Prof. Sabri Kemahli

Professor of Pediatrics

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Sabri KEMAHLI CV

CURRICULUM VITAE

DR.SABRİ KEMAHLI

 

PALCE AND DATE OF BIRTH :       ANKARA, 11.7.1954

FOREIGN LANGUAGES :   ENGLISH, GERMAN

CURRENT POSITION : 

  • Professor of Pediatrics, College of Medicine,  Alfaisal University, Saudi Arabia

CONTACT :

                                     Mobile  :   +90-532 264 55 02, 

                                                              +966-535 238 077

                                     Home  :      +90-312- 266 33 22

                                     E-mail: kemahlisabri@gmail.com; skemahli@alfaisal.edu

 EDUCATION AND TRAINING :                                                      

·         Resident at the Pediatric Hematology Division of Department of Pediatrics, Faculty of Medicine, Ankara University (1988-1989).

·         Resident in the Department of Pediatrics, Faculty of Medicine, Ankara University (1979-1984). 

·         Graduated from the Faculty of Medicine, Ankara University in 1978 as M.D.

 

DIPLOMAS AND DEGREES :

Professor of Pediatrics 1997 (Faculty of Medicine, Ankara University)

Pediatric Hematologist- 1991 (Faculty of Medicine, Ankara University)

Associate Professor of Pediatrics- 1989 (Faculty of Medicine, Ankara University)

Pediatrician- 1984 (Faculty of Medicine, Ankara University)

ECFMG-1980

Doctor of Medicine- 1978 (Faculty of Medicine, Ankara University)

 ACADEMIC APPOINTMENTS:

 

2011- ….. :Professor of Pediatrics (Ped. Hematology), Alfaisal University College of Medicine

2015-..:       Professor of Pediatrics (Ped. Hematology), Yeditepe University Faculty of Medicine, Istanbul, Turkey

2009-2011: Professor of Pediatrics, Al Kharj University College of Medicine

1997-2011 :  Professor of Pediatrics, Faculty of Medicine, Ankara University

2009- 2011: Professor of Pediatrics and Pediatric Hematology, College of Medicine, Al-Kharj University, Saudi Arabia

1996-2000 and 2005-2008:  Vice Dean (for Education and Academic Affairs), Faculty of Medicine, Ankara University

2000: ECFMG-IFME Fellow in Medical Education at University of Texas Medical Branch at Galveston, TX,USA (January-September 2000)

1997 – 2009: Director, Serpil Akdağ Blood Centre, Ankara University

1999 -2009:   Faculty member, Department of Medical Education and Informatics, Faculty of Medicine, Ankara University

1989-1997                  : Associate Professor of Pediatrics , Faculty of Medicine, Ankara University

1990:   Visiting scientist at the Haemophilia Centre and Haemostasis Unit, Royal Free Hospital, London, U.K.

1988  – 1989     : Resident at the Pediatric Hematology Division of Department of Pediatrics, Faculty of Medicine, Ankara University (1988-1989).

1985 – 1988  : Pediatrician at Atatürk Children's Home (Orphanage) of  the Social Services and Child Protection Agency (1985-1988).

1984    1985     : Military service at the Department of Pediatrics, Gülhane Military Medical Academy

1979    1984    : Resident in the Department of Pediatrics, Faculty of Medicine, Ankara University

 

 

 

 

MAIN FIELDS OF INTEREST AND EXPERIENCE: Medical Education, Hemostasis and thrombosis, thalassemia and hemoglobinopathies,  blood banking-transfusion medicine

 MEMBERSHIPS:

International Society of Haematology (ISH)

ASmerican Society of Hematology (ASH)

Association for  Medical Education in Europe (AMEE)

International Society on Thrombosis and Haemostasis (ISTH)

Ankara Thalassaemia Society

Turkish Society of Haematology

Blood Banks and Transfusion Society of Turkey

Haemophilia Society (Ankara)

 

ADMINISTRATIVE DUTIES AND RESPONSIBILITIES:

In University:

2019-…. : Member, University Curriculum Committee, Alfaisal University

2013-2015; 2017-.. : Chair, Curriculum Committee, College of Medicine, Alfaisal University

2011-…: Director of Clinical Clerkships and Internship, College of Medicine, Alfaisal University

2010-2011:     Vice –Dean (for Academic Afairs), Colege of Medicine, Al-Kharj University, Saudi Arabia  

1996-2000 and 2005-2008:  Vice Dean (for Education and Academic Affairs), Faculty of Medicine, Ankara University

1994-1996 and 2000-2003 : Member, Faculty Academic Board, Ankara University Faculty of Medicine

2003-2005 :  Member, Faculty Administrative Board, Ankara University Faculty of Medicine

1997-2009 :  Director, Serpil Akdağ Blood Centre, Ankara University

1996-2008 :  Member and Chairman, Undergraduate Education Coordination Committee, Ankara University Faculty of Medicine

1996-2000; 2005-2008: Member, Postgraduate Education Coordination Committee, Ankara University Faculty of Medicine

2003-2005   :  Year 3 Undergraduate Education Coordinator, Ankara University Faculty of Medicine

2002-2009 : Member, Educational Methods and Case Development Committee, Ankara University Faculty of Medicine

2002- 2009  : Member, Assessment and Evaluation Committee, Ankara University Faculty of Medicine

2007 -         :  Erasmus Coordinator, Ankara University Faculty of Medicine

2005 :          Member, ad hoc Committee for European University Association Self

Assessment Report, Ankara University Faculty of Medicine

2008 -           : Member, Bologna Process Coordination Committee, Ankara University

2005 - 2010 : Member, Academic Evaluation and Quality Improvement Committee, Ankara University

 

Outside the University (Scientific Societies and Groups)

2008 -       : Secretary General, European-African Division, International Society of Hematology

2002 -       : National Councillor,  International Sociaety of Hematology (representing Turkish Society of Hematology)

2007-2011     Member, Turkish National Accreditation Council for Medical Education; member of Standards Setting Committee.

2005-2007     : Member, Medical Education in EuropeMEDINE) Thematic Network

2007 -2008    : Member, European Pediatric Thematic Network (EUROPET)

2005-2009     : Member, Medical Education in Europe (MEDINE) Thematic Network

2007 - 2008  : President, Turkish Society of Pediatric Hematology

2001-2007    : Member, Administrative Board, Turkish Society of Pediatric Hematology

2004 - 2010  : Member of Administrative Board, Turkish Society of Medical Education   

2007 - 2008  : Member, European Pediatric Thematic Network (EUROPET)

2004 -            : Member, Board of Trustees, Turkish Blood Foundation

2004 - 2009 : Member, Ministry of Health Blood Services Advisory Board

2004 -  2009  : Member, Ministry of Health Scientific Committee of Blood Centres

2004 - 2009  : Member, Ministry of Health Commission for Hemapheresis and Photopheresis

1996-1997   :  Member,Administrative Board, Ankara Chamber of Physicians

 

EDITOR FOR SCIENTIFIC JOURNALS

Tıp Eğitimi Dünyası (“The World of Medical Education”-Turkish Journal of Medical Education) (2009-2024)    

Çocuk Hematoloji Dergisi (Turkish Journal of Pediatric Hematology)  (2009-2014   )

 

REFEREE FOR SCIENTIFIC JOURNALS

Medical Teacher
Medical Education Online
Interdisciplinary Journal of Problem Based Learning

Tıp Eğitimi Dünyası (Turkish Journal of Medical Education)

Turkish Journal of Pediatrics

Çocuk Sağlığı ve Hastalıkları Dergisi
Turkish Journal of Hematology
Çocuk Hematoloji Dergisi (Turkish Journal of Pediatric Hematology)

 

PUBLICATIONS:
A. International SCI Indexed Journals

1. Kemahlı S, Babacan E, Çavdar AO: Cell-mediated immune responses in children with iron deficiency and combined iron and zinc deficiency. Nutrition Research,1988; 8(3), 129-136.

