Dr. Pallab Kumar Ganguly

Professor of Anatomy (HOD)

Bio

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Education:

FACA, 1989
American College of Angiology, USA

Post Doctoral Training, 1982-1987
University of Manitoba, Canada

MD, 1982
All-India Institute of Medical Sciences, India

MBBS, 1978
North Bengal University, India

Awards and Honors:

Scholar-Heart and Stroke Foundation, Canada
Merit Award-University of Manitoba, Canada
Rh Award-University of Manitoba, Canada
Young Investigator Award-Canadian Cardiovascular Society
Young Investigator Award-American College of Angiology
Visiting Professor-Harvard Medical School
Gold Medal-International Society for Heart Research

Asian Leadership Award-Best Anatomy Professor, Dubai,  September 24, 2013
Most popular professor-Alfaisal University, 2013
Best Professor (Research), College of medicine, Alfaisal University, 2014

Goyal oration award, International Academy of Cardiovascular Sciences, Indian section, Bengaluru, 2019



Appointments:

Assistant Professor University of Manitoba, Canada 1988
Associate Professor University of Manitoba, Canada 1993
Professor and Chairman Arabian Gulf University, Bahrain 2000
Scientific Consultant St. Boniface Hospital Res. Centre Canada  1989-present
Professor Alfaisal University 2008-present
Chairman, Department of Anatomy 2008-present


Research Interests:

 Cardiovascular Sciences: Increased plasma homocysteine is associated with stroke but its direct effects on the brain during a stroke are unknown. Since Excitatory amino acids are important in inducing brain damage, we examined the effects of homocysteine on the release of various amino acids in the striatum of experimental animals. Homocysteine-induced neurological damage in spontaneously hypertensive stroke prone rats was associated with a hypersecretion of excitatory amino acids. Future goal is to prove the hypothesis if subjects with hyperhomocysteinemia may be at risk for augmented brain damage from an ischemic infarct due to a selective activation of neuronal excitatory amino acids.
Medical Education: The research is directed towards curriculum development, innovative teaching methods and planning an effective assessment system in a new medical school.


Current projects:

Cardiac function in hyperhomocysteinemia: In order to understand how hyperhomocysteinemia can affect hypothalamic injury, autonomic and cardiac dysfunction, interstitial fluid will be collected from brain after homocysteine challenge and the perfusate will be evaluated for catecholamines and amino acids. The data will be correlated with cardiac function (the project has been submitted to KACST).
Medical Education: Assessment system at Alfaisal University: perception of medical students

 
Teaching:
University of Manitoba (Winnipeg, Canada) (1986-1997)-Undergraduate Program

Gross anatomy, Histology, Cardiovascular Sciences

University of Manitoba (Winnipeg, Canada) (1988-1997)-Graduate Program

Supervised PhD and Master students

Arabian Gulf University, Bahrain (1998-2005)

Gross anatomy, Embryology, Histology, Neuroscience

St. Matthews University, Grand Cayman

Gross anatomy, Embryology, Histology

Alfaisal University, Riyadh, KSA (since September 2008)

Human biology and structure (gross anatomy and histology)
Human growths and development (embryology)
Neuroscience

 

 

CVPKGanguly1.pdf (290.1 KB)

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Publications

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Catecholamines and cardiovascular disorders: pathophysiologic considerations.

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Catecholamines and cardiovascular disorders: pathophysiologic considerations. (1989). American Heart Journal 118 (4), 868-872, 1989.

Alterations of phosphatidylethanolamine N-methylation in rat heart by quinidine.

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Alterations of phosphatidylethanolamine N-methylation in rat heart by quinidine. (1989). Journal of Cardiovascular Pharmacology 14 (5), 763-769, 1989.

IN DIABETIC CARDIOMYOPATHY

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IN DIABETIC CARDIOMYOPATHY. (1989). Pathophysiology and Pharmacology of Heart Disease: Proceedings of the …, 1989.

Measurement of adrenolutin as an oxidation product of catecholamines in plasma

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Measurement of adrenolutin as an oxidation product of catecholamines in plasma. (1989). Molecular and Cellular Biochemistry 87 (1), 85-92, 1989.

