Mg2+)-ATPase in chronic diabetes

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Role of atrial natriuretic peptide in the modulation of kidney (Ca2++ Mg2+)-ATPase in chronic diabetes. (1990). Journal of Molecular and Cellular Cardiology 22, S18, 1990.

Lack of response of (Ca2++ Mg2+) ATPase to atrial natriuretic peptide in basolateral membranes from kidney cortex of chronic diabetic rats

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Lack of response of (Ca2++ Mg2+) ATPase to atrial natriuretic peptide in basolateral membranes from kidney cortex of chronic diabetic rats. (1990). Biochemical and Biophysical Research Communications 169 (2), 537-544, 1990.

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