2. Kemahlı S, Sarp N: The growth and development of children living in residential units (Children’s Homes) in Turkey. Maladjustment and Therapeutic Education, 1989; 7:163-168.

3. Canatan D, Erden İ, Aykaç S, Akar N, Kemahlı S, Arcasoy: Doppler colour flow imaging for the evaluation of postsplenectomy portal vein thrombosis in pediatric hematological diseases. Pediatric Hematology and Oncology, 1992; 9:297-399. 

4.Uysal Z, Akar N, Kemahlı S, Dinçer N, Arcasoy A: Desferrioxamine and urinary zinc excretion in b-thalassemia major. Pediatric Hematology  and Oncology,1993;10:257-260. 

5. Kemahlı S, Goldman E, McCraw A, Jenkins V, Kernoff PBA: Value of DNA analysis with multiple DNA probes for the detection of hemophilia A carriers. Pediatric Hematology and Oncology,1994; 11:55-62. 

6. Kemahlı S, Canatan D, Uysal Z, Akar N, Uysal Z, Cin Ş, Arcasoy A: DDAVP shortens bleeding time in Bernard-Soulier syndrome. Thrombosis and Haemostasis, 1994;71(5): 675. 

7. Suskan E, Kemahlı S, Atalay S, Ertogan F, Karademir S: Intracardiac thrombosis associated with acquired protein C deficiency. European Journal of Pediatrics, 1994; 153(11), 862-863. 

8. Kemahlı S, Canatan D, Uysal Z, Akar N, Cin Ş, Arcasoy A: GM-CSF in the tratment of Fanconi’s anaemia. British Journal of Haematology, 1994; 87:871-872. 

9. İnce E, Kemahlı S, Uysal Z, Akar N, Dinçer N, Cin Ş, Arcasoy A: Mild zinc deficiency in preschool children. The Journal of Trace Elements in Experimental Medicine,1995; 7: 135-141.

10. Yıldırmak Y, Kemahlı S, Akar N, Uysal Z, Cin Ş, Arcasoy A: A case of severe thrombocytopenia due to parvovirus B19 virus. Pediatric Hematology and Oncology, 1995; 13:183-185. 

11.Özdemir O, Gürsel T, Tangün Y, Dündar S, Yalçın A, Nişli G, Haspolat K, Kılınç Y, Ağaoğlu L, Patıroğlu T, Kemahlı S, Erduran E, Koçak R, Dinçer S, Canatan D, Yeşilipek A, Tanyer G, Özcan O, Tunalı A, Aydoğdu İ, Albayrak D: Turkish National Haemophilia Registry. Preliminary Report on Practice Pattern of Haemophilia Treatment. 1st National Haemophilia Congress, Ankara, 5-7 May 1997. Turkish Journal of Haematology, 14(3) Suppl, 3-8, 1997.

12.             Kemahlı S: Comprehensive Management of Haemophilia. 1st National Haemophilia Congress, Ankara, 5-7 May 1997.  Turkish Journal of Haematology, 14(3) Suppl, 8-11, 1997

13. Kemahlı S, Gürman C, Eğin Y, Akar N, Uysal Z, Cin Ş, Arcasoy A: Hypercoagulability in children with thalassemia major. Clinical and Applied Thorombosis/Hemostasis, 1997;3(2): 129-132. 

14. Kemahlı S, Uysal Z, Canatan D, Akar N, Cin Ş, Arcasoy A: Post-slenectomy thrombosis and haemolytic anaemias. British Journal of Haematogy 1997; 97(2): 505. 

15.  Kemahlı S, Alhenc-Gelas M, Gandrille S, Aiach M, Akar N,  Cin Ş: Homozygous Protein C Deficiency With A Double Variant His 202 To Tyr And Ala 346 To Thr. Blood Coagulation and Fibrinolysis,1998; 9:351-354. 

16.  Arcasoy A, Öcal G, Kemahlı S, Berberoğlu M, Yıldırmak Y, Canatan D, Akçurin S, Akar N, Uysal Z, Adıyaman P, Çetinkaya E: Recombinant human growth hormone treatment in children with thalassemia major. Pediatrics International, 1999; 41:655-661. 

17. Akar N, Kemahlı  S, Akar E, Mısırlıoğlu M, Uysal Z, Canatan D, Cin Ş: Common Genetic Variants in Patients with Chronic Hemolytic Disease and Post-splebectomy Thrombotic Events. Turkish Journal of Hematology 1999; 16(1): 41-42.

18.             Akar N, Kemahlı S, Akar E, Mısırlıoğlu M, Uysal Z, Canatan D, Cin Ş:Common genetic variants in patients with chronic hemolytic disease and post-splenectomy thrombotic events. Turkish Journal of Haematology, 16(1):41-42, 1999.

19.  Ekim N, Akar N,  Tutar E, Kemahlı S, Tümer N: Endothelin-1 and von Willebrand Factor in pseudoxanthoma elasticum. Pediatric Nephrology,2000; 14 (8-9): 882-3. 

20. Yıldırmak Y, Kemahlı S, Dinçer N, Hasanoğlu A, Biberoğlu G, Cin Ş, Arcasoy A: Hyperzincuria and selective amino aciduria in thalassemia. Journal of Trace Elements in Experimental Medicine,2000; 13: 199-204. 

21. Akar N, Kemahlı S, Deda G, Akar E, Yılmaz E, Uysal Z, Cin Ş: Multiple cerebral emboli in a homozygous b-thalassaemia patient due to factor V 1299 (His-Arg) 4070 A-G mutation. Turkish Journal of Haematology, 2000; 17(3): 133-136.

22. Yenice Ş, Kemahlı S, Bilenoğlu O, Gül Ö, Akar E, Başak AN, Akar N: Two rare hemoglobin variants in the Turkish population (HbG-Coushatta(B22(B+) GU-ALA and HbJ Iran (B77(EF1)HIS-ASP). Turkish Journal of Hematology, 2000; 17: 27-27.

 

23. Dalyan M, Tuncer S, Kemahlı S: Hemophilic arthropathy: evaluation of clinical and radiological characteristics and disability. Turkish Journal of Pediatrics, 2000; 42: 205-209.

24. Kemahli S. Clinical teaching and OSCE in pediatrics. Med Educ Online [serial online] 2001;6:10. Available from URL http://www.med-ed-online.org

25.Manco-Johnson MJ, Grabowski EF, Hellgreen M, Kemahli AS, Massicotte MP,  Muntean W, Peters M, Nowak-Göttl U: Laboratory Testing for Thrombophilia in Pediatric Patients. Thrombosis and Haemostasis, 2002; 88:155-156. 

26.  Manco-Johnson MJ, Grabowski EF, Hellgreen M, Kemahli AS, Massicotte MP,Muntean W,Peters M, Schlegel N, Wang M, Nowak-Göttl U. Recommendations for tPA Thrombolysis in Children. Thrombosis and Haemostasis, 2002; 88:157-158. 


27. Onay V, Kavaklı K, Kılınç Y, Gürgey A, Aktuğlu G, Kemahlı S, Özbek U, Çağlayan H: Molecular pathology of haemophilia B in Turkish patients: identifiation of a large deletion and 33 independent point mutations. British Journal of Haematology, 2003; 120:656-659. 

28. Atasay B, Arsan S, Günlemez A, Kemahlı S, Akar N: Factor V Leiden and prothrombin gene 20210A variant in neonatal thromboembolism and in healthy neonates and adults. Study in a single center. Pediatric Hematology and Oncology, 2003; 20: 627-634. 

29. Kemahlı S, Dökmeci F, Palaoğlu Ö, Aktuğ T, Arda B, Demirel-Yılmaz E, Karahan T, Özyurda F, Akan H, Ayhan İH: How we derived a core curriculum: from institutional to national-Ankara University experience. Medical Teacher, 2004; 26: 295-298.  