Catecholamine cardiotoxicity in pheochromocytoma.

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Catecholamine cardiotoxicity in pheochromocytoma. (1989). American Heart Journal 117 (6), 1399-1400, 1989.

Altered sympathetic system and adrenoceptors during the development of cardiac hypertrophy

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Altered sympathetic system and adrenoceptors during the development of cardiac hypertrophy. (1989). American Heart Journal 118 (3), 520-525, 1989.

Abnormalities of adrenergic mechanisms in diabetic cardiomyopathy

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Abnormalities of adrenergic mechanisms in diabetic cardiomyopathy. (1989). Pathophysiology and Pharmacology of Heart Disease, 197-203, 1989.

Involvement of the sympathetic nervous system in the development of cardiac hypertrophy: a fresh look at an old problem

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Involvement of the sympathetic nervous system in the development of cardiac hypertrophy: a fresh look at an old problem. (1989). Journal of Autonomic Pharmacology 9 (5), 367-378, 1989.

Beneficial effects of verapamil in diabetic cardiomyopathy

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Beneficial effects of verapamil in diabetic cardiomyopathy. (1988). Diabetes 37 (7), 936-942, 1988.

Increased SR phospholipid N-methylation in skeletal muscle of diabetic rats

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Increased SR phospholipid N-methylation in skeletal muscle of diabetic rats. (1988). American Journal of Physiology-Endocrinology and Metabolism 255 (3), E347-E352, 1988.

Methionine-induced positive inotropic effect in rat heart: possible role of phospholipid N-methylation.

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Methionine-induced positive inotropic effect in rat heart: possible role of phospholipid N-methylation. (1988). Circulation Research 62 (1), 51-55, 1988.

Altered contractile proteins in skeletal muscle of diabetic rats

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Altered contractile proteins in skeletal muscle of diabetic rats. (1987). American Journal of Physiology-Endocrinology And Metabolism 253 (4), E395-E400, 1987.

Diabetic cardiomyopathy: membrane dysfunction and therapeutic strategies

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Diabetic cardiomyopathy: membrane dysfunction and therapeutic strategies. (1987). Journal of Applied Cardiology 2 (4), 323-338, 1987.

Decreased Ca2+-binding and Ca2+-ATPase activities in heart sarcolemma upon phospholipid methylation

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Decreased Ca2+-binding and Ca2+-ATPase activities in heart sarcolemma upon phospholipid methylation. (1987). Molecular and Cellular Biochemistry 78 (1), 65-71, 1987.

Experimental Cardiology Section, Department of Physiology, and Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Manitoba

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Experimental Cardiology Section, Department of Physiology, and Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Manitoba. (1987). Pathophysiology of Heart Disease: Proceedings of the Symposium Held at the …, 1987.

Methionine-induced positive inotropic effect in rat heart: Possible role of phospho-lipid N-methylation

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Methionine-induced positive inotropic effect in rat heart: Possible role of phospho-lipid N-methylation. (1987). Journal of Molecular and Cellular Cardiology 19, S58, 1987.

Ca2+ blocker therapy and cardiac function in diabetes

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Ca2+ blocker therapy and cardiac function in diabetes. (1987). Journal of Molecular and Cellular Cardiology 19, S63, 1987.

Catecholamine-induced cardiomyopathy: alterations in Ca transport systems

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Catecholamine-induced cardiomyopathy: alterations in Ca transport systems. (1987). Pathogenesis of Myocarditis and Cardiomyopathy, 135-147, 1987.

Involvement of Catecholamines in the development of diabetic Cardiomyopathy

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Involvement of Catecholamines in the development of diabetic Cardiomyopathy. (1987). Pathophysiology of Heart Disease, 237-248, 1987.

Norepinephrine storage, distribution, and release in diabetic cardiomyopathy

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Norepinephrine storage, distribution, and release in diabetic cardiomyopathy. (1987). American Journal of Physiology-Endocrinology And Metabolism 252 (6), E734-E739, 1987.