30. Kavaklı K, Aktuğlu G, Kemahlı S, Devecioğlu O:  Inhibitor screening project for patients with hemophilia in a developing country: Turkey. Haemophilia 2004; 10, (Suppl. 3), 58. 

31. Uçar T, Gürman C, Arsan S, Kemahlı S: Platelet aggregation in term and preterm newborns. Pediatric Hematology and Oncology, 2005; 22:139-145. 

32. İkincioğulları A, Doğu F, Solaz N, Reisli İ, Kemahlı S, Cin Ş, Babacan E: Granulocyte transfusions in children with chronic granulomatous disease and invasive aspergillosis. Therapeutic Apheresis and Dialysis, 2005; 9(2): 137-141.

33. Kemahlı S:Hematology education in a problem-based curriculum. Hematology, 2005;10 Suppl 1:161-163. 

 

34. Kavaklı K, Aktuğlu G, Kemahlı S, Başlar Z, Ertem M, Balkan C, Arr C, Yılmaz Karapınar D,  Bilenoğlu B,  Gülseven M, Gürman C: Inhibitor screening for patients with hemophilia in Turkey. Turk J Hematol 2006;23(1): 25-32

35. Demirören M, Palaoğlu, Ö, Kemahlı S, Özyurda F Ayhan HI. Perceptions of students in different phases of medical education of educational

environment: Ankara University Faculty of Medicine. Med Educ Online [serial online] 2008;13:8 doi;10.3885/meo.2008.Res00267

Available from http://www.med-ed-online.org

36. Acar A, Kemahlı S, Altunay H, Koşan E, Öncül O, Görenek L, Çavuşlı Ş: HBV, HCV and HIV seroprevalence among blood donors in Istanbul, Turkey: how effective are the changes in the national blood transfusion policies? Brazilian Journal of  Infectious Diseases 2010;14: 41-46.

37. Acar A, Kemahlı S, Altunay H, Koşan E, Öncül O, Görenek L, Çavuşlu Ş. The significance of repeat testing in Turkish blood donors  screened with HBV,   HCV    and HIV immunoassays and the importance of S/CO ratios in the interpretation of HCV/HIV screening test results and as a determinant for further confirmatory testing. Transfusion Medicine, 2010, 20, 152–159.

 

38. Demirören M, Aytuğ-Koşan AM, Palaoğlu Ö, Aktuğ T, Kemahlı S: Self-perceptions of problem-based curriculum graduates about their professional competency and quality of medical education. Medical Teacher 2010;32(12):1010-1011.

 

39. Sahyoun-Tokan R, Arsan S, Erdeve Ö, Solaz N, Avcı A, Elgün-Ülkar S, Gülyapar E, Üstünyurt Z, Bıyıklı Z, Kemahlı S:  Comparison of stored umbilical cord blood with donated adult blood: a study for transfusion feasibility. Turk J Hematol , 2012; 29:233-241.

 

40. Palaoğlu Ö, Demirören M, Aytuğ-Koşan AM, Kemahlı S: Core curriculum policy analysis in medical education. MedEdWorld Publish. www.mededworld.org 2012. http://www.mededworld.org/getattachment/MedEdWorld-Papers/Papers-Items/Core-Curriculum-Policy-Analysis-in-Medical-Educati/MedEdWorld-CORE-CURRICULUM-POLICY-IN-MEDICAL-EDUCATION.pdf.aspx

 

41. Karakoc AE, Berkem R, Irmak H, Demiroz AP, Yenicesu I, Ertugrul N, Arslan Ö, Kemahli S, Yilmaz S, Ozcebe O, Kara A, Ozet G, Acikgoz ZC, Acikgoz T. Investigation of an algorithm for HCV EIA reactivity in blood donor screening in Turkey in the absence of nucleic acid amplification screening Transfus Apher Sci. 2017 Sep 8. pii: S1473-0502(17)30176-3. doi: 10.1016/j.transci.2017.08.025. [Epub ahead of print]

 

42.  Ganguly P, Yaqinuddin A, AlKattan W, Kemahlı S, AlKattan K. Medical education dilemma: How can we best accommodate basic sciences in a curriculum for 21st century medical students? Canadian Journal of Physiology and Pharmacology, 2019, 97(4): 293-296.  https://doi.org/10.1139/cjpp-2018-0428

 

 

43. Farah, Roula A.; Mitri, Aida1; El Rahi, Hiba; Al Humaidan, Hind2; Rajab, M. Hasan3; Kemahli, Sabri3. Knowledge of blood transfusion practices among medical students and residents. Asian Journal of Transfusion Science 18(1):p 51-55, Jan–Jun 2024. | DOI: 10.4103/ajts.ajts_150_21).

44. Kemahli, S., Alkattan, W. Alkattan, K., Ganguly, P.  Dilemma in Medical Education: who is a good medical teacher? South-East Asan Journal of Medical Education, 2022; 26: 20-23.  DOI: 10.4038/seajme.v16i1.404

45.

.

 

B. Publications in refereed National Journals:

  1. Kemahlı S: Yetersiz Beslenmede Bağışıksal Durum. Romatizma, 2(5):139-156, 1978.
  2. Cin Ş, Kemahlı S, Doğu Ü, Demirağ B: Son 10 yılda izlenen ampiyem olgularımız. Ankara Tıp Bülteni, 1(3): 255-164, 1979.
  3. Akar N, Kemahlı S, Abal G: Factors influencing the duration of breast feeding in Ankara. Ankara Tıp Bülteni, 4(3), 201-206, 1982.
  4. Kemahlı S, Oğur G, Turhanoğlu İ, Uluoğlu Ö, Timlioğlu B, Gürel M: Retroperitoneal endodermal sinüs tümörü (sarı kese tümörü). Tümay SB, Cenani A, Yalçın E(ed.):XXI. Türk Pediatri Kongresi . Pediatrik Nöroloji. İstanbul, 5-9 Temmuz 1982. Türk Pediatri Kurumu Yayınları. Özlem Kardeşler Matbaası, İstanbul 1983. s.:531-535.
  5. Kemahlı S, Oğur G, Turhanoğlu İ, Berki  R, Dinçer S, Öcal G, Laleli Y: Bir erkek yalancı hermafroditizm olgusu: psödovaginal perineoskrotal hipospadias. Tümay SB, Cenani A, Yalçın E (ed.): XXI. Türk Pediatri Kongresi. Pediatrik Nöroloji. İstanbul, 5-9 Temmuz 1982. Türk Pediatri Kurumu Yayınları. Özlem Kardeşler Matbaası, İstanbul 1983. s.:349-353.
  6. Kemahlı S, Sarp N: Yuva çocuklarının sağlık sorunlarının sağlık sorunları. Çocuk Hastalıkları Dergisi, 2(3): 155-159, 1987.
  7. Kemahlı S, Evlat edinilmenin çocukta büyümeye etkisi. A.Ü. Tıp Fakültesi Mecmuası, 40(4), 279-284, 1987.
  8. Kemahlı S, Babacan E, Çavdar AO: saf demir eksikliği ile demir-çinko eksikliğinde hücresel bağışıklık. Ulutin O, Kılıçturgay K ve ark. (ed.): Hematoloji-1987-IX. Uycan Basımevi, İstanbul, 1988.s.:571-576.
  9. Kemahlı S, Kunak B, Kantaroğlu N: Bir Çocuk yuvasında HBsAg ve Anti-HBs taraması sonuçları. Çocuk Sağlığı ve Hastalıkları Dergisi, 31:11-116,1988.
  10. Kemahlı S, Gökdoğan S, Bulut B, Arcasoy A: Deniz mavisi histiosit sendromu (Sea-blue histiosit sendromu). A.Ü.Tıp Fakültesi Mecmuası, 43:453-458, 1990.
  11. Bulut B, Kemahlı S, Kanamalı hastalıkların tedavisinde desmopressin kullanımı. Türkiye Klinikleri Tıp Bilimleri Dergisi, 12: 162-171,1992.
  12. Canatan D, Dağdemir A, Kemahlı S, Akar N, Cin Ş, Arcasoy: İmmün trombositopenik purpura (86 olgunun izlem ve tedavisi) . Türkiye Klinikleri Pediatri Dergisi, 1:54-57, 1992.
  13. Canatan D, Uysal Z, Kemahlı S, Akar N, Cin Ş, Arcasoy A: Herediter sferositoz (22 olguda klinik özellikler, komplikasyonlar ve tedavi). A.Ü. Tıp Fakültesi Mecmuası, 46: 101-108, 1993.
  14. Canatan D, Uysal Z, Akar N, Kemahlı S, Cin Ş, Arcasoy A: Akrodermatitis enteropatika. A.Ü. Tıp Fakültesi Mecmuası, 46:677-686, 1993.
  15. Canatan D, Arcasoy A, Öcal G, Tutat E, Akar N, Kemahlı S, Uysal Z, Cin Ş:  Multipl endokrin komplikasyonlar olan bir thalassemia major olgusu. Türkiye Klinikleri Pediatri, 2:205-208, 1993.
  16. Arcasoy A, Turan F, Yeşil N, Kemahlı S, Canatan D, Uysal Z, Canatan D, Akar N: Muğla ili ve çevresinde thalassemia ve anormal hemoglobin sıklığının taraması. Pediatride Yönelişler, 1(2): 78-80, 1994
  17. Kemahlı S, Canatan D, Erden İ, Aytaç S, Uysal Z, Akar N, Konkan R, Yücesan S, Barlas M, Dindar H, Cin Ş, Arcasoy A: Hemolitik anemilerde splenektomi sonrası tromboz. A.Ü. Tıp Fakültesi Mecmuası, 47:605-612, 1994.
  18. Canatan D, Uysal Z, Kemahlı S, Gözdaşoğlu S, Cin Ş, Arcasoy A, Akar N: Fanconi’s aplastic anemia ( Presentation and treatment of 21 cases). Journal of Ankara Medical School, 16:1001-1007, 1994.
  19. Canatan D, Kemahlı S, Cin Ş, Öcal G, Akar N, Arcasoy A: Hereditary elliptocytosis with growth hormone and gonadotropin deficiency. Journal of Ankara Medical School, 16:1019-1022, 1994.
  20. Kemahlı S, Akar N, Öcal G: Faktör VII eksikliği ile birlikte olan bir Noonan sendromu. Pediatride Yönelişler, 1(7): 114-116, 1995.
  21. Sipahi T, Akar N, Kemahlı S, Uysal Z, Cin Ş, Arcasoy A: Çocuklarda edinsel aplastik anemi ve tedavisi (22 olgunun değerlendirilmesi) Klinik Bilimler-Pediatride Yönelişler, 2:11-13, 1996.
  22. Sipahi T, Kemahlı S, Kır M, Binnet M, Tuncer S, Cin Ş, Arcasoy A: Hemofilide radyonüklid sinovektomi: olgu sunusu. Klinik Bilimler-Pediatride Yönelişler, 2:47-48, 1996.
  23. Yıldırmak Y, Kemahlı S, Canatan D, Arcasoy A, Cin Ş: Çocukluk yaşlarında otoimmün hemolitik anemiler. Klinik Bilimler-Pediatride Yönelişler, 2(7): 94-98, 1996.
  24. Özdemir O, Gürsel T, Tangün Y, Dündar S, Yalçın A, Nişli G, Haspolat K, Kılınç Y, Ağaoğlu L, Patıroğlu T, Kemahlı S, Erduran E, Koçak R, Dinçer S, Canatan D, Yeşilipek A, Tanyer G, Özcan O, Tunalı A, Aydoğdu İ, Albayrak D: Turkish National Haemophilia Registry. Preliminary Report on Practice Pattern of Haemophilia Treatment. 1st National Haemophilia Congress, Ankara, 5-7 May 1997. Turkish Journal of Haematology, 14(3) Suppl, 3-8, 1997.
  25. Kemahlı S: Comprehensive Management of Haemophilia. 1st National Haemophilia Congress, Ankara, 5-7 May 1997.  Turkish Journal of Haematology, 14(3) Suppl, 8-11, 1997
  26. Tekin M, Kemahlı S, Trombopoetin  ve Trombopoez. Turkish Electronic Journal of Medicine, 1(1), 1997. (http://www.ato.org.tr/tejm.htm)
  27. Kemahlı S: Çocuklarda tromboz profilaksisi ve antitrombotik tedavi. Prospekt, 2: 80-86, 1998.
  28. Akar N, Kemahlı S, Akar E, Mısırlıoğlu M, Uysal Z, Canatan D, Cin Ş:Common genetic variants in patients with chronic hemolytic disease and post-splenectomy thrombotic events. Turkish Journal of Haematology, 16(1):41-42, 1999.
  29. Pasin M, Fıçıcılar H, Tekin D, Tekin M, Yavuzer S, Akar N, Kemahlı S, Arcasoy A:  Beta-Thalassemia majorda trombosit fonksiyonlarına yeni bir yaklaşım. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 1999,52(4):205-209.
  30. Deda G, Askar N, Kemahlı S, Uysal S, Güven A, Kabakuş N, Karagöl U: Cerebrovascular accidents and the role of factor V mutation in children. Journal of Ankara Medical School, 1999,21:147-150
  31. Kemahlı S: Hastane Transfüzyon Komiteleri. Klinik Gelişim, 14:138-140, 2001.
  32. Cin Ş, Kemahlı S, Solaz N: Blood banking and transfusion medicine education in undergraduate medical students (A model proposal). Blood Banking And Transfusion Medicine, 2003; 1: 89-92.
  33. Kemahlı S: Transfusion indications for acute anemias. Blood Banking and Transfusion Medicine, 2003; 1(Suppl. 1): S67-69.
  34. Şimşek F, Öztürk G, Kemahlı S, Erbaş D, Hasanoğlu A: Oxidant and antioxidant status in beta thalassemia major patients. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2005; 58: 34-38.
  35. Kemahlı A, Alper A: Probleme Dayalı Öğrenmeye Yönelik Tutum Ölçeği, Eğitim Bilimleri ve Uygulama, 2006;5:191-206.
  36. Kemahlı S: Tıp Eğitimi ve Hekimlik Dilimiz Nasıl Türkçeleşti? Tıp  Eğitimi Dünyası, 2015; 14 (44): 5-12.

 

  1. Tamimi HE, Nurhussen A, Rohra D Ouban A, AlShadoukhy A, AlKattan W, Kemahlı S. Student Ratings For Vertical Integration Sessions In Clinical Clerkships. Tıp Eğitimi Dünyası , 2018; 17 (52): 27-34. http://dx.doi.org/10.25282/ted.397608

 

 

 

 

 

 

 

C) BOOK CHAPTERS:  
1. Kemahlı S: Thalassemiada komplikasyonlar ve tedavisi. [Arcasoy A (editör):  “Thalassemiada Tedavi” içinde.] Ankara Thalassemia Derneği  Yayınları. Ankara Üniversitesi Basımevi. Ankara, 1994. 

2. Kemahlı S: Kanamalı Hastaya Yaklaşım. [İN.Cin Ş (Editör): “Pediatrik Aciller”]. Ankara Üniversitesi Tıp Fakültesi Bilimsel Yayınlar Serisi No:6. Antıp A.Ş., Ankara, 1995.s:107-122. 