Inhibition of Na+–Ca2+ exchange in heart sarcolemmal vesicles by phosphatidylethanolamine N‐methylation

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Inhibition of Na+–Ca2+ exchange in heart sarcolemmal vesicles by phosphatidylethanolamine N‐methylation. (1987). European Journal of Biochemistry 166 (3), 597-603, 1987.

Reversibility of ultrastructural, contractile function and Ca2+ transport changes in guinea pig hearts after global ischemia

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Reversibility of ultrastructural, contractile function and Ca2+ transport changes in guinea pig hearts after global ischemia. (1986). Canadian Journal of Physiology and Pharmacology 64 (11), 1368-1375, 1986.

Calcium pump activity of sarcoplasmic reticulum in diabetic rat skeletal muscle

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Calcium pump activity of sarcoplasmic reticulum in diabetic rat skeletal muscle. (1986). American Journal of Physiology-Endocrinology And Metabolism 251 (5), E515-E523, 1986.

Quinidine-induced changes in cardiac sarcolemmal phospholipid N-methylation

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Quinidine-induced changes in cardiac sarcolemmal phospholipid N-methylation. (1986). Journal of Molecular and Cellular Cardiology 18, 110, 1986.

Altered norepinephrine turnover and metabolism in diabetic cardiomyopathy.

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Altered norepinephrine turnover and metabolism in diabetic cardiomyopathy. (1986). Circulation Research 59 (6), 684-693, 1986.

Muscle mechanics and Ca2+ transport in atrophic heart transplants in rat

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Muscle mechanics and Ca2+ transport in atrophic heart transplants in rat. (1986). American Journal of Physiology-Heart and Circulatory Physiology 251 (5 …, 1986.

INFLUENCE OF PHOSPHATIDYLETHANOLAMINE N-METHYLATION ON HEART SARCOLEMMAL CA-2+ TRANSPORT-SYSTEMS

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INFLUENCE OF PHOSPHATIDYLETHANOLAMINE N-METHYLATION ON HEART SARCOLEMMAL CA-2+ TRANSPORT-SYSTEMS. (1986). FEDERATION PROCEEDINGS 45 (3), 189-189, 1986.

Increased norepinephrine metabolism in diabetic cardiomyopathy

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Increased norepinephrine metabolism in diabetic cardiomyopathy. (1986). Journal of Molecular and Cellular Cardiology 18, 29, 1986.

Activation of Ca2+-stimulated ATPase by phospholipid N-methylation in cardiac sarcoplasmic reticulum

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Activation of Ca2+-stimulated ATPase by phospholipid N-methylation in cardiac sarcoplasmic reticulum. (1985). Biochemical and Biophysical Research Communications 130 (1), 472-478, 1985.

Norepinephrine turnover in streptozotocin-induced diabetic cardiomyopathy

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Norepinephrine turnover in streptozotocin-induced diabetic cardiomyopathy. (1985). JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 17 (12), R23-R23, 1985.

INHIBITION OF NA+-CA2+ EXCHANGE IN CARDIAC SARCOLEMMA BY PHOSPHOLIPID N-METHYLATION

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INHIBITION OF NA+-CA2+ EXCHANGE IN CARDIAC SARCOLEMMA BY PHOSPHOLIPID N-METHYLATION. (1985). JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 17 (12), R40-R40, 1985.

Subcellular localization of phosphatidylethanolamine N-methylation activity in rat heart

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Subcellular localization of phosphatidylethanolamine N-methylation activity in rat heart. (1985). Journal of Molecular and Cellular Cardiology 17 (12), 1151-1159, 1985.

Adaptive changes in subcellular calcium transport during catecholamine-induced cardiomyopathy

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Adaptive changes in subcellular calcium transport during catecholamine-induced cardiomyopathy. (1985). Journal of Molecular and Cellular Cardiology 17 (4), 411-420, 1985.

Behaviour of cardiac microsomal Ca2+ pump under conditions that may simulate pathological situations

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Behaviour of cardiac microsomal Ca2+ pump under conditions that may simulate pathological situations. (1985). Gen. Physiol. Biophys 4, 15-27, 1985.

Evidence for three catalytic sites in heart sarcolemmal phospholipid N-methylation.