3. Kemahlı S: Kanamalı hastalıklara yaklaşım ve hemofililer. [in: Cin Ş (editör):” Çocuk Hastalıkları ders kitabı” içinde]. Ankara Üniversitesi Tıp Fakültesi Bilimsel Yayınlar Serisi No:8. Antıp A.Ş., Ankara, 1995, 1995. S: 376-390.

4. Kemahlı S: Çocuklarda Hematolojik Parametreler. (in: Klinik Bilimlere Giriş VII-Çocuk Sağlığı ve Hastalıkları” . Ankara Üniversitesi Tıp Fakültesi Bilimsel Yayınlar Serisi No:1. Antıp A.Ş., Ankara 1997. S:271-27

 

5. Kemahlı S: Yenidoğanlarda Fibrinolitik Sistem. [in: Ulutin O, Cin ş. (editör): “Neonatal Hemostaz ve Tromboz”] Ankara, 1999. s:13-17.

6. Kemahlı S: Pıhtılaşma Faktör Bozuklukları ve Tromboz. [in: “Çocuk Hastalıkları”].Ankara Üniversitesi Tıp Fakültesi Antıp A.Ş. yayınları, Ankara, 2004,  S: 745-749

7. Kemahlı S: Transfüzyona Bağlı Eritrosit Alloimmünizasyonu. [in: Uysal Z, Solaz N,   Kemahlı S, Aydınok Y, Ertem M, Atasay B: Pediatride Kan ve Kan Ürünleri Kulanımı]. Çocuk Hastalıkları Araştırma Vakfı Yayını, Ankara, 2005.

 

8. Kemahlı S, Mazhar A, Qazi S, Shaikh A, Fatima T, Ganguly P: What is the best assessment system in anatomy?  In: Ganguly P (editor): Education in Anatomical Sciences,  Nova Science Publishers, New York, 2013. pp:191-212.

 

9. Kemahlı S: Integration is the Key. In: Ganguly P (editor).Health and Disesase-Curriculum for the 21st Century Medical Students, Nova Science Publishers, New York, 2014. pp:65-77.

 

10. Kemahlı AS. Tıp eğitiminde yapay zekâ.(Artifical Intellligence in Medical Education) Ekmekci PE, editör. Yapay Zekâ ve Tıp Etiği. 1.Baskı. Ankara: Türkiye Klinikleri; 2020. p.25-8.

 

11. Kemahlı S (editor): Clinical Training in Undergraduate Medical Education. ISBN: 978-1-53618-616-1. Nova Science Publishers, NY, USA. 2020

12. Kemahlı S. Principles of Professional Clinical Training. In: Kemahlı S (editor): Clinical Training in Undergraduate Medical Education. pp:1-12. ISBN: 978-1-53618-616-1. Nova Science Publishers, NY, USA. 2020.

 

13.  Kemahlı S, AlKattan K, AlKattan W: Structuring Clinical Clerkships. In: Kemahlı S (editor): Clinical Training in Undergraduate Medical Education. pp:95-106 ISBN: 978-1-53618-616-1. Nova Science Publishers, NY, USA. 2020

 

14.  Şahiner M, Demirören M, Kemahlı S: Models and Methods of Teaching and Learning in Clinical Clerkships. In: Kemahlı S (editor): Clinical Training in Undergraduate Medical Education. pp: 165-184. ISBN: 978-1-53618-616-1. Nova Science Publishers, NY, USA. 2020.

 

15.  Çalışkan SA, Şenol Y, Kemahlı AS. Designing and Organizing Assessment in Clinical Clerkships. In: Kemahlı S (editor): Clinical Training in Undergraduate Medical Education. pp: 255-269. ISBN: 978-1-53618-616-1. Nova Science Publishers, NY, USA. 2020.

16.  Kemahlı S: Public education for the prevention of thalassemia and hemoglobinopathies.In: Canadan D (Editor): Thalassemia and Hemoglobinopathies. Diagnosis, Therapy and Prevention.  Pp:464-469.                                     ISBN: 978-625-371-028-6. E-ISBN:9798-625-371-029-3. Nobel Akademik Yayıncılık. 2024.

 

 

 

LECTURES IN INTERNATIONAL MEETINGS (Except Short Communications)

 

  1. Transfusion Indications for Acute Anemias. International Society of Blood Transfusion (ISBT) Regional Congress, July  2003, İstanbul.
  2. Health politics and medical education in Turkey. 1 June 2007, EUROPET Meeting, Gelsenkirchen, Germany.
  3. Considerations when planning an accreditation system. AMEE Congress, September 2007, Trondheim, Norway.
  4. Pediatric curriculum in Turkey (Undergraduate and Specialty). EUROPET Meeting, 20 October 2007, Cluj-Napoca, Rumania.
  5. Contemporary Trends in Medical Education.  7th Scientific Conference for Medical Students in the GCC Countries. 13-16 February 2010, Jeddah, Saudi Arabia.
  6. Workshop on Implementation and Management of Integrated Curricula (with Professor Ronald Harden) SIMEC- Saudi International Medical Education Conference, Jazan, Saudi Arabia, April 2010.
  7. Integration in Undergraduate Education with Special Reference to Hematology. XXXVth World Congress of the International Society of Hematology. 4-7 September 2014, Beijing, China.
  8. Current Perspectives on Undergraduate Hematology Education. IVth Pan-Arab Hematology Congress. 5-7 February 2015, Abu Dhabi, UAE.
  9. Undergraduate Hematology Education. 9th Regional  Meeting of The Lebanese Society of Hematology amnd Blood Transfusion. 1-3 October 2015, Beirut, Lebanon.
  10. "Undergraduate Hematology Education". 38th World Congress of the International Society of Hematology; 64th National Congress of Spanish Society of Hematology and Hemotherapy and 38th National Congress of Spanish Society of Thrombosis and Hemostasis.6-8 October 2022, Barcelona, Spain.

11.    "Hemovigilance in Hematopietic Stem Cell Tranplantation” 39th World Congress of the International Society of Hematology (ISH) and XIIth Mexican Congress on Bone Marrow Transplantation. 29-31 August 2024, Monterrey, Mexico.

 

 

 

SUPERVISION FOR THESES  (THESIS ADVISOR/SUPERVISOR)

For specialty theses (Pediatrics):

  1. Yiğit, Şevket: Yenidoğanlarda fibrinolitik sistemin değerlendirilmesi  (Assessment of fibrinolytic system in newborns). (1996)
  2. Uçar, Tayfun: Term ve preterm yenidoğanlarda trombosit agregasyonu. (Platelet aggregation in term and preterm newborns) (2001)
  3. Tokan, Rola: Term ve Preterm yenidoğanlarda transfüzyon amaçlı hazırlanan otolog kordon kanının özelliklerin etkileyen faktörlerin belirlenmesi, çok düşük doğum ağırlıklı pretermlerin anemisinde otolog kordon kanı transfüzyonunun etkinliğinin ve güvenilirliğinin araştırılması. (Assessing  the factors  determining the characteristics of autologous cord blood prepared for transfusion and investigation of the eComparison of stored umbilical cord blood with donated adult blood: a study for transfusion feasibility).Assessment of the factors       (2008)

 

Masters theses (Masters programme for Blood Banking and Transfusion Medicine):

1.       Solaz, Nuri: Gebeler ve yakınlarında kan gruplaması alloimmünizasyon riski olan gebelerin izlenmesinde otolog kordon kanı transfüzyonunun etkinliğinin ve güvenilirliğinin araştırılması (2003)

2.       Aksoy, Armağan: Kan komponentlerinde bakteriyel kontaminasyon oranlarının araştırılması. (2005)

3.       Tulunay, Eda Ayşe: Kan bağışçılarının ve bir kamu kurumu çalışanlarının kan bağışına ilgisi, bilgi düzeyleri ve ulusal yeterliliğe ulaşma yöntemleri. (2007)

4.       Acar, Ali: Kan bağışçılarında HBV, HCV, HIV tarama testlerinin doğrulanması: tarama testlerinin pozitif prediktivitesi ve doğrulama testlerinin maliyeti. (2008)

5.       Aytuğ-Koşan, Ayşen Melek: PDÖ sürecinde küçük grup çalışmalarındaki grup aksaklıklarına ilişkin eğitici ve öğrenci görüşlerinin belirlenmesi. (2008)

6.       Yenicesu, İdil: Mevsimlerin ve sigara kullanımının donör red nedenleri üzerine etkisi; Türkiye için ne kadar önemlidir? (2009)

7.       Uyanık, Haluk: Donör kazanım çalışmalarının kan bağış oranına etkilerinin değerlendirilmesi (2010)

 

CV

Publications

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Student Ratings For Vertical Integration Sessions In Clinical Clerkships

Journal Article ,
Student Ratings For Vertical Integration Sessions In Clinical Clerkships. (2018). Tıp Eğitimi Dünyası 52 (52), 27-34, 2018.

Investigation of an algorithm for anti HCV EIA reactivity in blood donor screening in Turkey in the absence of nucleic acid amplification screening

Journal Article ,
Investigation of an algorithm for anti HCV EIA reactivity in blood donor screening in Turkey in the absence of nucleic acid amplification screening. (2017). Transfusion and Apheresis Science 56 (5), 732-737, 2017.

TIP EĞİTİMİ VE HEKİMLİK DİLİMİZ NASIL TÜRKÇELEŞTİ?

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TIP EĞİTİMİ VE HEKİMLİK DİLİMİZ NASIL TÜRKÇELEŞTİ?. (2015). Tıp Eğitimi Dünyası 14 (44), 5-12, 2015.

Comparison of stored umbilical cord blood and adult donor blood: transfusio feasibility

Journal Article ,
Comparison of stored umbilical cord blood and adult donor blood: transfusio feasibility. (2012). TUrkish Journal of Hematology, 29, 233-241.

Core curriculum policiy analysis in medical education

Journal Article ,
Core curriculum policiy analysis in medical education. (2012). MedEdWorld.

Comparison of stored umbilical cord blood and adult donor blood: transfusion feasibility

Journal Article ,
Comparison of stored umbilical cord blood and adult donor blood: transfusion feasibility. (2012). Turkish Journal of Hematology 29 (3), 233, 2012.

Core curriculum policy analysis in medical education

Journal Article ,
Core curriculum policy analysis in medical education. (2012). AMEE MedEdPublish 1 (1), 2012.

De in het groot Stoel van de Massage Spoor SL Functie Rol Voet Douane Volledige Lichaam Geneigde Multi Intelligente met Bluetooth

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De in het groot Stoel van de Massage Spoor SL Functie Rol Voet Douane Volledige Lichaam Geneigde Multi Intelligente met Bluetooth. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Groene thee verticale stand Vffs verpakkingsmachine

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Groene thee verticale stand Vffs verpakkingsmachine. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Het Vervangstuk van de Schijf 0501332095 Koppeling voor Transmissie zF 4wg180/4wg200

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Het Vervangstuk van de Schijf 0501332095 Koppeling voor Transmissie zF 4wg180/4wg200. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

295 Evaluation of the Efficacy and Safety of Autologous Cord Blood Transfusions in Very Low-Birth-Weight Premature Newborns

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295 Evaluation of the Efficacy and Safety of Autologous Cord Blood Transfusions in Very Low-Birth-Weight Premature Newborns. (2010). Pediatric Research 68 (1), 152-152, 2010.

De gloednieuwe CNC Machine van de Draad EDM

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De gloednieuwe CNC Machine van de Draad EDM. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Van het zink van de Legering Hand Spinner s R188 Kogellagers Rotaties 3+-Notulen

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Van het zink van de Legering Hand Spinner s R188 Kogellagers Rotaties 3+-Notulen. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

80~ 210W/Mk het Nitride van Aluminium Ceramisch voor de Apparatuur Macht

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80~ 210W/Mk het Nitride van Aluminium Ceramisch voor de Apparatuur Macht. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Niet-toeneemt Kleppen van de Poort het Mes Stam Veerkrachtige Zachte Verzegelde met Toestel Worm

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Niet-toeneemt Kleppen van de Poort het Mes Stam Veerkrachtige Zachte Verzegelde met Toestel Worm. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Ylw Masker in KN95 Stock Mask met snelle verzending

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Ylw Masker in KN95 Stock Mask met snelle verzending. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

De Laminering Shichao2707 van de stator voor Stator Od128. 5mm

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De Laminering Shichao2707 van de stator voor Stator Od128. 5mm. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

HBV, HCV and HIV seroprevalence among blood donors in Istanbul, Turkey: how effective are the changes in the national blood transfusion policies?

Journal Article ,
HBV, HCV and HIV seroprevalence among blood donors in Istanbul, Turkey: how effective are the changes in the national blood transfusion policies?. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Het hydraulische Graafwerktuig Sy135 van de Breker Rots in Hete Ver koop Voorraad

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Het hydraulische Graafwerktuig Sy135 van de Breker Rots in Hete Ver koop Voorraad. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Self-perceptions of problem-based curriculum graduates about their professional competency and quality of medical education

Journal Article ,
Self-perceptions of problem-based curriculum graduates about their professional competency and quality of medical education. (2010). Medical Teacher 32 (12), 1010-1011, 2010.

The significance of repeat testing in Turkish blood donors screened with HBV, HCV and HIV immunoassays and the importance of S/CO ratios in the interpretation of HCV/HIV …

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The significance of repeat testing in Turkish blood donors screened with HBV, HCV and HIV immunoassays and the importance of S/CO ratios in the interpretation of HCV/HIV …. (2010). Transfusion Medicine 20 (3), 152-159, 2010.

Vuller Diep Ha van de Vergroting Jawlines Kin Skinject In het groot Hyaluronic Zure

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Vuller Diep Ha van de Vergroting Jawlines Kin Skinject In het groot Hyaluronic Zure. (2010). Brazilian Journal of Infectious Diseases 14 (1), 41-46, 2010.

Perceptions of students in different phases of Medicai education of educational environment: Ankara University Facuity of medicine

Journal Article ,
Perceptions of students in different phases of Medicai education of educational environment: Ankara University Facuity of medicine. (2008). Medical Education Online 13 (1), 4477, 2008.

Kan bağışçılarının ve bir kamu kurumu çalışanlarının kan bağışına ilgisi, bilgi düzeyleri ve ulusal yeterliliğe ulaşma yöntemleri

Journal Article ,
Kan bağışçılarının ve bir kamu kurumu çalışanlarının kan bağışına ilgisi, bilgi düzeyleri ve ulusal yeterliliğe ulaşma yöntemleri. (2007). Yayınlanmamış Yüksek Lisans Tezi, 2007.

ANKARA ÜNİVERSİTESİ TIP FAKÜLTESİNDE TIP EĞİTİMİNE BAŞLAYAN ÖĞRENCİLERİN ÖĞRENME STİLLERİ

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ANKARA ÜNİVERSİTESİ TIP FAKÜLTESİNDE TIP EĞİTİMİNE BAŞLAYAN ÖĞRENCİLERİN ÖĞRENME STİLLERİ. (2007). Tıp Eğitimi Dünyası 25 (25), 1-9, 2007.

PROBLEME DAYALI ÖĞRENMEYE YÖNELİK TUTUM ÖLÇEĞİ.

Journal Article ,
PROBLEME DAYALI ÖĞRENMEYE YÖNELİK TUTUM ÖLÇEĞİ. (2006). Journal of Educational Sciences & Practices 5 (10), 2006.

Inhibitor screening for patients with hemophilia in Turkey

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Inhibitor screening for patients with hemophilia in Turkey. (2006). Turk J Hematol 23 (1), 25-32, 2006.