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Evidence for three catalytic sites in heart sarcolemmal phospholipid N-methylation. (1985). Advances in Myocardiology 6, 157-164, 1985.

Modification of the function of cardiac subcellular organelles by insulin.

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Modification of the function of cardiac subcellular organelles by insulin. (1985). Advances in Myocardiology 6, 113-125, 1985.

Sarcolemmal phosphatidylethanolamine N-methylation in diabetic cardiomyopathy.

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Sarcolemmal phosphatidylethanolamine N-methylation in diabetic cardiomyopathy. (1984). Circulation Research 55 (4), 504-512, 1984.

Characterization of heart sarcolemmal phospholipid methylation

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Characterization of heart sarcolemmal phospholipid methylation. (1984). Biochimica Et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 792 (3), 245-253, 1984.

Alterations in the heart sarcolemmal Ca2+ transport activity by some β-adrenergic antagonists

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Alterations in the heart sarcolemmal Ca2+ transport activity by some β-adrenergic antagonists. (1984). Basic Research in Cardiology 79 (6), 620-626, 1984.

Altered sarcolemal phosphatidylethanolamine N-methylation during diabetic cardiomyopathy

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Altered sarcolemal phosphatidylethanolamine N-methylation during diabetic cardiomyopathy. (1984). Journal of Molecular and Cellular Cardiology 16, 17, 1984.

Defective sarcoplasmic reticular calcium transport in diabetic cardiomyopathy

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Defective sarcoplasmic reticular calcium transport in diabetic cardiomyopathy. (1983). American Journal of Physiology-Endocrinology And Metabolism 244 (6), E528-E535, 1983.

MONTHLY BIBLIOGRAPHY ON CELL CALCIUM PREPARED BY THE UNIVERSITY OF SHEFFIELD BIOMEDICAL INFORMATION SERVICE

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MONTHLY BIBLIOGRAPHY ON CELL CALCIUM PREPARED BY THE UNIVERSITY OF SHEFFIELD BIOMEDICAL INFORMATION SERVICE. (1983). J MUSCLE RES CELL MOTIL 4 (3), 1983.

Stimulation of calcium pump activity in heart sarcolemma by timolol

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Stimulation of calcium pump activity in heart sarcolemma by timolol. (1983). Canadian Journal of Physiology and Pharmacology 61 (3), 240-244, 1983.

Characterization of Ca2+ release from the cardiac sarcoplasmic reticulum

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Characterization of Ca2+ release from the cardiac sarcoplasmic reticulum. (1983). Gen Physiol Biophys 2, 339-351, 1983.

Alterations in isoproterenol-induced cardiac metabolic changes by a calcium antagonist, nifedipine

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Alterations in isoproterenol-induced cardiac metabolic changes by a calcium antagonist, nifedipine. (1982).

Nifedipine--a new calcium antagonist in experimental myocardial necrosis.

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Nifedipine--a new calcium antagonist in experimental myocardial necrosis. (1981). The Indian Journal of Medical Research 73, 617-624, 1981.

BIOCHEMICAL BASIS To BLOCK ISCHAEMIA DEVELOPING INTO MYOCARDIAL INFARCTION: A SHORT REVIEW.

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BIOCHEMICAL BASIS To BLOCK ISCHAEMIA DEVELOPING INTO MYOCARDIAL INFARCTION: A SHORT REVIEW. (1981). Journal of the Indian Institute of Science 63 (4), 53, 1981.

ALTERED LACTATE-DEHYDROGENASE ISOZYMES IN EXPERIMENTAL MYOCARDIAL ISCHEMIA

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ALTERED LACTATE-DEHYDROGENASE ISOZYMES IN EXPERIMENTAL MYOCARDIAL ISCHEMIA. (1981). INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 18 (4), 54-54, 1981.

Subcellular Organelles by Insulin

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Subcellular Organelles by Insulin. (1980). Advances in Myocardiology 6, 113, 1980.

Effect of oxyfedrine on myocardial glycolytic flux during ischaemia in rats.

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Effect of oxyfedrine on myocardial glycolytic flux during ischaemia in rats. (1980). Indian J Exp Biol, 1980.

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