Beta talasemi major hastalarinda oksidan ve antioksidan düzeyleri

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Beta talasemi major hastalarinda oksidan ve antioksidan düzeyleri. (2005). Ankara Üniversitesi Tıp Fakültesi Mecmuası 58 (1), 34-38, 2005.

Hematology education in a problem-based curriculum

Journal Article ,
Hematology education in a problem-based curriculum. (2005). Hematology 10 (sup1), 161-163, 2005.

Granulocyte transfusions in children with chronic granulomatous disease and invasive aspergillosis

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Granulocyte transfusions in children with chronic granulomatous disease and invasive aspergillosis. (2005). Therapeutic Apheresis and Dialysis 9 (2), 137-141, 2005.

DAHİLİ BİLİMLER/MEDICAL SCIENCES

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DAHİLİ BİLİMLER/MEDICAL SCIENCES. (2005). Journal of Ankara University Faculty of Medicine 58 (1), 2005.

Platelet aggregation in term and preterm newborns

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Platelet aggregation in term and preterm newborns. (2005). Pediatric Hematology and Oncology 22 (2), 139-145, 2005.

How we derived a core curriculum: from institutional to national—Ankara University experience

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How we derived a core curriculum: from institutional to national—Ankara University experience. (2004). Medical Teacher 26 (4), 295-298, 2004.

Analysis of pediatric thrombotic patients in Turkey

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Analysis of pediatric thrombotic patients in Turkey. (2004). Pediatric Hematology and Oncology 21 (7), 573-583, 2004.

Molecular pathology of haemophilia B in Turkish patients: identification of a large deletion and 33 independent point mutations

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Molecular pathology of haemophilia B in Turkish patients: identification of a large deletion and 33 independent point mutations. (2003). British Journal of Haematology 120 (4), 656-659, 2003.

Factor V Leiden and prothrombin gene 20210A variant in neonatal thromboembolism and in healthy neonates and adults: a study in a single center

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Factor V Leiden and prothrombin gene 20210A variant in neonatal thromboembolism and in healthy neonates and adults: a study in a single center. (2003). Pediatric Hematology and Oncology 20 (8), 627-634, 2003.

Clinical teaching and OSCE in pediatrics

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Clinical teaching and OSCE in pediatrics. (2001). Medical Education Online 6 (1), 4531, 2001.

Hyperzincuria and selective aminoaciduria in thalassemia

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Hyperzincuria and selective aminoaciduria in thalassemia. (2000). JOURNAL OF TRACE ELEMENTS IN EXPERIMENTAL MEDICINE 13 (2), 199-204, 2000.

Two Rare Hemoglobin Variants in the Turkish Population (Hb G-Coushatta (B 22 (B4) GLU-ALA and Hb J Iran (B 77 (EF1) HIS-ASP).

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Two Rare Hemoglobin Variants in the Turkish Population (Hb G-Coushatta (B 22 (B4) GLU-ALA and Hb J Iran (B 77 (EF1) HIS-ASP). (2000). Turkish Journal of Haematology: Official Journal of Turkish Society of …, 2000.

Multiple cerebral emboli in a homozygous b-thalassaemia patient due to factor V 1299 (His-Arg) 4070 AG mutation

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Multiple cerebral emboli in a homozygous b-thalassaemia patient due to factor V 1299 (His-Arg) 4070 AG mutation. (2000). Turk J Haematol 17 (3), 133-136, 2000.

Adress for Correspondence: Nejat AKAR, MD Konutkent-2, C-1 Blok, B-Giriş Daire 2 06530, Çayyolu, Ankara, TURKEY

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Adress for Correspondence: Nejat AKAR, MD Konutkent-2, C-1 Blok, B-Giriş Daire 2 06530, Çayyolu, Ankara, TURKEY. (2000). Turk J Haematol 17 (3), 133-136, 2000.

Endothelin-1 and von Willebrand factor in pseudoxanthoma elasticum.

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Endothelin-1 and von Willebrand factor in pseudoxanthoma elasticum. (2000). Pediatric Nephrology (Berlin, Germany) 14 (8-9), 882-883, 2000.

Recombinant human growth hormone treatment in children with thalassemia major

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Recombinant human growth hormone treatment in children with thalassemia major. (1999). Pediatrics International 41 (6), 655-661, 1999.

Cerebrovascular accidents and the role of factor V mutation in children

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Cerebrovascular accidents and the role of factor V mutation in children. (1999). Journal of Ankara Medical School 21 (3), 147-150, 1999.

Radiographic atlas of skeletal development Radiographic atlas of skeletal development, 1959

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Radiographic atlas of skeletal development Radiographic atlas of skeletal development, 1959. (1999). Pediatrics International: Official Journal of the Japan Pediatric Society 41 …, 1999.

Antiphospholipid antibody syndrome in a pediatric case

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Antiphospholipid antibody syndrome in a pediatric case. (1999). Pediatric Research 45 (5), 767-767, 1999.

Growth and adolescence Growth and adolescence, 1962

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Growth and adolescence Growth and adolescence, 1962. (1999). Pediatrics International: Official Journal of the Japan Pediatric Society 41 …, 1999.

Thromboembolism in β-thalassemia major

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Thromboembolism in β-thalassemia major. (1998). Acta Haematologica 100 (3), 166-166, 1998.

Homozygous protein C deficiency with a double variant His 202 to Tyr and Ala 346 to Thr.

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Homozygous protein C deficiency with a double variant His 202 to Tyr and Ala 346 to Thr. (1998). Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis …, 1998.

Post-splenectomy thrombosis and haemolytic anaemias

Journal Article ,
Post-splenectomy thrombosis and haemolytic anaemias. (1997). British Journal of Haematology 97 (2), 505, 1997.

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Integration in Clinical Clerkships

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Immunodeficiencies in children

What is immunodeficiency? What does it cause? How do you suspect from immunodeficiency? Is it congenital, hereditary or acquired? What types are there?     Case 1 (AT)     A problem-based learning case being discussed in class regards an immunodeficiency disorder involving a 12-year-old boy. Shortly after he began walking, he developed worsening instability and imbalance until he was eventually confined to a wheelchair at 9 years of age. Additionally, he developed oculocutaneous telangiectasias beginning at approximately 3 years of age. During the discussion of this patient’s case, it is added that such patients commonly have chronic sinopulmonary disease and also have a high incidence of malignancy, particularly lymphoreticular malignancies. What is the mechanism of action responsible for this patient’s condition?       (A) Absent respiratory burst     (B) Blocked lysosomal trafficking     (C) Defective DNA repair     (D) Defects in peroxisome function     (E) Impaired toll-like receptor signaling   Case 2: (WAS) A 26-month-old boy, the first child of nonconsanguineous parents, was previously diagnosed as chronic immune thrombocytopenic purpura. Hb 11.7 WBC 4000 Plt 40 000 He was referred to our clinic with recurrent bruising and petechial lesions since 3.5 months of age. He had received prednisolone and intravenous immunoglobulin treatments. He had accompanying  mild transient eczema together with early onset of thrombocytopenia and small platelets.   Case 3: (SCID) A seven months old male infant born of non-consanguineous marriage presented with recurrent oral ulcers, fever along with failure to thrive since 4 months. He had macular rash over face and chest since 1 month. He had been hospitalized for pneumonia 15 days back. He was a full term normal vaginal delivery and birth weight was 3.1 kg. His elder 2 sisters were completely asymptomatic. He had been immunized till date and milestones were normal. On examination, he had pallor with hypo-pigmented macules over neck and perianal region. On examination of oral cavity, tonsils were absent. On systemic examination, he had hepatosplenomegaly. Due to absent tonsils with recurrent infections and failure to thrive, he was suspected to be suffering from a Primary Immunodeficiency. His hemogram showed hemoglobin of 9.2 mg/dl with WBC count of 15,000/cumm [76% polymorphs, 8% Band Forms and 16% lymphocytes] with absolute lymphocyte count of 2400/cumm suggestive of lymphopenia and ESR of 12mm at end of 1 hour. His renal function test, liver function tests, urine and stool examination were normal. His urine culture was suggestive of candida albicans. X-Ray Chest revealed no thymic shadow. His HIV ELISA was negative. His serum immunoglobulins were all elevated [S. IgA = 100 mg/dl, S. IgG = 1426 mg/dl, S. IgM = 160 mg/dl] and CD panel by flow cytometry was suggestive of T- B+ NK- severe combined immunodeficiency most likely X-linked variant [CD3 = 20 cells/cumm, CD4 = 21 cells/cumm, CD8 = 24 cells/cumm, CD19 = 330 cells/cumm, CD20 = 437 cells/cumm, CD56 = 66 cells/cumm, CD16 = 630 cells/cumm]. He was treated with Intravenous Fluconazole and advised regarding Bone Marrow Transplant. In view of oral ulcers, skin rash along with hepatosplenomegaly he was suspected as a case of Graft versus host disease due to engraftment of maternal T cells. However it could not be confirmed by HLA testing as parents were not willing for the same.   Discussion   Severe combined immunodeficiency (SCID) is characterized by abnormal T and B cell function from birth. It is the severest of all congenital immunodeficiencies and unless immunologic reconstitution is achieved through bone marrow transplantation or enzyme replacement, death usually occurs by 2 years of age (1). Several types of SCID have been identified and clinically classified as T-B+ or T-B- SCID depending on affection of B cells. T cells and subsets are low to absent in all types. X linked SCID is the commonest form of SCID and patients present as T-B+ NK- SCID (decreased T cells, normal B cell quantity and low Non-Killer cells) as was seen in our patient. Males are affected. Affected infants present with frequent episodes of diarrhea, pneumonia, sepsis and cutaneous infections within first few months of life. Failure to thrive after infections is common. Viral infections such as Varicella, Measles, Parainfluenzae, CMV, Epstein Barr Virus and fungal infections such as Candida, Pneumocystis Carinii (PCP) are common. Our patient had a candidial urinary tract infection. BCG vaccine can lead to disseminated TB. Infants lack the ability to reject foreign tissue and hence are at risk for graft-versus-host disease from maternal immunocompetent T cells or from T cells in non-irradiated blood transfusion or allogenic bone marrow transplant. Thymus tissue is hypoplastic and hypoplasia of adenoids, tonsils and peripheral lymph nodes is seen as was seen in our patient. Investigations reveal profound lymphopenia with diminished serum immunoglobulins and no antibody formation following investigation. Antibody levels may initially be normal due to passively transferred maternal antibodies. Analysis of lymphocyte subpopulation helps to identify the type of SCID (3). Treatment consists of bone marrow transplant. Gene therapy with enzyme replacement is useful in ADA deficient SCID . 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Immunodeficiencies in children

What is immunodeficiency? What does it cause? How do you suspect from immunodeficiency? Is it congenital, hereditary or acquired? What types are there?     Case 1 (AT)     A problem-based learning case being discussed in class regards an immunodeficiency disorder involving a 12-year-old boy. Shortly after he began walking, he developed worsening instability and imbalance until he was eventually confined to a wheelchair at 9 years of age. Additionally, he developed oculocutaneous telangiectasias beginning at approximately 3 years of age. During the discussion of this patient’s case, it is added that such patients commonly have chronic sinopulmonary disease and also have a high incidence of malignancy, particularly lymphoreticular malignancies. What is the mechanism of action responsible for this patient’s condition?       (A) Absent respiratory burst     (B) Blocked lysosomal trafficking     (C) Defective DNA repair     (D) Defects in peroxisome function     (E) Impaired toll-like receptor signaling   Case 2: (WAS) A 26-month-old boy, the first child of nonconsanguineous parents, was previously diagnosed as chronic immune thrombocytopenic purpura. Hb 11.7 WBC 4000 Plt 40 000 He was referred to our clinic with recurrent bruising and petechial lesions since 3.5 months of age. He had received prednisolone and intravenous immunoglobulin treatments. He had accompanying  mild transient eczema together with early onset of thrombocytopenia and small platelets.   Case 3: (SCID) A seven months old male infant born of non-consanguineous marriage presented with recurrent oral ulcers, fever along with failure to thrive since 4 months. He had macular rash over face and chest since 1 month. He had been hospitalized for pneumonia 15 days back. He was a full term normal vaginal delivery and birth weight was 3.1 kg. His elder 2 sisters were completely asymptomatic. He had been immunized till date and milestones were normal. On examination, he had pallor with hypo-pigmented macules over neck and perianal region. On examination of oral cavity, tonsils were absent. On systemic examination, he had hepatosplenomegaly. Due to absent tonsils with recurrent infections and failure to thrive, he was suspected to be suffering from a Primary Immunodeficiency. His hemogram showed hemoglobin of 9.2 mg/dl with WBC count of 15,000/cumm [76% polymorphs, 8% Band Forms and 16% lymphocytes] with absolute lymphocyte count of 2400/cumm suggestive of lymphopenia and ESR of 12mm at end of 1 hour. His renal function test, liver function tests, urine and stool examination were normal. His urine culture was suggestive of candida albicans. X-Ray Chest revealed no thymic shadow. His HIV ELISA was negative. His serum immunoglobulins were all elevated [S. IgA = 100 mg/dl, S. IgG = 1426 mg/dl, S. IgM = 160 mg/dl] and CD panel by flow cytometry was suggestive of T- B+ NK- severe combined immunodeficiency most likely X-linked variant [CD3 = 20 cells/cumm, CD4 = 21 cells/cumm, CD8 = 24 cells/cumm, CD19 = 330 cells/cumm, CD20 = 437 cells/cumm, CD56 = 66 cells/cumm, CD16 = 630 cells/cumm]. He was treated with Intravenous Fluconazole and advised regarding Bone Marrow Transplant. In view of oral ulcers, skin rash along with hepatosplenomegaly he was suspected as a case of Graft versus host disease due to engraftment of maternal T cells. However it could not be confirmed by HLA testing as parents were not willing for the same.   Discussion   Severe combined immunodeficiency (SCID) is characterized by abnormal T and B cell function from birth. It is the severest of all congenital immunodeficiencies and unless immunologic reconstitution is achieved through bone marrow transplantation or enzyme replacement, death usually occurs by 2 years of age (1). Several types of SCID have been identified and clinically classified as T-B+ or T-B- SCID depending on affection of B cells. T cells and subsets are low to absent in all types. X linked SCID is the commonest form of SCID and patients present as T-B+ NK- SCID (decreased T cells, normal B cell quantity and low Non-Killer cells) as was seen in our patient. Males are affected. Affected infants present with frequent episodes of diarrhea, pneumonia, sepsis and cutaneous infections within first few months of life. Failure to thrive after infections is common. Viral infections such as Varicella, Measles, Parainfluenzae, CMV, Epstein Barr Virus and fungal infections such as Candida, Pneumocystis Carinii (PCP) are common. Our patient had a candidial urinary tract infection. BCG vaccine can lead to disseminated TB. Infants lack the ability to reject foreign tissue and hence are at risk for graft-versus-host disease from maternal immunocompetent T cells or from T cells in non-irradiated blood transfusion or allogenic bone marrow transplant. Thymus tissue is hypoplastic and hypoplasia of adenoids, tonsils and peripheral lymph nodes is seen as was seen in our patient. Investigations reveal profound lymphopenia with diminished serum immunoglobulins and no antibody formation following investigation. Antibody levels may initially be normal due to passively transferred maternal antibodies. Analysis of lymphocyte subpopulation helps to identify the type of SCID (3). Treatment consists of bone marrow transplant. Gene therapy with enzyme replacement is useful in ADA deficient SCID . 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